Editorial: Omics approaches to delineate the role of gut microbiota-derived metabolites in obesity and metabolic disorders

Obesity is a complex chronic disorder with a multifactorial etiology that involves genetics, hormones, diet, and environmental stimuli (1). It is considered a medical condition that may trigger complications, such as metabolic syndrome, high blood pressure, insulin resistance, low-grade inflammation, heart disease, diabetes, cancer and fatty liver disease. The gut microbiota is implicated in the pathophysiology of obesity and its associated metabolic disorders (2). In this context,-omics approaches can elucidate molecular signatures related to overweight and obesity phenotypes at the cellular level, and underpin the relationship between the gut microbiota at the family, genus or species level and host metabolism (3). On these grounds, this Research Topic aims to elucidate the contribution of-omics approaches in framing fluctuations of gut microbiota-derived metabolites in relation to obesity. Additionally, it provides an overview of the pathogenesis of this condition and outlines plausible risk factors that may trigger the onset of metabolic disorders. The selected articles published in this Research Topic include four research articles and one review.