Stereoselective synthesis of some pseudopeptides incorporating 2,6-diamino-4-methylen-1,7-heptanedioic acid residue has been accomplished starting from the L-valine derived chiral synthon. The absolute configuration of new stereocenters was assigned on the basis of 1H-NMR spectra. The geometry of these unnatural tripeptides was deduced on the basis of 1H-NMR parameters and IR spectra. X-ray analysis and conformational studies are also reported.
D. Balducci, S. Crupi, R. Galeazzi, F. Piccinelli, G. Porzi, S. Sandri (2005). Stereoselective approach to uncommon tripeptides incorporating 2,6-diaminopimelic acid framework. X-ray analysis and conformational studies. Part 4. TETRAHEDRON-ASYMMETRY, 16, 1103-1112 [10.1016/j.tetasy.2005.01.047].
Stereoselective approach to uncommon tripeptides incorporating 2,6-diaminopimelic acid framework. X-ray analysis and conformational studies. Part 4
BALDUCCI, DANIELE;PICCINELLI, FABIO;PORZI, GIANNI;SANDRI, SERGIO
2005
Abstract
Stereoselective synthesis of some pseudopeptides incorporating 2,6-diamino-4-methylen-1,7-heptanedioic acid residue has been accomplished starting from the L-valine derived chiral synthon. The absolute configuration of new stereocenters was assigned on the basis of 1H-NMR spectra. The geometry of these unnatural tripeptides was deduced on the basis of 1H-NMR parameters and IR spectra. X-ray analysis and conformational studies are also reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
