GHERARDI, SAMUELE
GHERARDI, SAMUELE
CIRI SCIENZE DELLA VITA E TECNOLOGIE PER LA SALUTE
Transcriptional and epigenetic analyses of the DMD locus reveal novel cisâacting DNA elements that govern muscle dystrophin expression
2017 Gherardi, Samuele; Bovolenta, Matteo; Passarelli, Chiara; Falzarano, Maria Sofia; Pigini, Paolo; Scotton, Chiara; Neri, Marcella; Armaroli, Annarita; Osman, Hana; Selvatici, Rita; Gualandi, Francesca; Recchia, Alessandra; Mora, Marina; Bernasconi, Pia; Maggi, Lorenzo; Morandi, Lucia; Ferlini, Alessandra; Perini, Giovanni
MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma
2015 Lau, Diana T; Flemming, Claudia L; Gherardi, Samuele; Perini, Giovanni; Oberthuer, André; Fischer, Matthias; Juraeva, Dilafruz; Brors, Benedikt; Xue, Chengyuan; Norris, Murray D; Marshall, Glenn M; Haber, Michelle; Fletcher, Jamie I; Ashton, Lesley J
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma
2015 Evans, Laura; Chen, Lindi; Milazzo, Giorgio; Gherardi, Samuele; Perini, Giovanni; Willmore, Elaine; Newell, David R.; Tweddle, Deborah A.
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma
2015 Sun, Yuting; Bell, Jessica L; Carter, Daniel; Gherardi, Samuele; Poulos, Rebecca C; Milazzo, Giorgio; Wong, Jason W H; Al-Awar, Rima; Tee, Andrew E; Liu, Pei Y; Liu, Bing; Atmadibrata, Bernard; Wong, Matthew; Trahair, Toby; Zhao, Quan; Shohet, Jason M; Haupt, Ygal; Schulte, Johannes H; Brown, Peter J; Arrowsmith, Cheryl H; Vedadi, Masoud; Mackenzie, Karen L; Hüttelmaier, Stefan; Perini, Giovanni; Marshall, Glenn M; Braithwaite, Antony; Liu, Tao
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin.
2013 Gherardi S; Valli E; Erriquez D; Perini G.
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications.
2013 Corvetta D; Chayka O; Gherardi S; D'Acunto CW; Cantilena S; Valli E; Piotrowska I; Perini G; Sala A.
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma
2012 Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R. Wagenaar; Michael R. Green
N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma
2012 Fletcher J.I.; Gherardi S.; Murray J.; Burkhart C.A.; Russell A.; Valli E.; Smith J.; Oberthuer A.; Ashton L.J.; London W.B.; Marshall G.M.; Norris M.D.; Perini G.; Haber M.
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms.
2012 Bovolenta M.; Erriquez D.; Valli E.; Brioschi S.; Scotton C.; Neri M.; Falzarano M.S.; Gherardi S.; Fabris M.; Rimessi P.; Gualandi F.; Perini G.; Ferlini A.
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF
2011 Iraci N.; Diolaiti D.; Papa A.; Porro A.; Valli E.; Gherardi S.; Herold S.; Eilers M.; Bernardoni R.; Della Valle G.; Perini G.
ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux
2011 Henderson M.; Porro A.; Munoz M.; Iraci N.; Xue C.; Murray J.; Flemming C.; Smith J.; Fletcher J.; Gherardi S.; Kwek K.; Russel A.; London W.; Buxton A.; Ashton L.; Sartorelli A.; Cohn S.; Schwab M.; Marshall G; Perini G.; Norris M.
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells
2011 A. Porro; N. Iraci; S. Soverini; D. Diolaiti; S. Gherardi; C. Terragna; S. Durante; E. Valli; T. Kalebic; R. Bernardoni; C. Perrod; M. Haber; M.D. Norris; M. Baccarani; G. Martinelli; G. Perini
Mutations in the 5' UTR of ANKRD26, the ankirin repeat domain 26 gene, cause an autosomal-dominant form of inherited thrombocytopenia, THC2
2011 Pippucci T;Savoia A;Perrotta S;Pujol-Moix N;Noris P;Castegnaro G;Pecci A;Gnan C;Punzo F;Marconi C;Gherardi S;Loffredo G;De Rocco D;Scianguetta S;Barozzi S;Magini P;Bozzi V;Dezzani L;Di Stazio M;Ferraro M;Perini G;Seri M;Balduini CL
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability.
