Clinical Factors Influencing Improvement in Disorganization in Clinical High-Risk for Psychosis: Preliminary Findings From a 2-Year Follow-Up

Disorganization is under-treated in early psychosis. We aimed at exploring clinical factors potentially improving disorganization in individuals at Clinical High Risk for Psychosis (CHR-P) across 2 years of follow-up. About 180 participants completed the GAF and the PANSS. Longitudinally, 111 (61.7%) individuals had a decrease in disorganization. Significant associations of this improvement were with shorter duration of untreated illness, higher improvement in negative symptoms, and antipsychotic prescription.