CICIARELLO, MARILENA
CICIARELLO, MARILENA
DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE (attivo dal 28/10/2011 al 31/12/2022)
Collaboratori
Noncanonical NF-κB signaling in dendritic cells is required for ATP-driven indoleamine 2,3-dioxygenase 1 induction through P2Y11 receptor
2025 Ocadlikova, D.; Fiordi, B.; Trabanelli, S.; Salvestrini, V.; Ciciarello, M.; Forte, D.; Campazzi, E.; Vitali, L.; Cipollitta, S. C.; Pegoraro, A.; Jandus, C.; Di Virgilio, F.; Adinolfi, E.; Cavo, M.; Curti, A.
Ex vivo characterization of acute myeloid leukemia patients undergoing hypomethylating agents and venetoclax regimen reveals a venetoclax-specific effect on non-suppressive regulatory T cells and bona fide PD-1+TIM3+ exhausted CD8+ T cells
2024 Corradi, G.; Forte, D.; Cristiano, G.; Polimeno, A.; Ciciarello, M.; Salvestrini, V.; Bandini, L.; Robustelli, V.; Ottaviani, E.; Cavo, M.; Ocadlikova, D.; Curti, A.
An IDO1-related immune gene signature predicts overall survival in acute myeloid leukemia
2022 Ragaini S.; Wagner S.; Marconi G.; Parisi S.; Sartor C.; Nanni J.; Cristiano G.; Talami A.; Olivi M.; Ocadlikova D.; Ciciarello M.; Corradi G.; Ottaviani E.; Papayannidis C.; Paolini S.; Vadakekolathu J.; Cavo M.; Rutella S.; Curti A.
Release of IFNg by Acute Myeloid Leukemia Cells Remodels Bone Marrow Immune Microenvironment by Inducing Regulatory T Cells
2022 Corradi G.; Bassani B.; Simonetti G.; Sangaletti S.; Vadakekolathu J.; Fontana M.C.; Pazzaglia M.; Gulino A.; Tripodo C.; Cristiano G.; Bandini L.; Ottaviani E.; Ocadlikova D.; Piccioli M.; Martinelli G.; Colombo M.P.; Rutella S.; Cavo M.; Ciciarello M.; Curti A.
Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (Front. Oncol, (2020), 10, (1225), 10.3389/fonc.2020.01225)
2021 Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A.
Emerging bone marrow microenvironment‐driven mechanisms of drug resistance in acute myeloid leukemia: Tangle or chance?
2021 Ciciarello M.; Corradi G.; Forte D.; Cavo M.; Curti A.
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells
2020 Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A.
TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML
2020 Vadakekolathu, Jayakumar; Lai, Catherine; Reeder, Stephen; Church, Sarah E; Hood, Tressa; Lourdusamy, Anbarasu; Rettig, Michael P; Aldoss, Ibrahim; Advani, Anjali S; Godwin, John; Wieduwilt, Matthew J; Arellano, Martha; Muth, John; Yau, Tung On; Ravandi, Farhad; Sweet, Kendra; Altmann, Heidi; Foulds, Gemma A; Stölzel, Friedrich; Middeke, Jan Moritz; Ciciarello, Marilena; Curti, Antonio; Valk, Peter J M; Löwenberg, Bob; Gojo, Ivana; Bornhäuser, Martin; DiPersio, John F; Davidson-Moncada, Jan K; Rutella, Sergio
The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia
2019 Ciciarello, Marilena; Corradi, Giulia; Loscocco, Federica; Visani, Giuseppe; Monaco, Federica; Cavo, Michele; Curti, Antonio; Isidori, Alessandro
Immunosenescence and immunotherapy in elderly acute myeloid leukemia patients: Time for a biology-driven approach
2018 Isidori, Alessandro*; Loscocco, Federica; Ciciarello, Marilena; Corradi, Giulia; Lecciso, Mariangela; Ocadlikova, Darina; Parisi, Sarah; Salvestrini, Valentina; Amadori, Sergio; Visani, Giuseppe; Curti, Antonio