2011 G.M. Marshall; P.Y. Liu; S. Gherardi; C.J. Scarlett; A. Bedalov; N. Xu; N. Iraci; E. Valli; D. Ling; W. Thomas; M. van Bekkum; E. Sekyere; K. Jankowski; T. Trahair; K.L. Mackenzie; M. Haber; M.D. Norris; A.V. Biankin; G. Perini; T. Liu.
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells
2010 Porro A.; Haber M.; Diolaiti D.; Iraci N.; Henderson M.; Gherardi S.; Valli E.; Munoz M.A.; Xue C.; Flemming C.; Schwab M.; Wong J.H.; Marshall G.M.; Della Valle G.; Norris M.D.; Perini G.
p53 is a direct transcriptional target of MYCN in neuroblastoma.
2010 Chen L.; Iraci N.; Gherardi S.; Gamble L.D.; Wood K.M.; Perini G.; Lunec J.; Tweddle D.A.
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects
2010 Marshall G.M.; Gherardi S.; Xu N.; Neiron Z.; Trahair T.; Scarlett C.J.; Chang D.K.; Liu P.Y.; Jankowski K.; Iraci N.; Haber M.; Norris M.D.; Keating J.; Sekyere E.; Jonquieres G.; Stossi F.; Katzenellenbogen B.S.; Biankin AV; Perini G.; Liu T.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Transcriptional and epigenetic analyses of the DMD locus reveal novel cisâacting DNA elements that govern muscle dystrophin expression | Gherardi, Samuele; Bovolenta, Matteo; Passarelli, Chiara; Falzarano, Maria Sofia; Pigini, Paolo; ...Scotton, Chiara; Neri, Marcella; Armaroli, Annarita; Osman, Hana; Selvatici, Rita; Gualandi, Francesca; Recchia, Alessandra; Mora, Marina; Bernasconi, Pia; Maggi, Lorenzo; Morandi, Lucia; Ferlini, Alessandra; Perini, Giovanni | 2017-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS | - | 1.01 Articolo in rivista | - |
| MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma | Lau, Diana T; Flemming, Claudia L; Gherardi, Samuele; Perini, Giovanni; Oberthuer, André; Fischer..., Matthias; Juraeva, Dilafruz; Brors, Benedikt; Xue, Chengyuan; Norris, Murray D; Marshall, Glenn M; Haber, Michelle; Fletcher, Jamie I; Ashton, Lesley J | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma | Evans, Laura; Chen, Lindi; Milazzo, Giorgio; Gherardi, Samuele; Perini, Giovanni; Willmore, Elain...e; Newell, David R.; Tweddle, Deborah A. | 2015-01-01 | CANCER LETTERS | - | 1.01 Articolo in rivista | - |
| WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma | Sun, Yuting; Bell, Jessica L; Carter, Daniel; Gherardi, Samuele; Poulos, Rebecca C; Milazzo, Gior...gio; Wong, Jason W H; Al-Awar, Rima; Tee, Andrew E; Liu, Pei Y; Liu, Bing; Atmadibrata, Bernard; Wong, Matthew; Trahair, Toby; Zhao, Quan; Shohet, Jason M; Haupt, Ygal; Schulte, Johannes H; Brown, Peter J; Arrowsmith, Cheryl H; Vedadi, Masoud; Mackenzie, Karen L; Hüttelmaier, Stefan; Perini, Giovanni; Marshall, Glenn M; Braithwaite, Antony; Liu, Tao | 2015-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | Cancer Res-2015-Sun-5143-54.pdf |
| MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. | Gherardi S; Valli E; Erriquez D; Perini G. | 2013-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. | Corvetta D; Chayka O; Gherardi S; D'Acunto CW; Cantilena S; Valli E; Piotrowska I; Perini G; Sala A. | 2013-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma | Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R.... Wagenaar; Michael R. Green | 2012-01-01 | - | - | 4.03 Poster | - |
