Late Recurrence of a Growing Teratoma Syndrome-Like Lesion in a 54-Year-Old Female Patient: A Follow-up Case Report

Growing teratoma syndrome (GTS) is a condition represented by mature teratomas appearing as a retroconversion of immature teratomatous elements to mature elements after administration of chemotherapy. The aim of this paper is to present a peculiar example of a GTS-like syndrome. This short communication is an update for 1 patient previously reported by our team 8 years ago.1 A 56-year-old obese female patient with a history of previous pelvic surgery presented with symptoms of bilateral lower limb edema. A computed tomography investigation was performed that revealed multiple nodules within the pelvis, involving the right and left iliac regions; also, a 7 cm nodule was identified adjacent to the rectum. The patient was diagnosed 21 years prior to the current presentation with an immature teratoma of endometrium with multiple recurrences in the following years involving both the endometrium and the left ovary, in the form of solid mature teratoma, associated with foci of peritoneal gliomatosis. Hysterectomy was not performed.