MILAZZO, GIORGIO
MILAZZO, GIORGIO
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Ricercatori a tempo determinato
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma
2021 Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M.
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma
2012 Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R. Wagenaar; Michael R. Green
Aerobic Growth of Rhodococcus aetherivorans BCP1 Using Selected Naphthenic Acids as the Sole Carbon and Energy Sources
2018 Presentato, Alessandro; Cappelletti, Martina; Sansone, Anna; Ferreri, Carla; Piacenza, Elena; Demeter, Marc A.; Crognale, Silvia; Petruccioli, Maurizio; Milazzo, Giorgio; Fedi, Stefano; Steinbüchel, Alexander; Turner, Raymond J.; Zannoni, Davide
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming
2021 Tao L.; Moreno-Smith M.; Ibarra-Garcia-Padilla R.; Milazzo G.; Drolet N.A.; Hernandez B.E.; Oh Y.S.; Patel I.; Kim J.J.; Zorman B.; Patel T.; Kamal A.H.M.; Zhao Y.; Hicks J.; Vasudevan S.A.; Putluri N.; Coarfa C.; Sumazin P.; Perini G.; Parchem R.J.; Uribe R.A.; Barbieri E.
Contribution of CACNA1H variants in Autism Spectrum Disorder Susceptibility
2022 Marta Viggiano, Tiziano D’Andrea, Cinzia Cameli, Annio Posar, Paola Visconti, Maria Cristina Scaduto, Roberta Colucci, Fabiola Ceroni, Giorgio Milazzo, Sergio Fucile, Elena Maestrini, Elena Bacchelli
Contribution of CACNA1H Variants in Autism Spectrum Disorder Susceptibility
2022 Viggiano, Marta; D'Andrea, Tiziano; Cameli, Cinzia; Posar, Annio; Visconti, Paola; Scaduto, Maria Cristina; Colucci, Roberta; Rochat, Magali J.; Ceroni, Fabiola; Milazzo, Giorgio; Fucile, Sergio; Maestrini, Elena; Bacchelli, Elena
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface
2019 Koach, Jessica; Holien, Jessica K; Massudi, Hassina; Carter, Daniel R; Ciampa, Olivia C; Herath, Mika; Lim, Taylor; Seneviratne, Janith A; Milazzo, Giorgio; Murray, Jayne E; McCarroll, Joshua A; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W; Gorman, Michael A; Bell, Jessica L; Doughty, Larissa; Hüttelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W Clay; Haber, Michelle; Norris, Murray D; Fletcher, Jamie I; Perini, Giovanni; Parker, Michael W; Cheung, Belamy B; Marshall, Glenn M
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression
2014 Liu, Pei Y.; Erriquez, Daniela; Marshall, Glenn M.; Tee, Andrew E.; Polly, Patsie; Wong, Mathew; Liu, Bing; Bell, Jessica L.; Zhang, Xu D.; Milazzo, Giorgio; Cheung, Belamy B.; Fox, Archa; Swarbrick, Alexander; Hüttelmaier, Stefan; Kavallaris, Maria; Perini, Giovanni; Mattick, John S.; Dinger, Marcel E.; Liu, Tao
Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: new metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes
2015 Martina Cappelletti;Alessandro Presentato;Giorgio Milazzo;Raymond J. Turner;Stefano Fedi;Dario Frascari;Davide Zannoni
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability
2020 Milazzo G.; Mercatelli D.; Di Muzio G.; Triboli L.; De Rosa P.; Perini G.; Giorgi F.M.
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
2019 Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M. T. Yu, Kimberley M. Hanssen, Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, Andre Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, and Michelle Haber
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma
2019 Wong M.; Sun Y.; Xi Z.; Milazzo G.; Poulos R.C.; Bartenhagen C.; Bell J.L.; Mayoh C.; Ho N.; Tee A.E.; Chen X.; Li Y.; Ciaccio R.; Liu P.Y.; Jiang C.C.; Lan Q.; Jayatilleke N.; Cheung B.B.; Haber M.; Norris M.D.; Zhang X.D.; Marshall G.M.; Wang J.Y.; Huttelmaier S.; Fischer M.; Wong J.W.H.; Xu H.; Perini G.; Dong Q.; George R.E.; Liu T.