| N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma | Fletcher J.I.; Gherardi S.; Murray J.; Burkhart C.A.; Russell A.; Valli E.; Smith J.; Oberthuer A....; Ashton L.J.; London W.B.; Marshall G.M.; Norris M.D.; Perini G.; Haber M. | 2012-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms. | Bovolenta M.; Erriquez D.; Valli E.; Brioschi S.; Scotton C.; Neri M.; Falzarano M.S.; Gherardi S....; Fabris M.; Rimessi P.; Gualandi F.; Perini G.; Ferlini A. | 2012-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF | Iraci N.; Diolaiti D.; Papa A.; Porro A.; Valli E.; Gherardi S.; Herold S.; Eilers M.; Bernardoni... R.; Della Valle G.; Perini G. | 2011-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux | Henderson M.; Porro A.; Munoz M.; Iraci N.; Xue C.; Murray J.; Flemming C.; Smith J.; Fletcher J....; Gherardi S.; Kwek K.; Russel A.; London W.; Buxton A.; Ashton L.; Sartorelli A.; Cohn S.; Schwab M.; Marshall G; Perini G.; Norris M. | 2011-01-01 | JOURNAL OF THE NATIONAL CANCER INSTITUTE | - | 1.01 Articolo in rivista | - |
| c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells | A. Porro; N. Iraci; S. Soverini; D. Diolaiti; S. Gherardi; C. Terragna; S. Durante; E. Valli; T. ...Kalebic; R. Bernardoni; C. Perrod; M. Haber; M.D. Norris; M. Baccarani; G. Martinelli; G. Perini | 2011-01-01 | MOLECULAR CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Mutations in the 5' UTR of ANKRD26, the ankirin repeat domain 26 gene, cause an autosomal-dominant form of inherited thrombocytopenia, THC2 | Pippucci T;Savoia A;Perrotta S;Pujol-Moix N;Noris P;Castegnaro G;Pecci A;Gnan C;Punzo F;Marconi C...;Gherardi S;Loffredo G;De Rocco D;Scianguetta S;Barozzi S;Magini P;Bozzi V;Dezzani L;Di Stazio M;Ferraro M;Perini G;Seri M;Balduini CL | 2011-01-01 | AMERICAN JOURNAL OF HUMAN GENETICS | - | 1.01 Articolo in rivista | - |
| SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. | G.M. Marshall; P.Y. Liu; S. Gherardi; C.J. Scarlett; A. Bedalov; N. Xu; N. Iraci; E. Valli; D. Li...ng; W. Thomas; M. van Bekkum; E. Sekyere; K. Jankowski; T. Trahair; K.L. Mackenzie; M. Haber; M.D. Norris; A.V. Biankin; G. Perini; T. Liu. | 2011-01-01 | PLOS GENETICS | - | 1.01 Articolo in rivista | - |
| Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells | Porro A.; Haber M.; Diolaiti D.; Iraci N.; Henderson M.; Gherardi S.; Valli E.; Munoz M.A.; Xue C....; Flemming C.; Schwab M.; Wong J.H.; Marshall G.M.; Della Valle G.; Norris M.D.; Perini G. | 2010-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| p53 is a direct transcriptional target of MYCN in neuroblastoma. | Chen L.; Iraci N.; Gherardi S.; Gamble L.D.; Wood K.M.; Perini G.; Lunec J.; Tweddle D.A. | 2010-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects | Marshall G.M.; Gherardi S.; Xu N.; Neiron Z.; Trahair T.; Scarlett C.J.; Chang D.K.; Liu P.Y.; Ja...nkowski K.; Iraci N.; Haber M.; Norris M.D.; Keating J.; Sekyere E.; Jonquieres G.; Stossi F.; Katzenellenbogen B.S.; Biankin AV; Perini G.; Liu T. | 2010-01-01 | ONCOGENE | - | 1.01 Articolo in rivista | - |