Objectives: To develop a simplified MRI-based shorthand assessment method, referred to as the Sagittal Tibial Epi-Physis (STEP) Shorthand, for skeletal age assessment in skeletally immature patients with anterior cruciate ligament (ACL) injuries. This study aimed to elaborate a single-plane MRI-based skeletal age estimation tool and to explore its feasibility and inter-rater reliability in comparison with existing MRI-based shorthands. Methods: This prospective study included 130 knee MRIs (79% males) from 97 skeletally immature patients (overall average age of 14.0 ± 2.1 years) with ACL injuries treated between February 2022 and January 2025. A new shorthand assessment method was developed based on sagittal T1-weighted MRI evaluation of the proximal tibial epiphysis. A validation cohort of 74 MRIs was independently evaluated by four raters with different levels of expertise using the STEP, Meza, and Politzer shorthand atlases. Inter-rater reliability (ICC), intra-rater agreement (Cohen’s kappa), and association with chronological age (Spearman rho) were calculated. Results: The STEP Shorthand tool demonstrated a strong association with chronological age (rho = 0.890, p < 0.001) with consistent associations across sex subgroups. Inter-rater reliability was high and comparable to established MRI-based shorthands. The use of a focused sagittal T1-weighted evaluation allowed for a simplified and reproducible assessment across raters with varying experience levels. Conclusions: The STEP Shorthand represents a pragmatic and reliable tool for MRI-based skeletal age assessment in pediatric and adolescent patients with ACL injuries. The STEP Shorthand can support timely decision-making in surgical planning and enhance standardization across different levels of clinical expertise.
Grassi, A., Rossi, C., Ambrosini, L., Nakanishi, Y., Ozbek, E.A., Assaf, A., et al. (2026). Simplified Knee MRI ‘Sagittal Tibial Epi-Physis (STEP)’ Shorthand for Skeletal Age Assessment in Pediatric Patients with ACL Injury. DIAGNOSTICS, 16(3), 1-12 [10.3390/diagnostics16030442].
Simplified Knee MRI ‘Sagittal Tibial Epi-Physis (STEP)’ Shorthand for Skeletal Age Assessment in Pediatric Patients with ACL Injury
Grassi A.
;Rossi C.
;Ambrosini L.;Zaffagnini S.
2026
Abstract
Objectives: To develop a simplified MRI-based shorthand assessment method, referred to as the Sagittal Tibial Epi-Physis (STEP) Shorthand, for skeletal age assessment in skeletally immature patients with anterior cruciate ligament (ACL) injuries. This study aimed to elaborate a single-plane MRI-based skeletal age estimation tool and to explore its feasibility and inter-rater reliability in comparison with existing MRI-based shorthands. Methods: This prospective study included 130 knee MRIs (79% males) from 97 skeletally immature patients (overall average age of 14.0 ± 2.1 years) with ACL injuries treated between February 2022 and January 2025. A new shorthand assessment method was developed based on sagittal T1-weighted MRI evaluation of the proximal tibial epiphysis. A validation cohort of 74 MRIs was independently evaluated by four raters with different levels of expertise using the STEP, Meza, and Politzer shorthand atlases. Inter-rater reliability (ICC), intra-rater agreement (Cohen’s kappa), and association with chronological age (Spearman rho) were calculated. Results: The STEP Shorthand tool demonstrated a strong association with chronological age (rho = 0.890, p < 0.001) with consistent associations across sex subgroups. Inter-rater reliability was high and comparable to established MRI-based shorthands. The use of a focused sagittal T1-weighted evaluation allowed for a simplified and reproducible assessment across raters with varying experience levels. Conclusions: The STEP Shorthand represents a pragmatic and reliable tool for MRI-based skeletal age assessment in pediatric and adolescent patients with ACL injuries. The STEP Shorthand can support timely decision-making in surgical planning and enhance standardization across different levels of clinical expertise.| File | Dimensione | Formato | |
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