Letting the breaks off MYCN
2016 Perini, Giovanni; Milazzo, Giorgio; Narayan, Nisha; Ekert, Paul G
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma
2015 Amente, Stefano; Milazzo, Giorgio; Sorrentino, Maria Cristina; Ambrosio, Susanna; Di Palo, Giacomo; Lania, Luigi; Perini, Giovanni; Majello, Barbara
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma
2018 Ferrucci, Francesca; Ciaccio, Roberto; Monticelli, Sara; Pigini, Paolo; di Giacomo, Simone; Purgato, Stefania; Erriquez, Daniela; Bernardoni, Roberto; Norris, Murray; Haber, Michelle; Milazzo, Giorgio; Perini, Giovanni
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma
2018 Agarwal, Saurabh; Milazzo, Giorgio; Rajapakshe, Kimal; Bernardi, Ronald; Chen, Zaowen; Barberi, Eveline; Koster, Jan; Perini, Giovanni; Coarfa, Cristian; Shohet, Jason M.*
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
2016 Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D; Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
2022 Tao L.; Mohammad M.A.; Milazzo G.; Moreno-Smith M.; Patel T.D.; Zorman B.; Badachhape A.; Hernandez B.E.; Wolf A.B.; Zeng Z.; Foster J.H.; Aloisi S.; Sumazin P.; Zu Y.; Hicks J.; Ghaghada K.B.; Putluri N.; Perini G.; Coarfa C.; Barbieri E.
Restoration of the molecular clock is tumor suppressive in neuroblastoma
2021 Moreno-Smith M.; Milazzo G.; Tao L.; Fekry B.; Zhu B.; Mohammad M.A.; Di Giacomo S.; Borkar R.; Reddy K.R.K.; Capasso M.; Vasudevan S.A.; Sumazin P.; Hicks J.; Putluri N.; Perini G.; Eckel-Mahan K.; Burris T.P.; Barbieri E.
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells
2022 Milazzo G.; Perini G.; Giorgi F.M.
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma | Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli... E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M. | 2021-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-13-01807-v2.pdf |
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma | Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R.... Wagenaar; Michael R. Green | 2012-01-01 | - | - | 4.03 Poster | - |
Aerobic Growth of Rhodococcus aetherivorans BCP1 Using Selected Naphthenic Acids as the Sole Carbon and Energy Sources | Presentato, Alessandro; Cappelletti, Martina; Sansone, Anna; Ferreri, Carla; Piacenza, Elena; Dem...eter, Marc A.; Crognale, Silvia; Petruccioli, Maurizio; Milazzo, Giorgio; Fedi, Stefano; Steinbüchel, Alexander; Turner, Raymond J.; Zannoni, Davide | 2018-01-01 | FRONTIERS IN MICROBIOLOGY | - | 1.01 Articolo in rivista | fmicb-09-00672-1.pdf |
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming | Tao L.; Moreno-Smith M.; Ibarra-Garcia-Padilla R.; Milazzo G.; Drolet N.A.; Hernandez B.E.; Oh Y....S.; Patel I.; Kim J.J.; Zorman B.; Patel T.; Kamal A.H.M.; Zhao Y.; Hicks J.; Vasudevan S.A.; Putluri N.; Coarfa C.; Sumazin P.; Perini G.; Parchem R.J.; Uribe R.A.; Barbieri E. | 2021-01-01 | ADVANCED SCIENCE | - | 1.01 Articolo in rivista | Tao L et al.pdf |
Contribution of CACNA1H variants in Autism Spectrum Disorder Susceptibility |
Marta Viggiano, Tiziano D’Andrea, Cinzia Cameli, Annio Posar, Paola Visconti, Maria Cristina Scad...uto, Roberta Colucci, Fabiola Ceroni, Giorgio Milazzo, Sergio Fucile, Elena Maestrini, Elena Bacchelli |
2022-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
Contribution of CACNA1H Variants in Autism Spectrum Disorder Susceptibility | Viggiano, Marta; D'Andrea, Tiziano; Cameli, Cinzia; Posar, Annio; Visconti, Paola; Scaduto, Maria... Cristina; Colucci, Roberta; Rochat, Magali J.; Ceroni, Fabiola; Milazzo, Giorgio; Fucile, Sergio; Maestrini, Elena; Bacchelli, Elena | 2022-01-01 | FRONTIERS IN PSYCHIATRY | - | 1.01 Articolo in rivista | Viggiano et al.pdf |