Mesenchymal stromal cells from myelodysplastic and acute myeloid leukemia patients display in vitro reduced proliferative potential and similar capacity to support leukemia cell survival
2018 Corradi, Giulia; Baldazzi, Carmen; Očadlíková, Darina; Marconi, Giovanni; Parisi, Sarah; Testoni, Nicoletta; Finelli, Carlo; Cavo, Michele; Curti, Antonio; Ciciarello, Marilena
Molecular and functional characterization of CD133+stem/progenitor cells infused in patients with end-stage liver disease reveals their interplay with stromal liver cells
2017 Catani, Lucia; Sollazzo, Daria; Bianchi, Elisa; Ciciarello, Marilena; Antoniani, Chiara; Foscoli, Licia; Caraceni, Paolo; Giannone, Ferdinando Antonino; Baldassarre, Maurizio; Giordano, Rosaria; Montemurro, Tiziana; Montelatici, Elisa; D'Errico, Antonia; Andreone, Pietro; Giudice, Valeria; Curti, Antonio; Manfredini, Rossella; Lemoli, Roberto Massimo
The more, the better: "Do the right thing" for natural killer immunotherapy in acute myeloid leukemia
2017 Parisi, Sarah; Lecciso, MARIANGELA STEFANIA; Ocadlikova, Darina; Salvestrini, Valentina; Ciciarello, Marilena; Forte, Dorian; Corradi, Giulia; Cavo, Michele; Curti, Antonio
CD103 marks a subset of human CD34+-derived langerin+ dendritic cells that induce T-regulatory cells via indoleamine 2,3-dioxygenase-1
2015 Ocadlikova, Darina; Trabanelli, Sara; Salvestrini, Valentina; Ciciarello, Marilena; Evangelisti, Cecilia; Lecciso, MARIANGELA STEFANIA; Sabattini, Elena; Righi, Simona; Piccioli, Milena; Pileri, Stefano; Lemoli, ROBERTO MASSIMO; Curti, Antonio
Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn's disease patients in a mouse model of colitis
2015 Forte, Dorian; Ciciarello, Marilena; Valerii, MARIA CHIARA; DE FAZIO, Luigia; Cavazza, Elena; Giordano, Rosaria; Parazzi, Valentina; Lazzari, Lorenza; Laureti, Silvio; Rizzello, Fernando; Cavo, Michele; Curti, Antonio; Lemoli, ROBERTO MASSIMO; Spisni, Enzo; Catani, Lucia
The Human Mesenchymal Stromal Cell-Derived Osteocyte Capacity to Modulate Dendritic Cell Functions Is Strictly Dependent on the Culture System
2015 Trabanelli, Sara; La Manna, Federico; Romano, Marco; Salvestrini, Valentina; Cavo, Michele; Ciciarello, Marilena; Lemoli, Roberto M; Curti, Antonio
Platelet lysate enhances the therapeutic activity of Adipose Derived Mesenchymal stromal cells isolated from Crohn disease patients in a novel Mouse model of Colitis
2014 Dorian Forte; Marilena Ciciarello; Maria Chiara Valerii; Luigia De Fazio; Rosaria Giordano; Elisa Montelatici; Silvio Laureti; Fernando Rizzello; Roberto Massimo Lemoli; Lucia Catani; Enzo Spisni
The role of the immunosuppressive microenvironment in acute myeloid leukemia development and treatment.
2014 Isidori A; Salvestrini V; Ciciarello M; Loscocco F; Visani G; Parisi S; Lecciso M; Ocadlikova D; Rossi L; Gabucci E; Clissa C; Curti A.
The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells.
2014 Trabanelli S; Očadlíková D; Ciciarello M; Salvestrini V; Lecciso M; Jandus C; Metz R; Evangelisti C; Laury-Kleintop L; Romero P; Prendergast GC; Curti A; Lemoli RM.
Extracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages.
