KURELAC, IVANA
KURELAC, IVANA
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Ricercatori a tempo determinato
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder
2012-01-01 Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M.
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis
2021-01-01 Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana
Coenzyme Q10 depletion induces endogenous hypoxia in cultured cells
2018-01-01 Liparulo, Irene; Bergamini, Christian; Wenping, Wang; Masin, Luca; Rizzardi, Nicola; Kurelac, Ivana; Gasparre, Giuseppe; Bortolus, Marco; Romana, Fato
Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes.
2013-01-01 Iommarini L.; Calvaruso M.A.; Kurelac I.; Gasparre G.; Porcelli A.M.
A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme
2015-01-01 Michele Vidone;Rosanna Clima;Mariangela Santorsola;Claudia Calabrese;Giulia Girolimetti;Ivana Kurelac;Laura Benedetta Amato;Luisa Iommarini;Elisa Trevisan;Marco Leone;Riccardo Soffietti;Isabella Morra;Giuliano Faccani;Marcella Attimonelli;Anna Maria Porcelli;Giuseppe Gasparre
Current methodologies to detect circulating tumor cells: a focus on ovarian cancer
2021-01-01 Lemma, Silvia; Perrone, Anna M; De Iaco, Pierandrea; Gasparre, Giuseppe; Kurelac, Ivana
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
2014-01-01 L. Iommarini;I. Kurelac;M. Capristo;M. A. Calvaruso;V. Giorgio;C. Bergamini;A. Ghelli;P. Nanni;C. De Giovanni;V. Carelli;R. Fato;P. L. Lollini;M. Rugolo;G. Gasparre;A. M. Porcelli
Evidence of association of human papillomavirus with prognosis worsening in glioblastoma multiforme
2014-01-01 M. Vidone;F. Alessandrini;G. Marucci;A. Farnedi;D. de Biase;F. Ricceri;C. Calabrese;I. Kurelac;A. M. Porcelli;M. Cricca;G. Gasparre
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.
2013-01-01 Bartoletti-Stella A;Mariani E;Kurelac I;Maresca A;Caratozzolo MF;Iommarini L;Carelli V;Eusebi LH;Guido A;Cenacchi G;Fuccio L;Rugolo M;Tullo A;Porcelli AM;Gasparre G
Generation of neighbor-labeling cells to study intercellular interactions in vivo
2021-01-01 Ombrato, Luigi; Nolan, Emma; Passaro, Diana; Kurelac, Ivana; Bridgeman, Victoria L; Waclawiczek, Alexander; Duarte, Delfim; Lo Celso, Cristina; Bonnet, Dominique; Malanchi, Ilaria
Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology
2012-01-01 F.C. Geyer; D. de Biase; M.B.K. Lambros; M. Ragazzi; M.A. Lopez-Garcia; R. Natrajan; A. Mackay; I. Kurelac; G. Gasparre; A. Ashworth; V. Eusebi; J.S. Reis-Filho; G. Tallini
High-resolution genomic profiling of thyroid lesions uncovers preferential copy number gains affecting mitochondrial biogenesis loci in the oncocytic variants
2015-01-01 Kurelac, Ivana; de Biase, Dario; Calabrese, Claudia; Ceccarelli, Claudio; Ng, Charlotte Ky; Lim, Raymond; Mackay, Alan; Weigelt, Britta; Porcelli, Anna Maria; Reis-Filho, Jorge S; Tallini, Giovanni; Gasparre, Giuseppe
Human papillomavirus infection and pathogenic mitochondrial DNA mutation in bilateral multinodular oncocytic hyperplasia of the parotid
2014-01-01 Ivana Kurelac;Nunzio Cosimo Salfi;Claudio Ceccarelli;Federica Alessandrini;Monica Cricca;Umberto Caliceti;Giuseppe Gasparre
A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma
2019-01-01 Kurelac, Ivana; Abarrategi, Ander; Ragazzi, Moira; Iommarini, Luisa; Umesh Ganesh, Nikkitha; Snoeks, Thomas; Bonnet, Dominique; Porcelli, Anna Maria; Malanchi, Ilaria; Gasparre, Giuseppe
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses
2019-01-01 Kurelac, Ivana; Iommarini, Luisa; Vatrinet, Renaud; Amato, Laura Benedetta; De Luise, Monica; Leone, Giulia; Girolimetti, Giulia; Umesh Ganesh, Nikkitha; Bridgeman, Victoria Louise; Ombrato, Luigi; Columbaro, Marta; Ragazzi, Moira; Gibellini, Lara; Sollazzo, Manuela; Feichtinger, Rene Gunther; Vidali, Silvia; Baldassarre, Maurizio; Foriel, Sarah; Vidone, Michele; Cossarizza, Andrea; Grifoni, Daniela; Kofler, Barbara; Malanchi, Ilaria; Porcelli, Anna Maria; Gasparre, Giuseppe
Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer
2022-01-01 De Luise, Monica; Sollazzo, Manuela; Lama, Eleonora; Coadă, Camelia Alexandra; Bressi, Licia; Iorio, Maria; Cavina, Beatrice; D’Angelo, Luigi; Milioni, Sara; Marchio, Lorena; Miglietta, Stefano; Coluccelli, Sara; Tedesco, Greta; Ghelli, Anna; Lemma, Silvia; Perrone, Anna Myriam; Kurelac, Ivana; Iommarini, Luisa; Porcelli, Anna Maria; Gasparre, Giuseppe
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
2009-01-01 G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli.
