SANTUCCI, MARIA ALESSANDRA
SANTUCCI, MARIA ALESSANDRA
DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE (attivo dal 28/10/2011 al 31/12/2022)
14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia
2015 Mancini, Manuela; Leo, Elisa; Takemaru, Ken-Ichi; Campi, Virginia; Castagnetti, Fausto; Soverini, Simona; De Benedittis, Caterina; Rosti, Gianantonio; Cavo, Michele; Santucci, Maria Alessandra; Martinelli, Giovanni
14-3-3 ligand prevents nuclear import of c-ABL protein in chronic myeloid leukemia
2009 Mancini M; Veljkovic N; Corradi V; Zuffa E; Corrado P; Pagnotta E; Martinelli G; Barbieri E; Santucci MA.
9-HSA INDUCES APOPTOSIS AND INCREASES SENSITIVITY TO IMATINIB IN IMATINIB RESISTANT COLON CANCER CELLS
2006 Pagnotta E.; Calonghi N.; Parolin C.; Mangano C.; Nuccitelli A.; Boga C.; Santucci M.A.; Masotti L.
9-HSA INDUCES APOPTOSIS AND INCREASES SENSITIVITY TO IMATINIB IN IMATINIB RESISTANT COLON CANCER CELLS
2006 Pagnotta E.; Calonghi N.; Parolin C.; Mangano C.; Boga C.; Naldi M.; Santucci M.A.; Masotti L.
9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cells.
2004 N. CALONGHI; C. CAPPADONE; E. PAGNOTTA; G. FARRUGGIA; F. BUONTEMPO; C. BOGA; G.L. BRUSA; M.A. SANTUCCI; MASOTTI L.
A calpain-cleaved fragment of β-catenin promotes BCRABL1+ cell survival evoked by autophagy induction in response to imatinib
2014 Manuela Mancini;Elisa Leo;Virginia Campi;Fausto Castagnetti;Luca Zazzeroni;Gabriele Gugliotta;Maria Alessandra Santucci;Giovanni Martinelli
A new class of dual SRC/ABL kinase inhibitors for the treatment of imatinib-resistant chronic myeloid leukemias
2007 Corradi V.; Mancini M.; Corrado P.; Barbieri E.; Santucci M.A.; Schenone S.; Botta M.
Acetylation of FOXO3a transcription factor in response to imatinib of chronic myeloid leukemia
2009 Corrado P; Mancini M; Brusa G; Petta S; Martinelli G; Barbieri E; Santucci MA
Apoptotic death of Bcr-Abl-expressing myeloid progenitors in response to the m-Tor inhibitor RAD001 (Everolimus) is promoted by the nuclear import of c-Abl
2006 Mancini M.; Zuffa E.; Corrado P.; Brusa G.; Petta S.; Pagnotta E.; Santucci M.A.
BCR-ABL1-associated reduction of beta catenin antagonist Chibby1 in chronic myeloid leukemia.
2013 Leo E;Mancini M;Aluigi M;Luatti S;Castagnetti F;Testoni N;Soverini S;Santucci MA;Martinelli G
C6-Unsubstituted Pyrazolo[3,4-d]pyrimidines Are Dual Src/Abl Inhibitors Effective against Imatinib Mesylate Resistant Chronic Myeloid Leukemia Cell Lines.
2009 Santucci MA; Corradi V; Mancini M; Manetti F; Radi M; Schenone S; Botta M.
Chibby 1: A new component of β-catenin-signaling in chronic myeloid leukemia
2017 Mancini, Manuela; Soverini, Simona; Gugliotta, Gabriele; Santucci, MARIA ALESSANDRA; Rosti, Gianantonio; Cavo, Michele; Martinelli, Giovanni; Castagnetti, Fausto
Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1+ cells
2013 Manuela Mancini;Elisa Leo;Ken-Ichi Takemaru;Virginia Campi;Enrica Borsi;Fausto Castagnetti;Gabriele Gugliotta;Maria Alessandra Santucci;Giovanni Martinelli
CHK2 drives late G1/early S phase arrest of clonal myeloid progenitors expressing the p210 BCR-ABL tyrosine kinase in response to STI571
2004 MAZZACURATI L; PATTACINI L; BRUSA G; MANCINI M; BENVENUTI M; BARBIERI E; MARTINELLI G.; BACCARANI M; GREENBERGER JS; SANTUCCI MA
