A polymeric membrane-based ion-selective electrode (ISE) for the determination of l-ascorbic acid (l- AA) was developed. The sensor was fabricated by modifying glassy carbon electrodes with molecularly imprinted polypyrrole (PPy) synthesized by electropolymerization of the monomer in the presence of ascorbate. A comparison between the non-imprinted modified electrode (PPy-NIP) and the molecularly imprinted polymer (PPy-MIP) is reported. The molecularly imprinted polymer improves the performances of the sensor, especially if the PPy film has been submitted to an oxidation treatment. The PPy-MIPox electrode shows near-Nernstian response (approx. −57 mV/decade) to the ascorbate over the concentration range between 5 × 10−6M and 2 × 10−3M and it can be used for more than 3 weeks without any considerable change in the measured response. The potentiometric sensor has been successfully applied to the determination of ascorbate in food and pharmaceutical samples (recoveries of about 100%).

A novel potentiometric sensor for l-ascorbic acid based on molecularly imprinted polypyrrole

TONELLI, DOMENICA;BALLARIN, BARBARA;GUADAGNINI, LORELLA;MIGNANI, ADRIANA;SCAVETTA, ERIKA
2011

Abstract

A polymeric membrane-based ion-selective electrode (ISE) for the determination of l-ascorbic acid (l- AA) was developed. The sensor was fabricated by modifying glassy carbon electrodes with molecularly imprinted polypyrrole (PPy) synthesized by electropolymerization of the monomer in the presence of ascorbate. A comparison between the non-imprinted modified electrode (PPy-NIP) and the molecularly imprinted polymer (PPy-MIP) is reported. The molecularly imprinted polymer improves the performances of the sensor, especially if the PPy film has been submitted to an oxidation treatment. The PPy-MIPox electrode shows near-Nernstian response (approx. −57 mV/decade) to the ascorbate over the concentration range between 5 × 10−6M and 2 × 10−3M and it can be used for more than 3 weeks without any considerable change in the measured response. The potentiometric sensor has been successfully applied to the determination of ascorbate in food and pharmaceutical samples (recoveries of about 100%).
D.Tonelli; B. Ballarin; L. Guadagnini; A. Mignani; E.Scavetta
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/107885
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