Metastatic-niche labelling reveals parenchymal cells with stem features
2019-01-01 Ombrato L.; Nolan E.; Kurelac I.; Mavousian A.; Bridgeman V.L.; Heinze I.; Chakravarty P.; Horswell S.; Gonzalez-Gualda E.; Matacchione G.; Weston A.; Kirkpatrick J.; Husain E.; Speirs V.; Collinson L.; Ori A.; Lee J.-H.; Malanchi I.
Mild phenotypes and proper supercomplex assembly in human cells carrying the homoplasmic m.15557G > A mutation in cytochrome b gene
2018-01-01 Iommarini, Luisa; Ghelli, Anna; Leone, Giulia; Tropeano, Concetta Valentina; Kurelac, Ivana; Amato, Laura Benedetta; Gasparre, Giuseppe; Porcelli, Anna Maria
Mitochondrial DNA genotyping efficiently reveals clonality of synchronous endometrial and ovarian cancers
2014-01-01 Flora Guerra;Giulia Girolimetti;Anna Myriam Perrone;Martina Procaccini;Ivana Kurelac;Claudio Ceccarelli;Dario De Biase;Giacomo Caprara;Claudio Zamagni;Pierandrea De Iaco;Donatella Santini;Giuseppe Gasparre
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder | Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis | Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana | 2021-01-01 | THE FEBS JOURNAL | - | 1.01 Articolo in rivista | - |
| Coenzyme Q10 depletion induces endogenous hypoxia in cultured cells | Liparulo, Irene; Bergamini, Christian; Wenping, Wang; Masin, Luca; Rizzardi, Nicola; Kurelac, Ivana; Gasparre, Giuseppe; Bortolus, Marco; Romana, Fato | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes. | Iommarini L.; Calvaruso M.A.; Kurelac I.; Gasparre G.; Porcelli A.M. | 2013-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme | Michele Vidone;Rosanna Clima;Mariangela Santorsola;Claudia Calabrese;Giulia Girolimetti;Ivana Kurelac;Laura Benedetta Amato;Luisa Iommarini;Elisa Trevisan;Marco Leone;Riccardo Soffietti;Isabella Morra;Giuliano Faccani;Marcella Attimonelli;Anna Maria Porcelli;Giuseppe Gasparre | 2015-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| Current methodologies to detect circulating tumor cells: a focus on ovarian cancer | Lemma, Silvia; Perrone, Anna M; De Iaco, Pierandrea; Gasparre, Giuseppe; Kurelac, Ivana | 2021-01-01 | AMERICAN JOURNAL OF CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment | L. Iommarini;I. Kurelac;M. Capristo;M. A. Calvaruso;V. Giorgio;C. Bergamini;A. Ghelli;P. Nanni;C. De Giovanni;V. Carelli;R. Fato;P. L. Lollini;M. Rugolo;G. Gasparre;A. M. Porcelli | 2014-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Evidence of association of human papillomavirus with prognosis worsening in glioblastoma multiforme | M. Vidone;F. Alessandrini;G. Marucci;A. Farnedi;D. de Biase;F. Ricceri;C. Calabrese;I. Kurelac;A. M. Porcelli;M. Cricca;G. Gasparre | 2014-01-01 | NEURO-ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. | Bartoletti-Stella A;Mariani E;Kurelac I;Maresca A;Caratozzolo MF;Iommarini L;Carelli V;Eusebi LH;Guido A;Cenacchi G;Fuccio L;Rugolo M;Tullo A;Porcelli AM;Gasparre G | 2013-01-01 | CELL DEATH & DISEASE | - | 1.01 Articolo in rivista | cddis2013187.pdf |
| Generation of neighbor-labeling cells to study intercellular interactions in vivo | Ombrato, Luigi; Nolan, Emma; Passaro, Diana; Kurelac, Ivana; Bridgeman, Victoria L; Waclawiczek, Alexander; Duarte, Delfim; Lo Celso, Cristina; Bonnet, Dominique; Malanchi, Ilaria | 2021-01-01 | NATURE PROTOCOLS | - | 1.01 Articolo in rivista | - |
| Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology | F.C. Geyer; D. de Biase; M.B.K. Lambros; M. Ragazzi; M.A. Lopez-Garcia; R. Natrajan; A. Mackay; I. Kurelac; G. Gasparre; A. Ashworth; V. Eusebi; J.S. Reis-Filho; G. Tallini | 2012-01-01 | BREAST CANCER RESEARCH AND TREATMENT | - | 1.01 Articolo in rivista | - |
