What is the clinical question being addressed? What are the characteristics and medical lifetrajectories of HoFH patients treated in contemporary health care? What is the main finding? This analysis of HoFH patients highlights the young age at death, mostly from cardiovascular causes, and the low attainment of LDL-C goals despite treatment advances, underscoring the need for earlier diagnosis and better treatment
Mulder, J.W.C.M., Reijman, M.D., Kusters, D.M., Boersma, E., Alnouri, F., Blom, D.J., et al. (2025). Homozygous Familial Hypercholesterolemia Is a Life-Limiting Condition: Medical Life-Trajectories in the Post-2010 Era. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 85(19), 1898-1903 [10.1016/j.jacc.2025.04.005].
Homozygous Familial Hypercholesterolemia Is a Life-Limiting Condition: Medical Life-Trajectories in the Post-2010 Era
Arca M.Membro del Collaboration Group
;Cesaro A.Membro del Collaboration Group
;D'Addato S.Membro del Collaboration Group
;Del Ben M.Membro del Collaboration Group
;Lago J.Membro del Collaboration Group
;
2025
Abstract
What is the clinical question being addressed? What are the characteristics and medical lifetrajectories of HoFH patients treated in contemporary health care? What is the main finding? This analysis of HoFH patients highlights the young age at death, mostly from cardiovascular causes, and the low attainment of LDL-C goals despite treatment advances, underscoring the need for earlier diagnosis and better treatmentI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
