Heavy use of antioxidants in equine in vitro fertilisation (IVF) media may suppress the reactive oxygen species (ROS) signals stallion sperm need for capacitation, which depends on high mitochondrial activity and a well-maintained endogenous redox homeostasis. A species-specific approach balancing oxidative protection with controlled ROS signalling could improve fertilisation efficiency and reduce prolonged incubation times.
Medica, A.J., Gibb, Z., Ortiz-Rodriguez, J.M., Swegen, A. (2026). Are antioxidants hindering stallion sperm capacitation? A perspective on hidden barriers to equine IVF success. REPRODUCTION FERTILITY AND DEVELOPMENT, 38(5), 1-2 [10.1071/rd26009].
Are antioxidants hindering stallion sperm capacitation? A perspective on hidden barriers to equine IVF success
Ortiz-Rodriguez, Jose Manuel;
2026
Abstract
Heavy use of antioxidants in equine in vitro fertilisation (IVF) media may suppress the reactive oxygen species (ROS) signals stallion sperm need for capacitation, which depends on high mitochondrial activity and a well-maintained endogenous redox homeostasis. A species-specific approach balancing oxidative protection with controlled ROS signalling could improve fertilisation efficiency and reduce prolonged incubation times.| File | Dimensione | Formato | |
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