DI FEDERICO, ALESSANDRO
DI FEDERICO, ALESSANDRO
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Assegnisti
Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors
2024 Pecci F.; Nakazawa S.; Ricciuti B.; Harada G.; Lee J.K.; Alessi J.V.; Barrichello A.; Vaz V.R.; Lamberti G.; Di Federico A.; Gandhi M.M.; Gazgalis D.; Feng W.W.; Jiang J.; Baldacci S.; Locquet M.-A.; Gottlieb F.H.; Chen M.F.; Lee E.; Haradon D.; Smokovich A.; Voligny E.; Nguyen T.; Goel V.K.; Zimmerman Z.; Atwal S.; Wang X.; Bahcall M.; Heist R.S.; Iqbal S.; Gandhi N.; Elliott A.; Vanderwalde A.M.; Ma P.C.; Halmos B.; Liu S.V.; Che J.; Schrock A.B.; Drilon A.; Janne P.A.; Awad M.M.
Development and validation of a new tool to estimate early mortality in patients with advanced cancer treated with immunotherapy
2024 De Giglio, Andrea; Leonetti, Alessandro; Comito, Francesca; Filippini, Daria Maria; Mollica, Veronica; Rihawi, Karim; Peroni, Marianna; Mazzaschi, Giulia; Ricciotti, Ilaria; Carosi, Francesca; Marchetti, Andrea; Rosellini, Matteo; Gagliano, Ambrogio; Favorito, Valentina; Nobili, Elisabetta; Gelsomino, Francesco; Melotti, Barbara; Marchese, Paola Valeria; Sperandi, Francesca; Di Federico, Alessandro; Buti, Sebastiano; Perrone, Fabiana; Massari, Francesco; Pantaleo, Maria Abbondanza; Tiseo, Marcello; Ardizzoni, Andrea
Early monitoring of plasma KRAS G12C with digital PCR predicts antitumor response to immunotherapy or sotorasib in advanced NSCLC: A brief report
2024 De Giglio, Andrea; Zacchini, Federico; Venturi, Giulia; Di Federico, Alessandro; Parisi, Claudia; Dall'Olio, Filippo Gustavo; Ricciotti, Ilaria; Favorito, Valentina; Gagliano, Ambrogio; De Biase, Dario; Maloberti, Thais; Altimari, Annalisa; Gruppioni, Elisa; Tallini, Giovanni; Melotti, Barbara; Sperandi, Francesca; Gelsomino, Francesco; Montanaro, Lorenzo; Ardizzoni, Andrea
Effective retreatment with osimertinib in CNS-relapsed epidermal growth factor receptor-mutant non-small cell lung cancer patient following resection and adjuvant osimertinib
2024 Di Federico A.; De Giglio A.; Sperandi F.; Melotti B.; Ardizzoni A.; Gelsomino F.
From Development to Place in Therapy of Lorlatinib for the Treatment of ALK and ROS1 Rearranged Non-Small Cell Lung Cancer (NSCLC)
2024 Fabbri L.; Di Federico A.; Astore M.; Marchiori V.; Rejtano A.; Seminerio R.; Gelsomino F.; De Giglio A.
Genomic and Immunophenotypic Landscape of Acquired Resistance to PD-(L)1 Blockade in Non-Small-Cell Lung Cancer
2024 Ricciuti B.; Lamberti G.; Puchala S.R.; Mahadevan N.R.; Lin J.-R.; Alessi J.V.; Chowdhury A.; Li Y.Y.; Wang X.; Spurr L.; Pecci F.; Di Federico A.; Venkatraman D.; Barrichello A.P.; Gandhi M.; Vaz V.R.; Pangilinan A.J.; Haradon D.; Lee E.; Gupta H.; Pfaff K.L.; Welsh E.L.; Nishino M.; Cherniack A.D.; Johnson B.E.; Weirather J.L.; Dryg I.D.; Rodig S.J.; Sholl L.M.; Sorger P.; Santagata S.; Umeton R.; Awad M.M.
