Safety and efficacy of a feed additive consisting of l‐valine produced with Corynebacterium glutamicum CCTCC M 20232578 for all animal species (Kempex Holland B.V.)

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-valine produced with a non-genetically modified strain of Corynebacterium glutamicum (CCTCC M 20232578) as a nutritional feed additive, to be used in feed or water for drinking for all animal species and categories. The production strain meets the qualifications for the qualified presumption of safety (QPS) approach to safety assessment and is considered safe. The use of l-valine produced with C. glutamicum CCTCC M 20232578 in feed was considered safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the species. The FEEDAP Panel had concerns about the use of l-valine in water for drinking. The use of l-valine produced by fermentation with C. glutamicum CCTCC M 20232578 in animal nutrition was considered safe for the consumers of products from animals receiving the additive and to the environment. The FEEDAP Panel could not conclude on the potential of the additive to be irritant to skin and/or eyes and to be a potential skin sensitiser. The additive was regarded as an effective source of the amino acid l-valine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.