Intestinal microbiota is essential for gut homeostasis. Specifically, the microorganisms inhabiting the gut lumen interact with the intestinal immune system, supply key nutrients for the major components of the gut wall, and modulate energy metabolism. Host-microbiome interactions can be either beneficial or deleterious, driving gastrointestinal lymphoid tissue activities and shaping gut wall structures. This overview briefly focuses on the potential role played by abnormalities in gut microbiota and relative responses of the gastrointestinal tract in the determination of important pathological conditions such as the irritable bowel syndrome, inflammatory bowel diseases and colorectal cancer.
Stanghellini V, Barbara G, Cremon C, Cogliandro R, Antonucci A, Gabusi V, et al. (2010). Gut microbiota and related diseases: clinical features. INTERNAL AND EMERGENCY MEDICINE, 5 (S1), 57-63 [10.1007/s11739-010-0451-0].
Gut microbiota and related diseases: clinical features.
STANGHELLINI, VINCENZO;BARBARA, GIOVANNI;CREMON, CESARE;COGLIANDRO, ROSANNA FRANCESCA;ANTONUCCI, ALEXANDRA;GABUSI, VERONICA;FRISONI, CHIARA;DE GIORGIO, ROBERTO;SERRA, MAURO;CORINALDESI, ROBERTO
2010
Abstract
Intestinal microbiota is essential for gut homeostasis. Specifically, the microorganisms inhabiting the gut lumen interact with the intestinal immune system, supply key nutrients for the major components of the gut wall, and modulate energy metabolism. Host-microbiome interactions can be either beneficial or deleterious, driving gastrointestinal lymphoid tissue activities and shaping gut wall structures. This overview briefly focuses on the potential role played by abnormalities in gut microbiota and relative responses of the gastrointestinal tract in the determination of important pathological conditions such as the irritable bowel syndrome, inflammatory bowel diseases and colorectal cancer.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