Histopathological Evidence for a Non-Inflammatory Mechanism in Osimertinib-Induced Myopathy: A Case Report
2024 Rossi S.; Costa R.; di Federico A.; Lo Bianco F.; D'Angelo R.; Asioli G.M.; De Giglio A.; Sperandi F.; Guarino M.; Rinaldi R.; Ardizzoni A.; Cenacchi G.; Gelsomino F.
Navigating challenges in EGFR exon 20 insertions: The PAPILLON trial unravels the promise of amivantamab-chemotherapy
2024 De Giglio A.; Di Federico A.; Gariazzo E.; Metro G.
Non-small cell lung cancer: an update on emerging EGFR-targeted therapies
2024 Favorito V.; Ricciotti I.; De Giglio A.; Fabbri L.; Seminerio R.; Di Federico A.; Gariazzo E.; Costabile S.; Metro G.
Tumor mutational burden for the prediction of PD-(L)1 blockade efficacy in cancer: challenges and opportunities
2024 Wang X.; Lamberti G.; Di Federico A.; Alessi J.; Ferrara R.; Sholl M.L.; Awad M.M.; Vokes N.; Ricciuti B.
Bone-specific response according to MDA criteria predicts immunotherapy efficacy among advanced non-small cell lung cancer (NSCLC) patients
2023 De Giglio A.; Deiana C.; Di Federico A.
Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
2023 Thummalapalli R.; Ricciuti B.; Bandlamudi C.; Muldoon D.; Rizvi H.; Elkrief A.; Luo J.; Alessi J.V.; Pecci F.; Lamberti G.; Di Federico A.; Hong L.; Zhang J.; Heymach J.V.; Gibbons D.L.; Plodkowski A.J.; Ravichandran V.; Donoghue M.T.A.; Vanderbilt C.; Ladanyi M.; Rudin C.M.; Kris M.G.; Riely G.J.; Chaft J.E.; Hellmann M.D.; Vokes N.I.; Awad M.M.; Schoenfeld A.J.
Clinical Utility and Application of Liquid Biopsy Genotyping in Lung Cancer: A Comprehensive Review
2023 Nigro M.C.; Marchese P.V.; Deiana C.; Casadio C.; Galvani L.; Di Federico A.; De Giglio A.
Clinicopathologic and Genomic Factors Impacting Efficacy of First-Line Chemoimmunotherapy in Advanced NSCLC
2023 Alessi J.V.; Elkrief A.; Ricciuti B.; Wang X.; Cortellini A.; Vaz V.R.; Lamberti G.; Frias R.L.; Venkatraman D.; Fulgenzi C.A.M.; Pecci F.; Recondo G.; Di Federico A.; Barrichello A.; Park H.; Nishino M.; Hambelton G.M.; Egger J.V.; Ladanyi M.; Digumarthy S.; Johnson B.E.; Christiani D.C.; Lin X.; Gainor J.F.; Lin J.J.; Pinato D.J.; Schoenfeld A.J.; Awad M.M.
Clonal KEAP1 mutations with loss of heterozygosity share reduced immunotherapy efficacy and low immune cell infiltration in lung adenocarcinoma
2023 Scalera S.; Ricciuti B.; Mazzotta M.; Calonaci N.; Alessi J.V.; Cipriani L.; Bon G.; Messina B.; Lamberti G.; Di Federico A.; Pecci F.; Milite S.; Krasniqi E.; Barba M.; Vici P.; Vecchione A.; De Nicola F.; Ciuffreda L.; Goeman F.; Fanciulli M.; Buglioni S.; Pescarmona E.; Sharma B.; Felt K.D.; Lindsay J.; Rodig S.J.; De Maria R.; Caravagna G.; Cappuzzo F.; Ciliberto G.; Awad M.M.; Maugeri-Sacca M.
