The conditions referred to as ‘spongiform encephalopathies', ‘transmissible spongiform encephalopathies (TSE)' and ‘prion diseases' have been recognised to be conformational diseases in which the prion protein (PrP) adopts a non-native conformation.179,180,376,429,431 This structural change leads to the aggregation of misfolded PrP (mfPrP). Diseases that result from these alterations are today referred to as proteopathies or proteinopathies; for this reason, the nomenclature used in this chapter refers to these specific diseases as PrP proteinopathies.517

Parchi, P., Kovacs, G.G., Baiardi, S., Knight, R., Ghetti, B. (2024). PrP proteinopathies. Boca Raton, Florida : CRC Press [10.1201/9781003389699-31].

PrP proteinopathies

Parchi P.;Baiardi S.;
2024

Abstract

The conditions referred to as ‘spongiform encephalopathies', ‘transmissible spongiform encephalopathies (TSE)' and ‘prion diseases' have been recognised to be conformational diseases in which the prion protein (PrP) adopts a non-native conformation.179,180,376,429,431 This structural change leads to the aggregation of misfolded PrP (mfPrP). Diseases that result from these alterations are today referred to as proteopathies or proteinopathies; for this reason, the nomenclature used in this chapter refers to these specific diseases as PrP proteinopathies.517
2024
Greenfield's Neuropathology, Tenth Edition: Volume 1-2
937
1011
Parchi, P., Kovacs, G.G., Baiardi, S., Knight, R., Ghetti, B. (2024). PrP proteinopathies. Boca Raton, Florida : CRC Press [10.1201/9781003389699-31].
Parchi, P.; Kovacs, G. G.; Baiardi, S.; Knight, R.; Ghetti, B.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/1010671
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