Bloodstream infections are a significant cause of morbidity and mortality among hemodialysis patients. These infections primarily involve Gram-positive bacteria and, less frequently, Gram-negative bacilli. Raoultella ornithinolytica is a Gram-negative bacillus which is known to be a rare opportunistic pathogen. It is found only occasionally in human infections; however, it has been noted as an emerging pathogen. Sepsis caused by this microorganism is very rare. A few cases have been reported among immunocompromised patients or those undergoing invasive procedures. Cases involving urinary catheters or port catheters have also been reported, as well as a single case of a patient on peritoneal dialysis. Here, we present a novel case of Raoultella ornithinolytica bloodstream infection in a patient with chronic renal failure undergoing hemodialysis who was successfully treated. We discuss the microbiology and clinical features of such infections, and consider aspects of treatment.
Righini, M., Titone, M., Martelli, D., Isola, E., Tampieri, E., Graziani, R., et al. (2025). Bloodstream Infection Caused by Raoultella ornithinolytica in a Chronic Hemodialysis Patient. KIDNEY AND DIALYSIS, 5(3), 1-7 [10.3390/kidneydial5030033].
Bloodstream Infection Caused by Raoultella ornithinolytica in a Chronic Hemodialysis Patient
Righini Matteo
;Martina Titone;Davide Martelli;Chiara Valentini;Matteo De Liberali;Antonella Troiano;Mattia Monti;Vera Minerva;Lilio Hu;Brunilda Sejdiu;Olga Baraldi;Andrea Buscaroli
2025
Abstract
Bloodstream infections are a significant cause of morbidity and mortality among hemodialysis patients. These infections primarily involve Gram-positive bacteria and, less frequently, Gram-negative bacilli. Raoultella ornithinolytica is a Gram-negative bacillus which is known to be a rare opportunistic pathogen. It is found only occasionally in human infections; however, it has been noted as an emerging pathogen. Sepsis caused by this microorganism is very rare. A few cases have been reported among immunocompromised patients or those undergoing invasive procedures. Cases involving urinary catheters or port catheters have also been reported, as well as a single case of a patient on peritoneal dialysis. Here, we present a novel case of Raoultella ornithinolytica bloodstream infection in a patient with chronic renal failure undergoing hemodialysis who was successfully treated. We discuss the microbiology and clinical features of such infections, and consider aspects of treatment.| File | Dimensione | Formato | |
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