Efficacy of PD-(L)1 blockade monotherapy compared with PD-(L)1 blockade plus chemotherapy in first-line PD-L1-positive advanced lung adenocarcinomas: A cohort study
2023 Elkrief A.; Alessi J.M.V.; Ricciuti B.; Brown S.; Rizvi H.; Preeshagul I.R.; Wang X.; Pecci F.; Di Federico A.; Lamberti G.; Egger J.V.; Chaft J.E.; Rudin C.M.; Riely G.J.; Kris M.G.; Ladanyi M.; Chen Y.; Hellmann M.D.; Shen R.; Awad M.M.; Schoenfeld A.J.
First-Generation Epidermal Growth Factor Receptor Inhibitors Plus Antiangiogenic Drugs Versus Third-Generation Epidermal Growth Factor Receptor Inhibitors in Advanced Non-Small-Cell Lung Cancer: A Meta-Analysis
2023 Mosca, Mirta; Conci, Nicole; Di Federico, Alessandro; Tateo, Valentina; Favorito, Valentina; Zappi, Arianna; Gelsomino, Francesco; De Giglio, Andrea
Impact of Aneuploidy and Chromosome 9p Loss on Tumor Immune Microenvironment and Immune Checkpoint Inhibitor Efficacy in NSCLC
2023 Alessi J.V.; Wang X.; Elkrief A.; Ricciuti B.; Li Y.Y.; Gupta H.; Spurr L.F.; Rizvi H.; Luo J.; Pecci F.; Lamberti G.; Recondo G.; Venkatraman D.; Di Federico A.; Gandhi M.M.; Vaz V.R.; Nishino M.; Sholl L.M.; Cherniack A.D.; Ladanyi M.; Price A.; Richards A.L.; Donoghue M.; Lindsay J.; Sharma B.; Turner M.M.; Pfaff K.L.; Felt K.D.; Rodig S.J.; Lin X.; Meyerson M.L.; Johnson B.E.; Christiani D.C.; Schoenfeld A.J.; Awad M.M.
Impact of TMB/PD-L1 expression and pneumonitis on chemoradiation and durvalumab response in stage III NSCLC
2023 Alessi J.V.; Ricciuti B.; Wang X.; Pecci F.; Di Federico A.; Lamberti G.; Elkrief A.; Rodig S.J.; Lebow E.S.; Eicholz J.E.; Thor M.; Rimner A.; Schoenfeld A.J.; Chaft J.E.; Johnson B.E.; Gomez D.R.; Awad M.M.; Shaverdian N.
Neutrophil-to-Lymphocyte Ratio (NLR) in NSCLC, Gastrointestinal, and Other Solid Tumors: Immunotherapy and Beyond
2023 Mosca M.; Nigro M.C.; Pagani R.; De Giglio A.; Di Federico A.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors | Pecci F.; Nakazawa S.; Ricciuti B.; Harada G.; Lee J.K.; Alessi J.V.; Barrichello A.; Vaz V.R.; L...amberti G.; Di Federico A.; Gandhi M.M.; Gazgalis D.; Feng W.W.; Jiang J.; Baldacci S.; Locquet M.-A.; Gottlieb F.H.; Chen M.F.; Lee E.; Haradon D.; Smokovich A.; Voligny E.; Nguyen T.; Goel V.K.; Zimmerman Z.; Atwal S.; Wang X.; Bahcall M.; Heist R.S.; Iqbal S.; Gandhi N.; Elliott A.; Vanderwalde A.M.; Ma P.C.; Halmos B.; Liu S.V.; Che J.; Schrock A.B.; Drilon A.; Janne P.A.; Awad M.M. | 2024-01-01 | CANCER DISCOVERY | - | 1.01 Articolo in rivista | cd-23-1217.pdf; 7384706.zip |
