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EnglishOBJECTIVES: To evaluate the accuracy of three-dimensional (3D) ultrasound in fetal gender assignment in the first trimester. METHODS: A series of pregnant women attending at 11 to 13 + 6 weeks for the nuchal translucency (NT) scan were enrolled into the study. An ultrasound volume of each fetus was obtained and stored for offline analysis. On the reconstructed mid-sagittal plane, the angle between the genital tubercle and an imaginary line passing tangentially through the fetal back (genital angle) was estimated and a receiver-operating characteristics (ROC) curve was constructed to determine the best cut-off for genital angle in fetal male gender determination. Fetal gender was subsequently ascertained in all cases. To calculate the interobserver variability, a second operator repeated the measurements. RESULTS: There were 85 cases included in the study. The genital angle in males was significantly higher than that in females (51.2 +/- 11.3 degrees (n = 36) vs. 18.9 +/- 4.1 (n = 49), P < 0.001). The ROC curve revealed the estimated genital angle to have a high degree of accuracy in fetal gender determination (area under the curve +/- SE = 1.000 +/- 0.001). The best cut-off for male gender determination was found to be between 27 degrees and 29 degrees (sensitivity, 100%; specificity, 98.0%). There was a high degree of correlation between the two operators (r(2) = 0.998; coefficient of variation = 5.4%). CONCLUSIONS: 3D ultrasound is a highly accurate and reproducible tool for fetal gender assignment prior to 14 weeks of gestation.
| Titolo: | Accuracy of fetal gender determination in the first trimester using three-dimensional ultrasound. | |
| Autore/i: | Youssef A.; Arcangeli T.; Radico D.; Contro E.; Guasina F.; Bellussi F.; Maroni E.; Morselli Labate A. M.; FARINA, ANTONIO; PILU, GIANLUIGI; Pelusi G.; GHI, TULLIO | |
| Autore/i Unibo: | ||
| Anno: | 2011 | |
| Rivista: | ||
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/uog.8812 | |
| Abstract: | OBJECTIVES: To evaluate the accuracy of three-dimensional (3D) ultrasound in fetal gender assignment in the first trimester. METHODS: A series of pregnant women attending at 11 to 13 + 6 weeks for the nuchal translucency (NT) scan were enrolled into the study. An ultrasound volume of each fetus was obtained and stored for offline analysis. On the reconstructed mid-sagittal plane, the angle between the genital tubercle and an imaginary line passing tangentially through the fetal back (genital angle) was estimated and a receiver-operating characteristics (ROC) curve was constructed to determine the best cut-off for genital angle in fetal male gender determination. Fetal gender was subsequently ascertained in all cases. To calculate the interobserver variability, a second operator repeated the measurements. RESULTS: There were 85 cases included in the study. The genital angle in males was significantly higher than that in females (51.2 +/- 11.3 degrees (n = 36) vs. 18.9 +/- 4.1 (n = 49), P < 0.001). The ROC curve revealed the estimated genital angle to have a high degree of accuracy in fetal gender determination (area under the curve +/- SE = 1.000 +/- 0.001). The best cut-off for male gender determination was found to be between 27 degrees and 29 degrees (sensitivity, 100%; specificity, 98.0%). There was a high degree of correlation between the two operators (r(2) = 0.998; coefficient of variation = 5.4%). CONCLUSIONS: 3D ultrasound is a highly accurate and reproducible tool for fetal gender assignment prior to 14 weeks of gestation. | |
| Data prodotto definitivo in UGOV: | 2013-06-11 13:31:51 | |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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