The addition of organolithium reagents to the trianglimine derived from (R,R)-1,2-diaminocyclohexane and terephthalaldehyde gave the corresponding trianglamine with complete stereocontrol and the R configuration of all six newly formed stereocenters. The structure of the hexaphenyl-substituted macrocyle was determined by X-ray crystallographic study. The new trianglamines were tested as ligands in enantioselective catalytic reactions.
Stereoselective synthesis of ring C-hexasubstituted trianglamines / D. Savoia; A. Gualandi; H. Stoeckli-Evans. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - STAMPA. - 8:(2010), pp. 3992-3996. [10.1039/c004873a]
Stereoselective synthesis of ring C-hexasubstituted trianglamines
SAVOIA, DIEGO;GUALANDI, ANDREA;
2010
Abstract
The addition of organolithium reagents to the trianglimine derived from (R,R)-1,2-diaminocyclohexane and terephthalaldehyde gave the corresponding trianglamine with complete stereocontrol and the R configuration of all six newly formed stereocenters. The structure of the hexaphenyl-substituted macrocyle was determined by X-ray crystallographic study. The new trianglamines were tested as ligands in enantioselective catalytic reactions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