| Development and validation of a new tool to estimate early mortality in patients with advanced cancer treated with immunotherapy | De Giglio, Andrea; Leonetti, Alessandro; Comito, Francesca; Filippini, Daria Maria; Mollica, Vero...nica; Rihawi, Karim; Peroni, Marianna; Mazzaschi, Giulia; Ricciotti, Ilaria; Carosi, Francesca; Marchetti, Andrea; Rosellini, Matteo; Gagliano, Ambrogio; Favorito, Valentina; Nobili, Elisabetta; Gelsomino, Francesco; Melotti, Barbara; Marchese, Paola Valeria; Sperandi, Francesca; Di Federico, Alessandro; Buti, Sebastiano; Perrone, Fabiana; Massari, Francesco; Pantaleo, Maria Abbondanza; Tiseo, Marcello; Ardizzoni, Andrea | 2024-01-01 | CANCER IMMUNOLOGY, IMMUNOTHERAPY | - | 1.01 Articolo in rivista | Cancer Immunol Immunot 2024 [Early Mortality DeGiglio].pdf; 262_2024_3836_MOESM1_ESM.docx |
| Early monitoring of plasma KRAS G12C with digital PCR predicts antitumor response to immunotherapy or sotorasib in advanced NSCLC: A brief report | De Giglio, Andrea; Zacchini, Federico; Venturi, Giulia; Di Federico, Alessandro; Parisi, Claudia;... Dall'Olio, Filippo Gustavo; Ricciotti, Ilaria; Favorito, Valentina; Gagliano, Ambrogio; De Biase, Dario; Maloberti, Thais; Altimari, Annalisa; Gruppioni, Elisa; Tallini, Giovanni; Melotti, Barbara; Sperandi, Francesca; Gelsomino, Francesco; Montanaro, Lorenzo; Ardizzoni, Andrea | 2024-01-01 | THE JOURNAL OF LIQUID BIOPSY | - | 1.01 Articolo in rivista | - |
| Effective retreatment with osimertinib in CNS-relapsed epidermal growth factor receptor-mutant non-small cell lung cancer patient following resection and adjuvant osimertinib | Di Federico A.; De Giglio A.; Sperandi F.; Melotti B.; Ardizzoni A.; Gelsomino F. | 2024-01-01 | ANTI-CANCER DRUGS | - | 1.01 Articolo in rivista | - |
| From Development to Place in Therapy of Lorlatinib for the Treatment of ALK and ROS1 Rearranged Non-Small Cell Lung Cancer (NSCLC) | Fabbri L.; Di Federico A.; Astore M.; Marchiori V.; Rejtano A.; Seminerio R.; Gelsomino F.; De Gi...glio A. | 2024-01-01 | DIAGNOSTICS | - | 1.01 Articolo in rivista | diagnostics-14-00048-v2.pdf |
| Genomic and Immunophenotypic Landscape of Acquired Resistance to PD-(L)1 Blockade in Non-Small-Cell Lung Cancer | Ricciuti B.; Lamberti G.; Puchala S.R.; Mahadevan N.R.; Lin J.-R.; Alessi J.V.; Chowdhury A.; Li ...Y.Y.; Wang X.; Spurr L.; Pecci F.; Di Federico A.; Venkatraman D.; Barrichello A.P.; Gandhi M.; Vaz V.R.; Pangilinan A.J.; Haradon D.; Lee E.; Gupta H.; Pfaff K.L.; Welsh E.L.; Nishino M.; Cherniack A.D.; Johnson B.E.; Weirather J.L.; Dryg I.D.; Rodig S.J.; Sholl L.M.; Sorger P.; Santagata S.; Umeton R.; Awad M.M. | 2024-01-01 | JOURNAL OF CLINICAL ONCOLOGY | - | 1.01 Articolo in rivista | jco-42-1311.pdf |
| Histopathological Evidence for a Non-Inflammatory Mechanism in Osimertinib-Induced Myopathy: A Case Report | Rossi S.; Costa R.; di Federico A.; Lo Bianco F.; D'Angelo R.; Asioli G.M.; De Giglio A.; Sperand...i F.; Guarino M.; Rinaldi R.; Ardizzoni A.; Cenacchi G.; Gelsomino F. | 2024-01-01 | JOURNAL OF THORACIC ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Navigating challenges in EGFR exon 20 insertions: The PAPILLON trial unravels the promise of amivantamab-chemotherapy | De Giglio A.; Di Federico A.; Gariazzo E.; Metro G. | 2024-01-01 | MED | - | 1.01 Articolo in rivista | - |
