Speech impairments in Parkinson's disease (PD) provide significant early indicators for diagnosis. While models for speech-based PD detection have shown strong performance, their interpretability remains underexplored. This study systematically evaluates several explainability methods to identify PD-specific speech features, aiming to support the development of accurate, interpretable models for clinical decision-making in PD diagnosis and monitoring. Our methodology involves (i) obtaining attributions and saliency maps using mainstream interpretability techniques, (ii) quantitatively evaluating the faithfulness of these maps and their combinations obtained via union and intersection through a range of established metrics, and (iii) assessing the information conveyed by the saliency maps for PD detection from an auxiliary classifier. Our results reveal that, while explanations are aligned with the classifier, they often fail to provide valuable information for domain experts.

Mancini, E., Paissan, F., Torroni, P., Ravanelli, M., Subakan, C. (2025). Investigating the Effectiveness of Explainability Methods in Parkinson’s Detection from Speech. Institute of Electrical and Electronics Engineers Inc. [10.1109/icasspw65056.2025.11011035].

Investigating the Effectiveness of Explainability Methods in Parkinson’s Detection from Speech

Mancini, Eleonora
Co-primo
Investigation
;
Torroni, Paolo
Supervision
;
2025

Abstract

Speech impairments in Parkinson's disease (PD) provide significant early indicators for diagnosis. While models for speech-based PD detection have shown strong performance, their interpretability remains underexplored. This study systematically evaluates several explainability methods to identify PD-specific speech features, aiming to support the development of accurate, interpretable models for clinical decision-making in PD diagnosis and monitoring. Our methodology involves (i) obtaining attributions and saliency maps using mainstream interpretability techniques, (ii) quantitatively evaluating the faithfulness of these maps and their combinations obtained via union and intersection through a range of established metrics, and (iii) assessing the information conveyed by the saliency maps for PD detection from an auxiliary classifier. Our results reveal that, while explanations are aligned with the classifier, they often fail to provide valuable information for domain experts.
2025
2025 IEEE International Conference on Acoustics, Speech, and Signal Processing Workshops (ICASSPW)
1
5
Mancini, E., Paissan, F., Torroni, P., Ravanelli, M., Subakan, C. (2025). Investigating the Effectiveness of Explainability Methods in Parkinson’s Detection from Speech. Institute of Electrical and Electronics Engineers Inc. [10.1109/icasspw65056.2025.11011035].
Mancini, Eleonora; Paissan, Francesco; Torroni, Paolo; Ravanelli, Mirco; Subakan, Cem
File in questo prodotto:
File Dimensione Formato  
_SPADE____Parkinson_s_Interpretability.pdf

embargo fino al 26/11/2026

Tipo: Postprint / Author's Accepted Manuscript (AAM) - versione accettata per la pubblicazione dopo la peer-review
Licenza: Licenza per accesso libero gratuito
Dimensione 913.55 kB
Formato Adobe PDF
913.55 kB Adobe PDF   Visualizza/Apri   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/1023488
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? ND
social impact