COVALENT MODIFICATIONS OF HISTONE H4 NH2-TERMINAL TAILS ASSOCIATED WITH P210 BCR-ABL TYROSINE KINASE
2004 Brusa G.; Parisi D.; Calonghi N.; Calabrò A.; Mancini M.; Zuffa E.; Arcangeli E.; Santucci M.A.
Cyclin-dependent kinase 2 (Cdk2) activity at the G1 to S boundary has a role in the resistance of Chronic Myeloid Leukemia (CML) haematopoietic progenitors to the tyrosine kinase inhibitor STI571 (Imatinib)
2004 M. Mancini; G. Brusa; A. Calabrò; N. Calonghi; E. Pagnotta; M. Alessandra Santucci; L. Masotti
Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia
2012 Manuela Mancini;Nevena Veljkovic;Elisa Leo;Michela Aluigi;Enrica Borsi;Chiara Galloni;Ilaria Iacobucci;Enza Barbieri;Maria Alessandra Santucci
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.
2008 Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schenone S; Botta M.
DNA methyltransferase 1 drives transcriptional down-modulation of β catenin antagonist Chibby1 associated with the BCR-ABL1 gene of chronic myeloid leukemia.
2015 Leo, E; Mancini, M; Castagnetti, F; Gugliotta, G; Santucci, Ma; Martinelli, G.
Endoplasmic reticulum stress initiates apoptotic death induced by STI571 inhibition of p210 bcr-abl tyrosine kinase.
2004 PATTACINI L; MANCINI M; MAZZACURATI L; BRUSA G; BENVENUTI M; MARTINELLI G.; BACCARANI M; SANTUCCI MA.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| 14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia | Mancini, Manuela; Leo, Elisa; Takemaru, Ken-Ichi; Campi, Virginia; Castagnetti, Fausto; Soverini,... Simona; De Benedittis, Caterina; Rosti, Gianantonio; Cavo, Michele; Santucci, Maria Alessandra; Martinelli, Giovanni | 2015-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | Mancini_PONE_2015.pdf; pone.0131074.s001.pdf; pone.0131074.s002.pdf; pone.0131074.s003.pdf; pone.0131074.s004.pdf; pone.0131074.s004.pdf |
| 14-3-3 ligand prevents nuclear import of c-ABL protein in chronic myeloid leukemia | Mancini M; Veljkovic N; Corradi V; Zuffa E; Corrado P; Pagnotta E; Martinelli G; Barbieri E; Sant...ucci MA. | 2009-01-01 | TRAFFIC | - | 1.01 Articolo in rivista | - |
| 9-HSA INDUCES APOPTOSIS AND INCREASES SENSITIVITY TO IMATINIB IN IMATINIB RESISTANT COLON CANCER CELLS | Pagnotta E.; Calonghi N.; Parolin C.; Mangano C.; Nuccitelli A.; Boga C.; Santucci M.A.; Masotti L. | 2006-01-01 | - | fondazione per le biotecnologie | 4.02 Riassunto (Abstract) | - |
| 9-HSA INDUCES APOPTOSIS AND INCREASES SENSITIVITY TO IMATINIB IN IMATINIB RESISTANT COLON CANCER CELLS | Pagnotta E.; Calonghi N.; Parolin C.; Mangano C.; Boga C.; Naldi M.; Santucci M.A.; Masotti L. | 2006-01-01 | ITALIAN JOURNAL OF BIOCHEMISTRY | - | 4.02 Riassunto (Abstract) | - |
| 9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cells. | N. CALONGHI; C. CAPPADONE; E. PAGNOTTA; G. FARRUGGIA; F. BUONTEMPO; C. BOGA; G.L. BRUSA; M.A. SAN...TUCCI; MASOTTI L. | 2004-01-01 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - | 1.01 Articolo in rivista | - |
| A calpain-cleaved fragment of β-catenin promotes BCRABL1+ cell survival evoked by autophagy induction in response to imatinib | Manuela Mancini;Elisa Leo;Virginia Campi;Fausto Castagnetti;Luca Zazzeroni;Gabriele Gugliotta;Mar...ia Alessandra Santucci;Giovanni Martinelli | 2014-01-01 | CELLULAR SIGNALLING | - | 1.01 Articolo in rivista | - |
