This case report describes an 83-year-old patient with a history of non-melanoma skin cancer who presented with a violaceous, painless nodule on the neck. Dermoscopic examination and subsequent biopsy revealed a Small/Medium CD4+ T-cell lymphoproliferative disorder (SMPLPD) of the skin. Although excision was initially recommended, the patient opted for treatment with CO2 laser ablation. The procedure had some minor complications but resulted in successful healing. SMPLPDs are a rare skin condition with limited treatment data, and this case suggests that CO2 laser ablation with minimal margins could be a viable alternative for selected patients, reducing bleeding and promoting second-intention healing for small nodules. However, more extensive followup data for SMPLPD cases are needed to understand long-term outcomes better.

Zengarini, C., Guglielmo, A., Mussi, M., Filippini, A., Vaccari, S., Piraccini, B.M., et al. (2024). Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder nodule successfully treated with laser Co2 ablation: a case report and literature review. DERMATOLOGY REPORTS, 16(4), 1-3 [10.4081/dr.2024.9884].

Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder nodule successfully treated with laser Co2 ablation: a case report and literature review

Zengarini, Corrado;Guglielmo, Alba;Mussi, Martina;Filippini, Andrea;Piraccini, Bianca Maria;Pileri, Alessandro
2024

Abstract

This case report describes an 83-year-old patient with a history of non-melanoma skin cancer who presented with a violaceous, painless nodule on the neck. Dermoscopic examination and subsequent biopsy revealed a Small/Medium CD4+ T-cell lymphoproliferative disorder (SMPLPD) of the skin. Although excision was initially recommended, the patient opted for treatment with CO2 laser ablation. The procedure had some minor complications but resulted in successful healing. SMPLPDs are a rare skin condition with limited treatment data, and this case suggests that CO2 laser ablation with minimal margins could be a viable alternative for selected patients, reducing bleeding and promoting second-intention healing for small nodules. However, more extensive followup data for SMPLPD cases are needed to understand long-term outcomes better.
2024
Zengarini, C., Guglielmo, A., Mussi, M., Filippini, A., Vaccari, S., Piraccini, B.M., et al. (2024). Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder nodule successfully treated with laser Co2 ablation: a case report and literature review. DERMATOLOGY REPORTS, 16(4), 1-3 [10.4081/dr.2024.9884].
Zengarini, Corrado; Guglielmo, Alba; Mussi, Martina; Filippini, Andrea; Vaccari, Sabina; Piraccini, Bianca Maria; Pileri, Alessandro
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/1002177
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact