The prevalence of gastroesophageal reflux disease (GERD) and related disorders has been increasing worldwide, particularly in Western populations where a parallel rise in obesity prevalence has been reported. As weight gain often overlaps with the GERD-related symptoms, several recent studies investigated the significance of this correlation, mainly using meta-analyses. Here, we discuss the large amount of evidence linking obesity and GERD-related symptoms, providing potential mechanisms for their co-occurrence. Particular attention is given also to the association between obesity, Barrett's esophagus and esophageal adenocarcinoma development.
The Role of Obesity in Gastroesophageal Reflux Disease and Barrett's Esophagus / Eusebi LH; Fuccio L; Bazzoli F. - In: DIGESTIVE DISEASES. - ISSN 0257-2753. - STAMPA. - 30:(2012), pp. 154-157. [10.1159/000336668.]
The Role of Obesity in Gastroesophageal Reflux Disease and Barrett's Esophagus.
EUSEBI, LEONARDO HENRY UMBERTO;FUCCIO, LORENZO;BAZZOLI, FRANCO
2012
Abstract
The prevalence of gastroesophageal reflux disease (GERD) and related disorders has been increasing worldwide, particularly in Western populations where a parallel rise in obesity prevalence has been reported. As weight gain often overlaps with the GERD-related symptoms, several recent studies investigated the significance of this correlation, mainly using meta-analyses. Here, we discuss the large amount of evidence linking obesity and GERD-related symptoms, providing potential mechanisms for their co-occurrence. Particular attention is given also to the association between obesity, Barrett's esophagus and esophageal adenocarcinoma development.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