| Non-small cell lung cancer: an update on emerging EGFR-targeted therapies | Favorito V.; Ricciotti I.; De Giglio A.; Fabbri L.; Seminerio R.; Di Federico A.; Gariazzo E.; Co...stabile S.; Metro G. | 2024-01-01 | EXPERT OPINION ON EMERGING DRUGS | - | 1.01 Articolo in rivista | - |
| Tumor mutational burden for the prediction of PD-(L)1 blockade efficacy in cancer: challenges and opportunities | Wang X.; Lamberti G.; Di Federico A.; Alessi J.; Ferrara R.; Sholl M.L.; Awad M.M.; Vokes N.; Ric...ciuti B. | 2024-01-01 | ANNALS OF ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Bone-specific response according to MDA criteria predicts immunotherapy efficacy among advanced non-small cell lung cancer (NSCLC) patients | De Giglio A.; Deiana C.; Di Federico A. | 2023-01-01 | JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY | - | 1.01 Articolo in rivista | De_Giglio_2023.pdf; 432_2022_4120_MOESM1_ESM.png |
| Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer | Thummalapalli R.; Ricciuti B.; Bandlamudi C.; Muldoon D.; Rizvi H.; Elkrief A.; Luo J.; Alessi J....V.; Pecci F.; Lamberti G.; Di Federico A.; Hong L.; Zhang J.; Heymach J.V.; Gibbons D.L.; Plodkowski A.J.; Ravichandran V.; Donoghue M.T.A.; Vanderbilt C.; Ladanyi M.; Rudin C.M.; Kris M.G.; Riely G.J.; Chaft J.E.; Hellmann M.D.; Vokes N.I.; Awad M.M.; Schoenfeld A.J. | 2023-01-01 | CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | Thummalapalli_2021.pdf; 6908245.zip |
| Clinical Utility and Application of Liquid Biopsy Genotyping in Lung Cancer: A Comprehensive Review | Nigro M.C.; Marchese P.V.; Deiana C.; Casadio C.; Galvani L.; Di Federico A.; De Giglio A. | 2023-01-01 | LUNG CANCER: TARGETS AND THERAPY | - | 1.01 Articolo in rivista | - |
| Clinicopathologic and Genomic Factors Impacting Efficacy of First-Line Chemoimmunotherapy in Advanced NSCLC | Alessi J.V.; Elkrief A.; Ricciuti B.; Wang X.; Cortellini A.; Vaz V.R.; Lamberti G.; Frias R.L.; ...Venkatraman D.; Fulgenzi C.A.M.; Pecci F.; Recondo G.; Di Federico A.; Barrichello A.; Park H.; Nishino M.; Hambelton G.M.; Egger J.V.; Ladanyi M.; Digumarthy S.; Johnson B.E.; Christiani D.C.; Lin X.; Gainor J.F.; Lin J.J.; Pinato D.J.; Schoenfeld A.J.; Awad M.M. | 2023-01-01 | JOURNAL OF THORACIC ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Clonal KEAP1 mutations with loss of heterozygosity share reduced immunotherapy efficacy and low immune cell infiltration in lung adenocarcinoma | Scalera S.; Ricciuti B.; Mazzotta M.; Calonaci