BACKGROUND: The PATER study assessed the frequency of high-risk (HR) and low-risk (LR) human papillomavirus (HPV) in HPV-induced lesions in patients with borderline cytology. METHODS: This retrospective observational cohort study was designed to evaluate ASCUS patients detected through a local cervical cancer screening programme and referred to the Department of Gynaecology and Obstetrics at the S. Orsola-Malpighi University Hospital in Bologna, in the period between January 2000 and December 2007. RESULTS: In 1047 patients aged 38.4 ± 9.6 years (range 23-65 years), 34.8% (n = 364) was positive for HR- or LR-HPV DNA. The mean age of women with HPV infection was significantly lower compared with the negative group (36.8 ± 9.4 versus 39.3 ± 9.6 years; p
Population-based frequency assessment of HPV-induced lesions in patients with borderline Pap tests in the Emilia-Romagna Region: the PATER study / Costa S.; Venturoli S.; Mennini FS.; Marcellusi A.; Pesaresi M.; Leo E.; Falasca A.; Marra E.; Cricca M.; Santini D.; Zerbini M.; Pelusi G.. - In: CURRENT MEDICAL RESEARCH AND OPINION. - ISSN 0300-7995. - ELETTRONICO. - 27:(2011), pp. 569-578. [10.1185/03007995.2010.546730]
Population-based frequency assessment of HPV-induced lesions in patients with borderline Pap tests in the Emilia-Romagna Region: the PATER study.
VENTUROLI, SIMONA;LEO, ELISA;MARRA, ELENA;CRICCA, MONICA;SANTINI, DONATELLA;ZERBINI, MARIALUISA;PELUSI, GIUSEPPE
2011
Abstract
BACKGROUND: The PATER study assessed the frequency of high-risk (HR) and low-risk (LR) human papillomavirus (HPV) in HPV-induced lesions in patients with borderline cytology. METHODS: This retrospective observational cohort study was designed to evaluate ASCUS patients detected through a local cervical cancer screening programme and referred to the Department of Gynaecology and Obstetrics at the S. Orsola-Malpighi University Hospital in Bologna, in the period between January 2000 and December 2007. RESULTS: In 1047 patients aged 38.4 ± 9.6 years (range 23-65 years), 34.8% (n = 364) was positive for HR- or LR-HPV DNA. The mean age of women with HPV infection was significantly lower compared with the negative group (36.8 ± 9.4 versus 39.3 ± 9.6 years; pI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
