Stereoselective synthesis of non-proteinogenic di- and tri-peptides containing L-valine unit and a cyclic unnatural alpha-amino acid has been accomplished starting from the L-valine derived chiral synthon. The conformational preference of these unnatural peptides was investigated by 1H-NMR and IR spectroscopies and by molecular modelling calculations. X-ray analysis is also reported.

Synthesis and conformational preferences of cyclic unnatural di- and tri-peptides containing L-Valine unit. Part 2

BALDUCCI, DANIELE;EMER, ENRICO;PICCINELLI, FABIO;PORZI, GIANNI;RECANATINI, MAURIZIO;SANDRI, SERGIO
2005

Abstract

Stereoselective synthesis of non-proteinogenic di- and tri-peptides containing L-valine unit and a cyclic unnatural alpha-amino acid has been accomplished starting from the L-valine derived chiral synthon. The conformational preference of these unnatural peptides was investigated by 1H-NMR and IR spectroscopies and by molecular modelling calculations. X-ray analysis is also reported.
D. Balducci; E. Emer; F. Piccinelli; G. Porzi; M. Recanatini; S. Sandri
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/10805
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