2013 Ciciarello M; Zini R; Rossi L; Salvestrini V; Ferrari D; Manfredini R; Lemoli RM.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Noncanonical NF-κB signaling in dendritic cells is required for ATP-driven indoleamine 2,3-dioxygenase 1 induction through P2Y11 receptor | Ocadlikova, D.; Fiordi, B.; Trabanelli, S.; Salvestrini, V.; Ciciarello, M.; Forte, D.; Campazzi,... E.; Vitali, L.; Cipollitta, S. C.; Pegoraro, A.; Jandus, C.; Di Virgilio, F.; Adinolfi, E.; Cavo, M.; Curti, A. | 2025-01-01 | JOURNAL OF LEUKOCYTE BIOLOGY | - | 1.01 Articolo in rivista | qiaf010.pdf; qiaf010_supplementary_data.doc |
| Ex vivo characterization of acute myeloid leukemia patients undergoing hypomethylating agents and venetoclax regimen reveals a venetoclax-specific effect on non-suppressive regulatory T cells and bona fide PD-1+TIM3+ exhausted CD8+ T cells | Corradi, G.; Forte, D.; Cristiano, G.; Polimeno, A.; Ciciarello, M.; Salvestrini, V.; Bandini, L....; Robustelli, V.; Ottaviani, E.; Cavo, M.; Ocadlikova, D.; Curti, A. | 2024-01-01 | FRONTIERS IN IMMUNOLOGY | - | 1.01 Articolo in rivista | fimmu-15-1386517.pdf; Data Sheet 1.doc |
| An IDO1-related immune gene signature predicts overall survival in acute myeloid leukemia | Ragaini S.; Wagner S.; Marconi G.; Parisi S.; Sartor C.; Nanni J.; Cristiano G.; Talami A.; Olivi... M.; Ocadlikova D.; Ciciarello M.; Corradi G.; Ottaviani E.; Papayannidis C.; Paolini S.; Vadakekolathu J.; Cavo M.; Rutella S.; Curti A. | 2022-01-01 | BLOOD ADVANCES | - | 1.01 Articolo in rivista | IDO1 score Ragaini Blood Advances.pdf; advancesADV2021004878-suppl1.pdf |
| Release of IFNg by Acute Myeloid Leukemia Cells Remodels Bone Marrow Immune Microenvironment by Inducing Regulatory T Cells | Corradi G.; Bassani B.; Simonetti G.; Sangaletti S.; Vadakekolathu J.; Fontana M.C.; Pazzaglia M....; Gulino A.; Tripodo C.; Cristiano G.; Bandini L.; Ottaviani E.; Ocadlikova D.; Piccioli M.; Martinelli G.; Colombo M.P.; Rutella S.; Cavo M.; Ciciarello M.; Curti A. | 2022-01-01 | CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (Front. Oncol, (2020), 10, (1225), 10.3389/fonc.2020.01225) | Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.;... De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A. | 2021-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-11-668460 (1).pdf |
| Emerging bone marrow microenvironment‐driven mechanisms of drug resistance in acute myeloid leukemia: Tangle or chance? | Ciciarello M.; Corradi G.; Forte D.; Cavo M.; Curti A. | 2021-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-13-05319-v3.pdf |
| Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells | Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.;... De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A. | 2020-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells.pdf; 5072249.zip |
| TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML | Vadakekolathu, Jayakumar; Lai, Catherine; Reeder, Stephen; Church, Sarah E; Hood, Tressa; Lourdus...amy, Anbarasu; Rettig, Michael P; Aldoss, Ibrahim; Advani, Anjali S; Godwin, John; Wieduwilt, Matthew J; Arellano, Martha; Muth, John; Yau, Tung On; Ravandi, Farhad; Sweet, Kendra; Altmann, Heidi; Foulds, Gemma A; Stölzel, Friedrich; Middeke, Jan Moritz; Ciciarello, Marilena; Curti, Antonio; Valk, Peter J M; Löwenberg, Bob; Gojo, Ivana; Bornhäuser, Martin; DiPersio, John F; Davidson-Moncada, Jan K; Rutella, Sergio | 2020-01-01 | BLOOD ADVANCES | - | 1.01 Articolo in rivista | - |
| The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia | Ciciarello, Marilena; Corradi, Giulia; Loscocco, Federica; Visani, Giuseppe; Monaco, Federica; Ca...vo, Michele; Curti, Antonio; Isidori, Alessandro | 2019-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-09-01135.pdf |
| Immunosenescence and immunotherapy in elderly acute myeloid leukemia patients: Time for a biology-driven approach | Isidori, Alessandro*; Loscocco, Federica; Ciciarello, Marilena; Corradi, Giulia; Lecciso, Mariang...ela; Ocadlikova, Darina; Parisi, Sarah; Salvestrini, Valentina; Amadori, Sergio; Visani, Giuseppe; Curti, Antonio | 2018-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-10-00211.pdf |
