Fusarium is an opportunistic fungal pathogen which is emerging as a significant cause of morbidity and mortality in the immunocompromised host [Fleming RV, Walsh TJ, Anaissie EJ. Emerging and less common fungal pathogens. Infect Dis Clin North Am 2002;16:915-34]. This disease can be localized, focally invasive or disseminated, when two or more noncontiguous sites are involved. Therapeutic options are scarce and mortality reaches 80-90% in patients subjected to allogeneic hematopoietic stem cell transplant (allo-SCT) [Nucci M, Marr KA, Queiroz-Telles F, Martins CA, Trabasso P, Costa S, et al. Fusarium infection in hematopoietic stem cell transplant recipient. Clin Infect Dis 2004;1237-42]. We report a case of disseminated Fusariosis in a severe immunocompromised patient after allo-SCT that responded to treatment with the early combination of intravenous voriconazole and liposomal amphotericin B.

M. Stanzani, N. Vianelli, G. Bandini, S. Paolini, M. Arpinati, F. Bonifazi, et al. (2006). Successful treatment of disseminated Fusariosis after allogeneic hematopoietic stem cell transplantation with the combination of voriconazole and liposomal amphotericin B. JOURNAL OF INFECTION, 53(6), e243-e246 [10.1016/j.jinf.2006.02.011].

Successful treatment of disseminated Fusariosis after allogeneic hematopoietic stem cell transplantation with the combination of voriconazole and liposomal amphotericin B

STANZANI, MARTA;VIANELLI, NICOLA;BANDINI, GIUSEPPE;PAOLINI, STEFANIA;ARPINATI, MARIO;BONIFAZI, FRANCESCA;AGOSTINELLI, CLAUDIO;BACCARANI, MICHELE;RICCI, PAOLO
2006

Abstract

Fusarium is an opportunistic fungal pathogen which is emerging as a significant cause of morbidity and mortality in the immunocompromised host [Fleming RV, Walsh TJ, Anaissie EJ. Emerging and less common fungal pathogens. Infect Dis Clin North Am 2002;16:915-34]. This disease can be localized, focally invasive or disseminated, when two or more noncontiguous sites are involved. Therapeutic options are scarce and mortality reaches 80-90% in patients subjected to allogeneic hematopoietic stem cell transplant (allo-SCT) [Nucci M, Marr KA, Queiroz-Telles F, Martins CA, Trabasso P, Costa S, et al. Fusarium infection in hematopoietic stem cell transplant recipient. Clin Infect Dis 2004;1237-42]. We report a case of disseminated Fusariosis in a severe immunocompromised patient after allo-SCT that responded to treatment with the early combination of intravenous voriconazole and liposomal amphotericin B.
2006
M. Stanzani, N. Vianelli, G. Bandini, S. Paolini, M. Arpinati, F. Bonifazi, et al. (2006). Successful treatment of disseminated Fusariosis after allogeneic hematopoietic stem cell transplantation with the combination of voriconazole and liposomal amphotericin B. JOURNAL OF INFECTION, 53(6), e243-e246 [10.1016/j.jinf.2006.02.011].
M. Stanzani; N. Vianelli; G. Bandini; S. Paolini; M. Arpinati; F. Bonifazi; B. Giannini; C. Agostinelli; M. Baccarani; P. Ricci.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/108299
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