Occupational-Related Exposure to Diesel Exhaust and Kidney Cancer: Systematic Review and Meta-Analysis of Cohort Studies

Background: The association between diesel exhaust and cancer other than the lung is not well established. We aimed to conduct a systematic review and meta-analysis on the association between diesel exhaust exposure and kidney cancer in workers. Methods: Two trained researchers conducted a systematic review to identify cohort studies examining the relationship between occupational exposure to diesel exhaust and the risk of cancer other than lung cancer. Of the 43 retained studies, 15 reported information on kidney cancer. We performed random-effects meta-analyses for ever-exposure to diesel exhaust. Summary relative risks (RR) and 95% confidence intervals (CI) were calculated for the f kidney cancer was 1.08 nce (95% CI=1.01-1.16; e summary RR of Euro-.10 (95% CI=0.94-1.29, Workers exposed to diesel is not entirely consistent,.