Tiny patient, big challenge: pancreatic heterotopia causing ileo-ileal intussusception in an infant

Background Intussusception is a common cause of intestinal obstruction in children, typically occurring between 6 months and 3 years of age. While most cases are idiopathic, rare cases involve pathological lead points. Ileo-ileal intussusception is an uncommon variant, often associated with anomalies such as heterotopic pancreatic tissue. Case Presentation We report a rare case of a 2-month-old infant presenting with inconsolable crying and feeding refusal, diagnosed with ileo-ileal intussusception due to pancreatic heterotopia. Ultrasound confirmed the diagnosis, leading to successful surgical resection of the affected ileal segment, with an uneventful recovery. Conclusion This case emphasizes the importance of considering intussusception in younger infants with nonspecific symptoms. Early imaging, particularly ultrasound, plays a critical role in timely diagnosis. Though rare, pancreatic heterotopia can act as a pathological lead point, highlighting the need for awareness and prompt surgical intervention to optimize pediatric patient outcomes.