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FUCHS, CLAUDIA

FUCHS, CLAUDIA  

DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE  

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Titolo Autore(i) Anno Periodico Editore Tipo File
Treatment with FRAX486 rescues neurobehavioral and metabolic alterations in a female mouse model of CDKL5 deficiency disorder Fuchs, Claudia; Cosentino, Livia; Urbinati, Chiara; Talamo, Maria Cristina; Medici, Giorgio; Quat...trini, Maria Cristina; Mottolese, Nicola; Pietraforte, Donatella; Fuso, Andrea; Ciani, Elisabetta; De Filippis, Bianca 2022-01-01 CNS NEUROSCIENCE & THERAPEUTICS - 1.01 Articolo in rivista CNS-28-1718.pdf; file supplementare.zip
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali..., Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani 2021-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista Gennaccaro et al 2021GABA.pdf; Supplementary data.docx
Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvan...i G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E. 2021-01-01 AGING AND DISEASE - 1.01 Articolo in rivista Gennaccaro et al 2021Age.pdf
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari..., Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania 2021-01-01 JOURNAL OF NEUROINFLAMMATION - 1.01 Articolo in rivista Galvani et al 2021.pdf
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Gius...eppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta 2021-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista Loi et al 2021.pdf; ijms-1212824-supplementary.pdf
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali,
Elisa ...Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani 		2020-01-01 - - 4.03 Poster -
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E. 2020-01-01 MOLECULAR NEUROBIOLOGY - 1.01 Articolo in rivista -
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O....; Rimondini R.; Ciani E. 2020-01-01 NEUROPHARMACOLOGY - 1.01 Articolo in rivista -
The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo Trovo L.; Fuchs C.; De Rosa R.; Barbiero I.; Tramarin M.; Ciani E.; Rusconi L.; Kilstrup-Nielsen C. 2020-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista 1-s2.0-S0969996120300668-main.pdf
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019) Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E. 2019-01-01 BRAIN PATHOLOGY - 1.01 Articolo in rivista -
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rim...ondini R.; Aicardi G.; Ciani E. 2019-01-01 FRONTIERS IN CELLULAR NEUROSCIENCE - 1.01 Articolo in rivista fncel-13-00169.pdf
Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder Lupori L.; Sagona G.; Fuchs C.; Mazziotti R.; Stefanov A.; Putignano E.; Napoli D.; Strettoi E.; ...Ciani E.; Pizzorusso T. 2019-01-01 HUMAN MOLECULAR GENETICS - 1.01 Articolo in rivista ddz102.pdf; supplementary_material_ddz102.pdf
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchin...a; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta* 2018-01-01 HUMAN MOLECULAR GENETICS - 1.01 Articolo in rivista trazzi2018 .pdf
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martir...e, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta* 2018-01-01 NEURAL PLASTICITY - 1.01 Articolo in rivista 9726950(1).pdf; Supplementary Materials.zip
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Mar...tire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta 2018-01-01 NEURAL PLASTICITY - 1.01 Articolo in rivista -
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, E...lisabetta* 2018-01-01 EUROPEAN JOURNAL OF NEUROSCIENCE - 1.01 Articolo in rivista -
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder Trazzi, Stefania; Fuchs, Claudia; Viggiano, ROCCHINA ASSUNTA; DE FRANCESCHI, Marianna; Valli, Ema...nuele; Jedynak, Paulina; Hansen, Finn K; Perini, Giovanni; RIMONDINI GIORGINI, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta 2016-01-01 HUMAN MOLECULAR GENETICS - 1.01 Articolo in rivista -
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder Fuchs, C.; Rimondini, R.; Viggiano, R.; Trazzi, S.; De Franceschi, M.; Bartesaghi, R.; Ciani, E. 2015-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista -
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome. Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E 2014-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista -
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. Fuchs C;Trazzi S;Torricella R;Viggiano R;De Franceschi M;Amendola E;Gross C;Calzà L;Bartesaghi R;...Ciani E 2014-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista -