The influence of a very-low-calorie diet (VLCD) on lipid pattern is controversial. To evaluate the long-term effect of semistarvation on lipid patterns, a group of severely obese patients [aged 37 ± 12 y, body mass index (BMI) 40.0 ± 0.9] underwent a VLCD for 8 wk. Total cholesterol (TC), LDL cholesterol (LDL-C), and HDL cholesterol (HDL-C), triglycerides (TGs), apolipoproteins A1 (apo A1) and B (apo B) were analyzed every week. TC (6.07 ± 0.23 vs 5.53 ± 0.25 mmol/ L, P < 0.0008), HDL-C (mmol//L 1.26 ± 0.06 vs 1.04 ± 0.05 mmol/L, P < 0.0001 ), TGs (1.46 ± 0.19 vs 1.06 ± 0.10 mmol/ L, P < 0.0008), and apo A1 (1.57 ± 0.06 vs 1.32 ± 0.06 g/L, P < 0.0002) decreased, whereas LDL-C and apo B showed a biphasic behavior: they significantly fell during the first 3 wk, but during the last weeks returned to their initial values.
Parenti, M., Babini, A.C., Cecchetto, M.E., Di Bartolo, P., Luchi, A., Saretta, B., et al. (1992). Lipid, lipoprotein, and apolipoprotein assessment during an 8-wk very-low-calorie diet. THE AMERICAN JOURNAL OF CLINICAL NUTRITION, 56(1), 1-4.
Lipid, lipoprotein, and apolipoprotein assessment during an 8-wk very-low-calorie diet
Di Bartolo P.;Motta R.;Melchionda N.;Barbara L.
1992
Abstract
The influence of a very-low-calorie diet (VLCD) on lipid pattern is controversial. To evaluate the long-term effect of semistarvation on lipid patterns, a group of severely obese patients [aged 37 ± 12 y, body mass index (BMI) 40.0 ± 0.9] underwent a VLCD for 8 wk. Total cholesterol (TC), LDL cholesterol (LDL-C), and HDL cholesterol (HDL-C), triglycerides (TGs), apolipoproteins A1 (apo A1) and B (apo B) were analyzed every week. TC (6.07 ± 0.23 vs 5.53 ± 0.25 mmol/ L, P < 0.0008), HDL-C (mmol//L 1.26 ± 0.06 vs 1.04 ± 0.05 mmol/L, P < 0.0001 ), TGs (1.46 ± 0.19 vs 1.06 ± 0.10 mmol/ L, P < 0.0008), and apo A1 (1.57 ± 0.06 vs 1.32 ± 0.06 g/L, P < 0.0002) decreased, whereas LDL-C and apo B showed a biphasic behavior: they significantly fell during the first 3 wk, but during the last weeks returned to their initial values.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
