Editorial: Interaction between the gut flora and immunity in intestinal diseases

It is widely recognized that the gut microbiota influences the host’s health, especially concerning immune homeostasis. The microbiome plays critical roles in the training and development of major components of innate and adaptive immune systems, with immunity regulating the equilibrium of the host-microbe relationship. Comprehending the symbiotic relationship between the gut microbiota and our immune system is crucial for both the discipline of immunology and for gaining insights into the pathogenesis of intestinal diseases. Gut microbiota disruptions are associated with a range of intestinal diseases, including immunological diseases inflammatory bowel disease (IBD) consists of two major subtypes, Crohn’s disease (CD) and ulcerative colitis (UC) (1); irritable bowel syndrome (IBS)and colorectal cancer (CRC) (2, 3).