GENNACCARO, LAURA
GENNACCARO, LAURA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder
2021 Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali, Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death
2021 Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvani G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E.
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
2023 Loi, Manuela; Bastianini, Stefano; Candini, Giulia; Rizzardi, Nicola; Medici, Giorgio; Papa, Valentina; Gennaccaro, Laura; Mottolese, Nicola; Tassinari, Marianna; Uguagliati, Beatrice; Berteotti, Chiara; Martire, Viviana Lo; Zoccoli, Giovanna; Cenacchi, Giovanna; Trazzi, Stefania; Bergamini, Christian; Ciani, Elisabetta
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019)
2019 Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E.
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder
2022 Medici, Giorgio; Tassinari, Marianna; Galvani, Giuseppe; Bastianini, Stefano; Gennaccaro, Laura; Loi, Manuela; Mottolese, Nicola; Alvente, Sara; Berteotti, Chiara; Sagona, Giulia; Lupori, Leonardo; Candini, Giulia; Baggett, Helen Rappe; Zoccoli, Giovanna; Giustetto, Maurizio; Muotri, Alysson; Pizzorusso, Tommaso; Nakai, Hiroyuki; Trazzi, Stefania; Ciani, Elisabetta
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist
2019 Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E.
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist
2020 Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder
2018 Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Martire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder
2018 Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martire, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta*
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons
2020 Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E.
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder
2021 Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari, Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder
2022 Tassinari, Marianna; Mottolese, Nicola; Galvani, Giuseppe; Ferrara, Domenico; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Candini, Giulia; Rimondini, Roberto; Ciani, Elisabetta; Trazzi, Stefania
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder
2020 Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O.; Rimondini R.; Ciani E.
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder
2021 Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Giuseppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice
2018 Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, Elisabetta*
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder | Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali..., Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani | 2021-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | Gennaccaro et al 2021GABA.pdf; Supplementary data.docx |
| Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death | Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvan...i G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E. | 2021-01-01 | AGING AND DISEASE | - | 1.01 Articolo in rivista | Gennaccaro et al 2021Age.pdf |
| Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder | Loi, Manuela; Bastianini, Stefano; Candini, Giulia; Rizzardi, Nicola; Medici, Giorgio; Papa, Vale...ntina; Gennaccaro, Laura; Mottolese, Nicola; Tassinari, Marianna; Uguagliati, Beatrice; Berteotti, Chiara; Martire, Viviana Lo; Zoccoli, Giovanna; Cenacchi, Giovanna; Trazzi, Stefania; Bergamini, Christian; Ciani, Elisabetta | 2023-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | 2023, Cardiac Functional and Structural Abnormalities, Loi-Bastianini.pdf; ijms-24-05552-s001.zip |
| CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019) | Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E. | 2019-01-01 | BRAIN PATHOLOGY | - | 1.01 Articolo in rivista | - |
| Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder | Medici, Giorgio; Tassinari, Marianna; Galvani, Giuseppe; Bastianini, Stefano; Gennaccaro, Laura; ...Loi, Manuela; Mottolese, Nicola; Alvente, Sara; Berteotti, Chiara; Sagona, Giulia; Lupori, Leonardo; Candini, Giulia; Baggett, Helen Rappe; Zoccoli, Giovanna; Giustetto, Maurizio; Muotri, Alysson; Pizzorusso, Tommaso; Nakai, Hiroyuki; Trazzi, Stefania; Ciani, Elisabetta | 2022-01-01 | NEUROTHERAPEUTICS | - | 1.01 Articolo in rivista | s13311-022-01295-8.pdf; supplemantary materials.zip |
| Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist | Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rim...ondini R.; Aicardi G.; Ciani E. | 2019-01-01 | FRONTIERS IN CELLULAR NEUROSCIENCE | - | 1.01 Articolo in rivista | fncel-13-00169.pdf |
| Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist |
Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa ...Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani |
2020-01-01 | - | - | 4.03 Poster | - |
| Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder | Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Mar...tire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta | 2018-01-01 | NEURAL PLASTICITY | - | 1.01 Articolo in rivista | - |
| Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder | Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martir...e, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta* | 2018-01-01 | NEURAL PLASTICITY | - | 1.01 Articolo in rivista | 9726950(1).pdf; Supplementary Materials.zip |
| Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons | Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E. | 2020-01-01 | MOLECULAR NEUROBIOLOGY | - | 1.01 Articolo in rivista | - |
| Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder | Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari..., Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania | 2021-01-01 | JOURNAL OF NEUROINFLAMMATION | - | 1.01 Articolo in rivista | Galvani et al 2021.pdf |
| Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder | Tassinari, Marianna; Mottolese, Nicola; Galvani, Giuseppe; Ferrara, Domenico; Gennaccaro, Laura; ...Loi, Manuela; Medici, Giorgio; Candini, Giulia; Rimondini, Roberto; Ciani, Elisabetta; Trazzi, Stefania | 2022-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-23-08719.pdf; ijms-23-08719-s001.zip |
| Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder | Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O....; Rimondini R.; Ciani E. | 2020-01-01 | NEUROPHARMACOLOGY | - | 1.01 Articolo in rivista | - |
| Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder | Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Gius...eppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | Loi et al 2021.pdf; ijms-1212824-supplementary.pdf |
| Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice | Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, E...lisabetta* | 2018-01-01 | EUROPEAN JOURNAL OF NEUROSCIENCE | - | 1.01 Articolo in rivista | - |