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface | Koach, Jessica; Holien, Jessica K; Massudi, Hassina; Carter, Daniel R; Ciampa, Olivia C; Herath, ...Mika; Lim, Taylor; Seneviratne, Janith A; Milazzo, Giorgio; Murray, Jayne E; McCarroll, Joshua A; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W; Gorman, Michael A; Bell, Jessica L; Doughty, Larissa; Hüttelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W Clay; Haber, Michelle; Norris, Murray D; Fletcher, Jamie I; Perini, Giovanni; Parker, Michael W; Cheung, Belamy B; Marshall, Glenn M | 2019-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression | Liu, Pei Y.; Erriquez, Daniela; Marshall, Glenn M.; Tee, Andrew E.; Polly, Patsie; Wong, Mathew; ...Liu, Bing; Bell, Jessica L.; Zhang, Xu D.; Milazzo, Giorgio; Cheung, Belamy B.; Fox, Archa; Swarbrick, Alexander; Hüttelmaier, Stefan; Kavallaris, Maria; Perini, Giovanni; Mattick, John S.; Dinger, Marcel E.; Liu, Tao | 2014-01-01 | JOURNAL OF THE NATIONAL CANCER INSTITUTE | - | 1.01 Articolo in rivista | - |
Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: new metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes | Martina Cappelletti;Alessandro Presentato;Giorgio Milazzo;Raymond J. Turner;Stefano Fedi;Dario Fr...ascari;Davide Zannoni | 2015-01-01 | FRONTIERS IN MICROBIOLOGY | - | 1.01 Articolo in rivista | - |
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability | Milazzo G.; Mercatelli D.; Di Muzio G.; Triboli L.; De Rosa P.; Perini G.; Giorgi F.M. | 2020-01-01 | GENES | - | 1.01 Articolo in rivista | genes-11-00556-v2_compressed.pdf |
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma | Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M. T. Yu, Kimberley M. Hanssen,... Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, Andre Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, and Michelle Haber | 2019-01-01 | SCIENCE TRANSLATIONAL MEDICINE | - | 1.01 Articolo in rivista | - |
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma | Wong M.; Sun Y.; Xi Z.; Milazzo G.; Poulos R.C.; Bartenhagen C.; Bell J.L.; Mayoh C.; Ho N.; Tee ...A.E.; Chen X.; Li Y.; Ciaccio R.; Liu P.Y.; Jiang C.C.; Lan Q.; Jayatilleke N.; Cheung B.B.; Haber M.; Norris M.D.; Zhang X.D.; Marshall G.M.; Wang J.Y.; Huttelmaier S.; Fischer M.; Wong J.W.H.; Xu H.; Perini G.; Dong Q.; George R.E.; Liu T. | 2019-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.pdf |
Letting the breaks off MYCN | Perini, Giovanni; Milazzo, Giorgio; Narayan, Nisha; Ekert, Paul G | 2016-01-01 | CELL DEATH AND DIFFERENTIATION | - | 1.01 Articolo in rivista | - |
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma | Amente, Stefano; Milazzo, Giorgio; Sorrentino, Maria Cristina; Ambrosio, Susanna; Di Palo, Giacom...o; Lania, Luigi; Perini, Giovanni; Majello, Barbara | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | Milazzo,Perini-oncotarget-v6i16-3990.pdf |
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma | Ferrucci, Francesca; Ciaccio, Roberto; Monticelli, Sara; Pigini, Paolo; di Giacomo, Simone; Purga...to, Stefania; Erriquez, Daniela; Bernardoni, Roberto; Norris, Murray; Haber, Michelle; Milazzo, Giorgio; Perini, Giovanni | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA | - | 1.01 Articolo in rivista | - |
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma | Agarwal, Saurabh; Milazzo, Giorgio; Rajapakshe, Kimal; Bernardi, Ronald; Chen, Zaowen; Barberi, E...veline; Koster, Jan; Perini, Giovanni; Coarfa, Cristian; Shohet, Jason M.* | 2018-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 | Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laur...a; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D; Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D | 2016-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma | Tao L.; Mohammad M.A.; Milazzo G.; Moreno-Smith M.; Patel T.D.; Zorman B.; Badachhape A.; Hernand...ez B.E.; Wolf A.B.; Zeng Z.; Foster J.H.; Aloisi S.; Sumazin P.; Zu Y.; Hicks J.; Ghaghada K.B.; Putluri N.; Perini G.; Coarfa C.; Barbieri E. | 2022-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | - |
Restoration of the molecular clock is tumor suppressive in neuroblastoma | Moreno-Smith M.; Milazzo G.; Tao L.; Fekry B.; Zhu B.; Mohammad M.A.; Di Giacomo S.; Borkar R.; R...eddy K.R.K.; Capasso M.; Vasudevan S.A.; Sumazin P.; Hicks J.; Putluri N.; Perini G.; Eckel-Mahan K.; Burris T.P.; Barbieri E. | 2021-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | Myrthala Moreno-Smith et al.pdf |
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells | Milazzo G.; Perini G.; Giorgi F.M. | 2022-01-01 | GENES | - | 1.01 Articolo in rivista | - |