xThe synthesis of architecturally complex polycyclic fused indolines is achieved in a chemo-, regio-, and stereodefined manner, via an enantioselective gold-catalyzed cascade hydroindolination/iminium trapping synthetic sequence. Highly functionalized tetracyclic fused furoindolines (2) and dihydropyranylindolines (4) are synthesized in moderate to good yields and enantiomeric excesses of up to 87%.

Enantioselective Gold-Catalyzed Synthesis of Polycyclic Indolines

CERA, GIANPIERO;CHIARUCCI, MICHEL;MAZZANTI, ANDREA;MANCINELLI, MICHELE;BANDINI, MARCO
2012

Abstract

xThe synthesis of architecturally complex polycyclic fused indolines is achieved in a chemo-, regio-, and stereodefined manner, via an enantioselective gold-catalyzed cascade hydroindolination/iminium trapping synthetic sequence. Highly functionalized tetracyclic fused furoindolines (2) and dihydropyranylindolines (4) are synthesized in moderate to good yields and enantiomeric excesses of up to 87%.
2012
G. Cera; M. Chiarucci; A. Mazzanti; M. Mancinelli; M. Bandini
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/114406
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