A field isolate of Encephalomyocarditis (EMC) virus was inoculated intravenously into 8 pigs. Four animals died at post inoculation day (PID) 2, the remaining being sacrificed at PID 5, 7, 11 and 15. Two control, in‐contact pigs were sacrificed at PID 19. Virus was isolated from leucocytes and nasal swabs until PID 4, from rectal swabs until PID 2 and, in the pigs found dead at PID 2, from several organs. EMC virus was further isolated from brain and spleen of the pig sacrificed at PID 7. One of the 2 control pigs became infected: virus was isolated from nasal swabs at days 6 and 7 and from leucocytes at day 4 of the experiment. Serumneutralizing (SN) antibody was detected in the injected pigs starting from PID 4; two days later, it was also revealed in the infected, in‐contact control. To our knowledge, this is the first report of an experimental transmission of EMC virus infection in pigs by contact exposure. © 1993 Blackwell Verlag GmbH
Foni, E., Barigazzi, G., Sidoli, L., Marcato, P.S., Sarli, G., Salda, L.D., et al. (1993). Experimental Encephalomyocarditis Virus Infection in Pigs. JOURNAL OF VETERINARY MEDICINE. SERIES B, 40(1-10), 347-352 [10.1111/j.1439-0450.1993.tb00149.x].
Experimental Encephalomyocarditis Virus Infection in Pigs
Marcato P. S.;Sarli G.;Spinaci M.
1993
Abstract
A field isolate of Encephalomyocarditis (EMC) virus was inoculated intravenously into 8 pigs. Four animals died at post inoculation day (PID) 2, the remaining being sacrificed at PID 5, 7, 11 and 15. Two control, in‐contact pigs were sacrificed at PID 19. Virus was isolated from leucocytes and nasal swabs until PID 4, from rectal swabs until PID 2 and, in the pigs found dead at PID 2, from several organs. EMC virus was further isolated from brain and spleen of the pig sacrificed at PID 7. One of the 2 control pigs became infected: virus was isolated from nasal swabs at days 6 and 7 and from leucocytes at day 4 of the experiment. Serumneutralizing (SN) antibody was detected in the injected pigs starting from PID 4; two days later, it was also revealed in the infected, in‐contact control. To our knowledge, this is the first report of an experimental transmission of EMC virus infection in pigs by contact exposure. © 1993 Blackwell Verlag GmbHI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