N.; Alessi J.V.; Cipriani L.; Bon G.; Messina B.; ...Lamberti G.; Di Federico A.; Pecci F.; Milite S.; Krasniqi E.; Barba M.; Vici P.; Vecchione A.; De Nicola F.; Ciuffreda L.; Goeman F.; Fanciulli M.; Buglioni S.; Pescarmona E.; Sharma B.; Felt K.D.; Lindsay J.; Rodig S.J.; De Maria R.; Caravagna G.; Cappuzzo F.; Ciliberto G.; Awad M.M.; Maugeri-Sacca M. | 2023-01-01 | ANNALS OF ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Efficacy of PD-(L)1 blockade monotherapy compared with PD-(L)1 blockade plus chemotherapy in first-line PD-L1-positive advanced lung adenocarcinomas: A cohort study | Elkrief A.; Alessi J.M.V.; Ricciuti B.; Brown S.; Rizvi H.; Preeshagul I.R.; Wang X.; Pecci F.; D...i Federico A.; Lamberti G.; Egger J.V.; Chaft J.E.; Rudin C.M.; Riely G.J.; Kris M.G.; Ladanyi M.; Chen Y.; Hellmann M.D.; Shen R.; Awad M.M.; Schoenfeld A.J. | 2023-01-01 | JOURNAL FOR IMMUNOTHERAPY OF CANCER | - | 1.01 Articolo in rivista | Elkrief_2023+suppl.pdf |
| First-Generation Epidermal Growth Factor Receptor Inhibitors Plus Antiangiogenic Drugs Versus Third-Generation Epidermal Growth Factor Receptor Inhibitors in Advanced Non-Small-Cell Lung Cancer: A Meta-Analysis | Mosca, Mirta; Conci, Nicole; Di Federico, Alessandro; Tateo, Valentina; Favorito, Valentina; Zapp...i, Arianna; Gelsomino, Francesco; De Giglio, Andrea | 2023-01-01 | JCO PRECISION ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Impact of Aneuploidy and Chromosome 9p Loss on Tumor Immune Microenvironment and Immune Checkpoint Inhibitor Efficacy in NSCLC | Alessi J.V.; Wang X.; Elkrief A.; Ricciuti B.; Li Y.Y.; Gupta H.; Spurr L.F.; Rizvi H.; Luo J.; P...ecci F.; Lamberti G.; Recondo G.; Venkatraman D.; Di Federico A.; Gandhi M.M.; Vaz V.R.; Nishino M.; Sholl L.M.; Cherniack A.D.; Ladanyi M.; Price A.; Richards A.L.; Donoghue M.; Lindsay J.; Sharma B.; Turner M.M.; Pfaff K.L.; Felt K.D.; Rodig S.J.; Lin X.; Meyerson M.L.; Johnson B.E.; Christiani D.C.; Schoenfeld A.J.; Awad M.M. | 2023-01-01 | JOURNAL OF THORACIC ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Impact of TMB/PD-L1 expression and pneumonitis on chemoradiation and durvalumab response in stage III NSCLC | Alessi J.V.; Ricciuti B.; Wang X.; Pecci F.; Di Federico A.; Lamberti G.; Elkrief A.; Rodig S.J.;... Lebow E.S.; Eicholz J.E.; Thor M.; Rimner A.; Schoenfeld A.J.; Chaft J.E.; Johnson B.E.; Gomez D.R.; Awad M.M.; Shaverdian N. | 2023-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | Alessi_2023.pdf; 41467_2023_39874_MOESM1_ESM.pdf |
| Neutrophil-to-Lymphocyte Ratio (NLR) in NSCLC, Gastrointestinal, and Other Solid Tumors: Immunotherapy and Beyond | Mosca M.; Nigro M.C.; Pagani R.; De Giglio A.; Di Federico A. | 2023-01-01 | BIOMOLECULES | - | 1.01 Articolo in rivista | biomolecules-13-01803.pdf |