| High-resolution genomic profiling of thyroid lesions uncovers preferential copy number gains affecting mitochondrial biogenesis loci in the oncocytic variants | Kurelac, Ivana; de Biase, Dario; Calabrese, Claudia; Ceccarelli, Claudio; Ng, Charlotte Ky; Lim, Raymond; Mackay, Alan; Weigelt, Britta; Porcelli, Anna Maria; Reis-Filho, Jorge S; Tallini, Giovanni; Gasparre, Giuseppe | 2015-01-01 | AMERICAN JOURNAL OF CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Human papillomavirus infection and pathogenic mitochondrial DNA mutation in bilateral multinodular oncocytic hyperplasia of the parotid | Ivana Kurelac;Nunzio Cosimo Salfi;Claudio Ceccarelli;Federica Alessandrini;Monica Cricca;Umberto Caliceti;Giuseppe Gasparre | 2014-01-01 | PATHOLOGY | - | 1.01 Articolo in rivista | - |
| A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma | Kurelac, Ivana; Abarrategi, Ander; Ragazzi, Moira; Iommarini, Luisa; Umesh Ganesh, Nikkitha; Snoeks, Thomas; Bonnet, Dominique; Porcelli, Anna Maria; Malanchi, Ilaria; Gasparre, Giuseppe | 2019-01-01 | JOURNAL OF CLINICAL MEDICINE | - | 1.01 Articolo in rivista | jcm-08-02184.pdf |
| Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses | Kurelac, Ivana; Iommarini, Luisa; Vatrinet, Renaud; Amato, Laura Benedetta; De Luise, Monica; Leone, Giulia; Girolimetti, Giulia; Umesh Ganesh, Nikkitha; Bridgeman, Victoria Louise; Ombrato, Luigi; Columbaro, Marta; Ragazzi, Moira; Gibellini, Lara; Sollazzo, Manuela; Feichtinger, Rene Gunther; Vidali, Silvia; Baldassarre, Maurizio; Foriel, Sarah; Vidone, Michele; Cossarizza, Andrea; Grifoni, Daniela; Kofler, Barbara; Malanchi, Ilaria; Porcelli, Anna Maria; Gasparre, Giuseppe | 2019-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | Kurelac et al 2019.pdf; 41467_2019_8839_MOESM1_ESM.pdf; 41467_2019_8839_MOESM2_ESM.pdf; 41467_2019_8839_MOESM3_ESM.pdf |
| Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer | De Luise, Monica; Sollazzo, Manuela; Lama, Eleonora; Coadă, Camelia Alexandra; Bressi, Licia; Iorio, Maria; Cavina, Beatrice; D’Angelo, Luigi; Milioni, Sara; Marchio, Lorena; Miglietta, Stefano; Coluccelli, Sara; Tedesco, Greta; Ghelli, Anna; Lemma, Silvia; Perrone, Anna Myriam; Kurelac, Ivana; Iommarini, Luisa; Porcelli, Anna Maria; Gasparre, Giuseppe | 2022-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | Sci Rep.pdf |
| An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. | G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli. | 2009-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| Metastatic-niche labelling reveals parenchymal cells with stem features | Ombrato L.; Nolan E.; Kurelac I.; Mavousian A.; Bridgeman V.L.; Heinze I.; Chakravarty P.; Horswell S.; Gonzalez-Gualda E.; Matacchione G.; Weston A.; Kirkpatrick J.; Husain E.; Speirs V.; Collinson L.; Ori A.; Lee J.-H.; Malanchi I. | 2019-01-01 | NATURE | - | 1.01 Articolo in rivista | Ombrato_AM.pdf; 41586_2019_1487_MOESM3_ESM.xlsx; 41586_2019_1487_MOESM4_ESM.xlsx |
| Mild phenotypes and proper supercomplex assembly in human cells carrying the homoplasmic m.15557G > A mutation in cytochrome b gene | Iommarini, Luisa; Ghelli, Anna; Leone, Giulia; Tropeano, Concetta Valentina; Kurelac, Ivana; Amato, Laura Benedetta; Gasparre, Giuseppe; Porcelli, Anna Maria | 2018-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| Mitochondrial DNA genotyping efficiently reveals clonality of synchronous endometrial and ovarian cancers | Flora Guerra;Giulia Girolimetti;Anna Myriam Perrone;Martina Procaccini;Ivana Kurelac;Claudio Ceccarelli;Dario De Biase;Giacomo Caprara;Claudio Zamagni;Pierandrea De Iaco;Donatella Santini;Giuseppe Gasparre | 2014-01-01 | MODERN PATHOLOGY | - | 1.01 Articolo in rivista | - |