: Chronic kidney disease (CKD) is a widespread condition with significant cardiovascular risks and a progression to end-stage kidney failure. In recent years, increasing attention has been paid to the role of dietary interventions as a factor capable of influencing disease trajectory. This review summarizes the current observational and interventional evidence on various dietary approaches in patients with CKD and kidney transplants (KTs), including Mediterranean, plant-based, and low-protein diets. A balanced Mediterranean diet, rich in fruits, vegetables, whole grains, fish, and unsaturated fats, shows promises in improving the prognosis for CKD patients. Plant-based diets, which emphasize legumes, vegetables, and grains while minimizing animal protein, improve blood pressure and the glycemic and lipid control. Low-protein diets (LPDs), typically providing less than 0.6 g/kg/day of protein, may reduce the CKD progression and nitrogen burden, further delaying the initiation of dialysis. In conclusion, diets represent a valuable and underutilized therapeutic strategy in the management of CKD and KTs, influencing disease progression and patient outcomes.

Hu, L., Borelli, G., Gessaroli, E., Ruotolo, C., Bin, S., Papalia, G., et al. (2025). Individualized Diets in Patients with Kidney Disease and Kidney Transplants: A Narrative Review. LIFE, 15(6), 1-29 [10.3390/life15060896].

Individualized Diets in Patients with Kidney Disease and Kidney Transplants: A Narrative Review

Hu, Lilio
Primo
;
Borelli, Greta;Gessaroli, Elisa;Bin, Sofia;Papalia, Giuliana;Baraldi, Olga;Capelli, Irene
Penultimo
;
Provenzano, Michele
Ultimo
2025

Abstract

: Chronic kidney disease (CKD) is a widespread condition with significant cardiovascular risks and a progression to end-stage kidney failure. In recent years, increasing attention has been paid to the role of dietary interventions as a factor capable of influencing disease trajectory. This review summarizes the current observational and interventional evidence on various dietary approaches in patients with CKD and kidney transplants (KTs), including Mediterranean, plant-based, and low-protein diets. A balanced Mediterranean diet, rich in fruits, vegetables, whole grains, fish, and unsaturated fats, shows promises in improving the prognosis for CKD patients. Plant-based diets, which emphasize legumes, vegetables, and grains while minimizing animal protein, improve blood pressure and the glycemic and lipid control. Low-protein diets (LPDs), typically providing less than 0.6 g/kg/day of protein, may reduce the CKD progression and nitrogen burden, further delaying the initiation of dialysis. In conclusion, diets represent a valuable and underutilized therapeutic strategy in the management of CKD and KTs, influencing disease progression and patient outcomes.
2025
Hu, L., Borelli, G., Gessaroli, E., Ruotolo, C., Bin, S., Papalia, G., et al. (2025). Individualized Diets in Patients with Kidney Disease and Kidney Transplants: A Narrative Review. LIFE, 15(6), 1-29 [10.3390/life15060896].
Hu, Lilio; Borelli, Greta; Gessaroli, Elisa; Ruotolo, Chiara; Bin, Sofia; Papalia, Giuliana; Patella, Gemma; Liberti, Maria Elena; Baraldi, Olga; Zaza...espandi
File in questo prodotto:
File Dimensione Formato  
life-15-00896-v2.pdf

accesso aperto

Tipo: Versione (PDF) editoriale / Version Of Record
Licenza: Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY)
Dimensione 675.21 kB
Formato Adobe PDF
675.21 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/1018552
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 2
social impact