The addition of organolithium reagents to the trianglimine derived from (R,R)-1,2-diaminocyclohexane and terephthalaldehyde gave the corresponding trianglamine with complete stereocontrol and the R configuration of all six newly formed stereocenters. The structure of the hexaphenyl-substituted macrocyle was determined by X-ray crystallographic study. The new trianglamines were tested as ligands in enantioselective catalytic reactions.
D. Savoia, A. Gualandi, H. Stoeckli-Evans (2010). Stereoselective synthesis of ring C-hexasubstituted trianglamines. ORGANIC & BIOMOLECULAR CHEMISTRY, 8, 3992-3996 [10.1039/c004873a].
Stereoselective synthesis of ring C-hexasubstituted trianglamines
SAVOIA, DIEGO;GUALANDI, ANDREA;
2010
Abstract
The addition of organolithium reagents to the trianglimine derived from (R,R)-1,2-diaminocyclohexane and terephthalaldehyde gave the corresponding trianglamine with complete stereocontrol and the R configuration of all six newly formed stereocenters. The structure of the hexaphenyl-substituted macrocyle was determined by X-ray crystallographic study. The new trianglamines were tested as ligands in enantioselective catalytic reactions.File in questo prodotto:
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