| A new class of dual SRC/ABL kinase inhibitors for the treatment of imatinib-resistant chronic myeloid leukemias | Corradi V.; Mancini M.; Corrado P.; Barbieri E.; Santucci M.A.; Schenone S.; Botta M. | 2007-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Acetylation of FOXO3a transcription factor in response to imatinib of chronic myeloid leukemia | Corrado P; Mancini M; Brusa G; Petta S; Martinelli G; Barbieri E; Santucci MA | 2009-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Apoptotic death of Bcr-Abl-expressing myeloid progenitors in response to the m-Tor inhibitor RAD001 (Everolimus) is promoted by the nuclear import of c-Abl | Mancini M.; Zuffa E.; Corrado P.; Brusa G.; Petta S.; Pagnotta E.; Santucci M.A. | 2006-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| BCR-ABL1-associated reduction of beta catenin antagonist Chibby1 in chronic myeloid leukemia. | Leo E;Mancini M;Aluigi M;Luatti S;Castagnetti F;Testoni N;Soverini S;Santucci MA;Martinelli G | 2013-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | Leo et al_PONE2013.pdf |
| C6-Unsubstituted Pyrazolo[3,4-d]pyrimidines Are Dual Src/Abl Inhibitors Effective against Imatinib Mesylate Resistant Chronic Myeloid Leukemia Cell Lines. | Santucci MA; Corradi V; Mancini M; Manetti F; Radi M; Schenone S; Botta M. | 2009-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Chibby 1: A new component of β-catenin-signaling in chronic myeloid leukemia | Mancini, Manuela; Soverini, Simona; Gugliotta, Gabriele; Santucci, MARIA ALESSANDRA; Rosti, Giana...ntonio; Cavo, Michele; Martinelli, Giovanni; Castagnetti, Fausto | 2017-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1+ cells | Manuela Mancini;Elisa Leo;Ken-Ichi Takemaru;Virginia Campi;Enrica Borsi;Fausto Castagnetti;Gabrie...le Gugliotta;Maria Alessandra Santucci;Giovanni Martinelli | 2013-01-01 | CELLULAR SIGNALLING | - | 1.01 Articolo in rivista | - |
| CHK2 drives late G1/early S phase arrest of clonal myeloid progenitors expressing the p210 BCR-ABL tyrosine kinase in response to STI571 | MAZZACURATI L; PATTACINI L; BRUSA G; MANCINI M; BENVENUTI M; BARBIERI E; MARTINELLI G.; BACCARANI... M; GREENBERGER JS; SANTUCCI MA | 2004-01-01 | HEMATOLOGY JOURNAL | - | 1.01 Articolo in rivista | - |
| COVALENT MODIFICATIONS OF HISTONE H4 NH2-TERMINAL TAILS ASSOCIATED WITH P210 BCR-ABL TYROSINE KINASE | Brusa G.; Parisi D.; Calonghi N.; Calabrò A.; Mancini M.; Zuffa E.; Arcangeli E.; Santucci M.A. | 2004-01-01 | - | Mario Cazzola | 4.01 Contributo in Atti di convegno | - |
| Cyclin-dependent kinase 2 (Cdk2) activity at the G1 to S boundary has a role in the resistance of Chronic Myeloid Leukemia (CML) haematopoietic progenitors to the tyrosine kinase inhibitor STI571 (Imatinib) | M. Mancini; G. Brusa; A. Calabrò; N. Calonghi; E. Pagnotta; M. Alessandra Santucci; L. Masotti | 2004-01-01 | - | Graphital | 4.01 Contributo in Atti di convegno | - |
| Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia | Manuela Mancini;Nevena Veljkovic;Elisa Leo;Michela Aluigi;Enrica Borsi;Chiara Galloni;Ilaria Iaco...bucci;Enza Barbieri;Maria Alessandra Santucci | 2012-01-01 | JOURNAL OF CELLULAR BIOCHEMISTRY | - | 1.01 Articolo in rivista | - |
| Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. | Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schen...one S; Botta M. | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| DNA methyltransferase 1 drives transcriptional down-modulation of β catenin antagonist Chibby1 associated with the BCR-ABL1 gene of chronic myeloid leukemia. | Leo, E; Mancini, M; Castagnetti, F; Gugliotta, G; Santucci, Ma; Martinelli, G. | 2015-01-01 | JOURNAL OF CELLULAR BIOCHEMISTRY | - | 1.01 Articolo in rivista | - |
| Endoplasmic reticulum stress initiates apoptotic death induced by STI571 inhibition of p210 bcr-abl tyrosine kinase. | PATTACINI L; MANCINI M; MAZZACURATI L; BRUSA G; BENVENUTI M; MARTINELLI G.; BACCARANI M; SANTUCCI... MA. | 2004-01-01 | LEUKEMIA RESEARCH | - | 1.01 Articolo in rivista | - |