Stereoselective synthesis of non-proteinogenic di- and tri-peptides containing L-valine unit and a cyclic unnatural alpha-amino acid has been accomplished starting from the L-valine derived chiral synthon. The conformational preference of these unnatural peptides was investigated by 1H-NMR and IR spectroscopies and by molecular modelling calculations. X-ray analysis is also reported.
Synthesis and conformational preferences of cyclic unnatural di- and tri-peptides containing L-Valine unit. Part 2 / D. Balducci; E. Emer; F. Piccinelli; G. Porzi; M. Recanatini; S. Sandri. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - STAMPA. - 16:(2005), pp. 3785-3794. [10.1016/j.tetasy.2005.10.030]
Synthesis and conformational preferences of cyclic unnatural di- and tri-peptides containing L-Valine unit. Part 2
BALDUCCI, DANIELE;EMER, ENRICO;PICCINELLI, FABIO;PORZI, GIANNI;RECANATINI, MAURIZIO;SANDRI, SERGIO
2005
Abstract
Stereoselective synthesis of non-proteinogenic di- and tri-peptides containing L-valine unit and a cyclic unnatural alpha-amino acid has been accomplished starting from the L-valine derived chiral synthon. The conformational preference of these unnatural peptides was investigated by 1H-NMR and IR spectroscopies and by molecular modelling calculations. X-ray analysis is also reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
