: Hyaluronic acid fillers are widely employed for aesthetic procedures but can lead to vascular complications, including rare instances of arterial occlusion. We report a case of columellar artery occlusion following a nasal filler injection in a 30-year-old woman. The patient initially presented with subtle symptoms, including persistent rhinorrhoea and an unusual sensation of cold air. Rhinoscopy revealed full-thickness necrosis of the anterior nasal septum, likely due to compression or embolization of the septal branch of the superior labial artery; prompt treatment with hyaluronidase, aspirin, and topical antibiotics resulted in complete resolution. A literature review identified only one similar case, emphasizing this complication's rarity and potential underreporting. This case underscores the importance of early recognition and intervention in filler-induced vascular events.
Zengarini, C., Sapigni, C., Benati, M., D'Agostino, G., Piraccini, B.M., Melandri, D., et al. (2025). An out-of-season cold. Filler-induced vascular occlusion of the columellar artery causing necrosis of the cartilaginous anterior nasal septum: case report and a literature review. DERMATOLOGY REPORTS, 17(1), 1-2 [10.4081/dr.2024.10061].
An out-of-season cold. Filler-induced vascular occlusion of the columellar artery causing necrosis of the cartilaginous anterior nasal septum: case report and a literature review
Zengarini, Corrado;Piraccini, Bianca Maria;Melandri, Davide;
2025
Abstract
: Hyaluronic acid fillers are widely employed for aesthetic procedures but can lead to vascular complications, including rare instances of arterial occlusion. We report a case of columellar artery occlusion following a nasal filler injection in a 30-year-old woman. The patient initially presented with subtle symptoms, including persistent rhinorrhoea and an unusual sensation of cold air. Rhinoscopy revealed full-thickness necrosis of the anterior nasal septum, likely due to compression or embolization of the septal branch of the superior labial artery; prompt treatment with hyaluronidase, aspirin, and topical antibiotics resulted in complete resolution. A literature review identified only one similar case, emphasizing this complication's rarity and potential underreporting. This case underscores the importance of early recognition and intervention in filler-induced vascular events.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