| Mesenchymal stromal cells from myelodysplastic and acute myeloid leukemia patients display in vitro reduced proliferative potential and similar capacity to support leukemia cell survival | Corradi, Giulia; Baldazzi, Carmen; Očadlíková, Darina; Marconi, Giovanni; Parisi, Sarah; Testoni,... Nicoletta; Finelli, Carlo; Cavo, Michele; Curti, Antonio; Ciciarello, Marilena | 2018-01-01 | STEM CELL RESEARCH & THERAPY | - | 1.01 Articolo in rivista | stem cell.pdf |
| Molecular and functional characterization of CD133+stem/progenitor cells infused in patients with end-stage liver disease reveals their interplay with stromal liver cells | Catani, Lucia; Sollazzo, Daria; Bianchi, Elisa; Ciciarello, Marilena; Antoniani, Chiara; Foscoli,... Licia; Caraceni, Paolo; Giannone, Ferdinando Antonino; Baldassarre, Maurizio; Giordano, Rosaria; Montemurro, Tiziana; Montelatici, Elisa; D'Errico, Antonia; Andreone, Pietro; Giudice, Valeria; Curti, Antonio; Manfredini, Rossella; Lemoli, Roberto Massimo | 2017-01-01 | CYTOTHERAPY | - | 1.01 Articolo in rivista | - |
| The more, the better: "Do the right thing" for natural killer immunotherapy in acute myeloid leukemia | Parisi, Sarah; Lecciso, MARIANGELA STEFANIA; Ocadlikova, Darina; Salvestrini, Valentina; Ciciarel...lo, Marilena; Forte, Dorian; Corradi, Giulia; Cavo, Michele; Curti, Antonio | 2017-01-01 | FRONTIERS IN IMMUNOLOGY | - | 1.01 Articolo in rivista | Parisi_et_al-2017-Frontiers_in_Immunology.pdf |
| CD103 marks a subset of human CD34<sup>+</sup>-derived langerin<sup>+</sup> dendritic cells that induce T-regulatory cells via indoleamine 2,3-dioxygenase-1 | Ocadlikova, Darina; Trabanelli, Sara; Salvestrini, Valentina; Ciciarello, Marilena; Evangelisti, ...Cecilia; Lecciso, MARIANGELA STEFANIA; Sabattini, Elena; Righi, Simona; Piccioli, Milena; Pileri, Stefano; Lemoli, ROBERTO MASSIMO; Curti, Antonio | 2015-01-01 | EXPERIMENTAL HEMATOLOGY | - | 1.01 Articolo in rivista | - |
| Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn's disease patients in a mouse model of colitis | Forte, Dorian; Ciciarello, Marilena; Valerii, MARIA CHIARA; DE FAZIO, Luigia; Cavazza, Elena; Gio...rdano, Rosaria; Parazzi, Valentina; Lazzari, Lorenza; Laureti, Silvio; Rizzello, Fernando; Cavo, Michele; Curti, Antonio; Lemoli, ROBERTO MASSIMO; Spisni, Enzo; Catani, Lucia | 2015-01-01 | STEM CELL RESEARCH & THERAPY | - | 1.01 Articolo in rivista | - |
| The Human Mesenchymal Stromal Cell-Derived Osteocyte Capacity to Modulate Dendritic Cell Functions Is Strictly Dependent on the Culture System | Trabanelli, Sara; La Manna, Federico; Romano, Marco; Salvestrini, Valentina; Cavo, Michele; Cicia...rello, Marilena; Lemoli, Roberto M; Curti, Antonio | 2015-01-01 | JOURNAL OF IMMUNOLOGY RESEARCH | - | 1.01 Articolo in rivista | - |
| Platelet lysate enhances the therapeutic activity of Adipose Derived Mesenchymal stromal cells isolated from Crohn disease patients in a novel Mouse model of Colitis | Dorian Forte; Marilena Ciciarello; Maria Chiara Valerii; Luigia De Fazio; Rosaria Giordano; Elisa... Montelatici; Silvio Laureti; Fernando Rizzello; Roberto Massimo Lemoli; Lucia Catani; Enzo Spisni | 2014-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| The role of the immunosuppressive microenvironment in acute myeloid leukemia development and treatment. | Isidori A; Salvestrini V; Ciciarello M; Loscocco F; Visani G; Parisi S; Lecciso M; Ocadlikova D; ...Rossi L; Gabucci E; Clissa C; Curti A. | 2014-01-01 | EXPERT REVIEW OF HEMATOLOGY | - | 1.01 Articolo in rivista | - |
| The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells. | Trabanelli S; Očadlíková D; Ciciarello M; Salvestrini V; Lecciso M; Jandus C; Metz R; Evangelisti... C; Laury-Kleintop L; Romero P; Prendergast GC; Curti A; Lemoli RM. | 2014-01-01 | JOURNAL OF IMMUNOLOGY | - | 1.01 Articolo in rivista | - |
| Extracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages. | Ciciarello M; Zini R; Rossi L; Salvestrini V; Ferrari D; Manfredini R; Lemoli RM. | 2013-01-01 | STEM CELLS AND DEVELOPMENT | - | 1.01 Articolo in rivista | - |