The possibility to visualize pathological tissues for example tumor neo-angiogenesis pattern-, using new X-ray imaging technique (such as Multi-Energy subtraction X-ray Imaging) is strictly related to an accurate knowledge of the X-ray absorption coefficients. Unfortunately, |i(E) values are partially derived from Monte Carlo simulation and known only for a little number of pathologies. A study of the attenuation properties of tissues was started at the University of Bologna in order to experimentally investigate their proprieties. Tissues X-ray attenuation curves are measured in a facility based on a Bragg monochromator with a lithium-fluoride crystal, to have beams with X-ray energies from 10 keV to 60 keV and energy resolution less than 2.0 keV. Different methods of analysis are implemented, starting from algorithms that can extract chemical-physical information from X-ray absorption measurements, such as effective atomic number and electron density. © 2008 IEEE.

Characterization of Biological Tissues using X-ray Attenuation Data

BALDAZZI, GIUSEPPE;ROSSI, PIER LUCA;MASETTI, SIMONE;LANCONELLI, NICO;BIANCHINI, DAVID;NICOLETTI, GIORDANO;LOLLINI, PIER LUIGI;Turco, A.;Roma, L.
2008

Abstract

The possibility to visualize pathological tissues for example tumor neo-angiogenesis pattern-, using new X-ray imaging technique (such as Multi-Energy subtraction X-ray Imaging) is strictly related to an accurate knowledge of the X-ray absorption coefficients. Unfortunately, |i(E) values are partially derived from Monte Carlo simulation and known only for a little number of pathologies. A study of the attenuation properties of tissues was started at the University of Bologna in order to experimentally investigate their proprieties. Tissues X-ray attenuation curves are measured in a facility based on a Bragg monochromator with a lithium-fluoride crystal, to have beams with X-ray energies from 10 keV to 60 keV and energy resolution less than 2.0 keV. Different methods of analysis are implemented, starting from algorithms that can extract chemical-physical information from X-ray absorption measurements, such as effective atomic number and electron density. © 2008 IEEE.
2008 IEEE Nuclear Science Symposium Conference Record
4798
4802
G. Baldazzi; P. L. Rossi; S. Masetti; A. Turco; M. Fiaschetti; N. Lanconelli; D. Bianchini; L. Roma; G. Nicoletti; P. L. Lollini
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/111443
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