RINALDI, FRANCESCO
RINALDI, FRANCESCO
ARAG - AREA FINANZA E CONTABILITA'
Collaboratori
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery
2024 Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A.
An integrative structural study of the human full-length RAD52 at 2.2 Å resolution
2024 Balboni, Beatrice; Marotta, Roberto; Rinaldi, Francesco; Milordini, Giulia; Varignani, Giulia; Girotto, Stefania; Cavalli, Andrea
Combining computational and experimental methods to characterize the RAD51-BRC repeats interaction
2024 Bresciani V., Rinaldi F., Bernetti M., Masetti M.
Elucidating the RAD51-BRC repeats interaction by integrating computational and experimental approaches
2024 Bresciani V., Rinaldi F., Bernetti M., Masetti M.
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives
2024 Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; Myers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea
Structure-based approaches in synthetic lethality strategies
2024 Rinaldi F., Girotto S.
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer
2023 Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer
2023 Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A.
Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics
2023 Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics
2023 Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach
2023 Rinaldi Francesco, Girotto Stefania, Cavalli Andrea
Integration of computational and experimental biophysics reveals novel insights on the BRCA2 - RAD51 interaction
2023 Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer
2023 Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A.
Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies
2023 Balboni B.; Rinaldi F.; Previtali V.; Ciamarone A.; Girotto S.; Cavalli A.
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach
2022 Samuel Harry Myers , Viola Previtali, Laura Poppi, Francesco Rinaldi, Fabrizio Schipani, Jose Antonio Ortega, Francesca De Franco, Marina Veronesi, Roberto Pellicciari, Marinella Roberti, Stefania Girotto, Giuseppina Di Stefano, Andrea Cavalli
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer
2022 Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Franco F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A.
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination
2022 Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi, Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea
Unveiling the molecular mechanism of BRCA2-RAD51 interaction to tackle cancer onset
2022 Rinaldi F., Schipani F., Scietti L., Girotto S, Cavalli A.
RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer
2021 Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Gennari, Arianna; Rinaldi, Francesco; Armirotti, Andrea; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Tirelli, Nicola; Girotto, Stefania; Cavalli, Andrea
Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia
2019 Hutmacher C.; Volta L.; Rinaldi F.; Murer P.; Myburgh R.; Manz M.G.; Neri D.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery | Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti... M., Cavalli A. | 2024-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| An integrative structural study of the human full-length RAD52 at 2.2 Å resolution | Balboni, Beatrice; Marotta, Roberto; Rinaldi, Francesco; Milordini, Giulia; Varignani, Giulia; Gi...rotto, Stefania; Cavalli, Andrea | 2024-01-01 | COMMUNICATIONS BIOLOGY | - | 1.01 Articolo in rivista | - |
| Combining computational and experimental methods to characterize the RAD51-BRC repeats interaction | Bresciani V., Rinaldi F., Bernetti M., Masetti M. | 2024-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Elucidating the RAD51-BRC repeats interaction by integrating computational and experimental approaches | Bresciani V., Rinaldi F., Bernetti M., Masetti M. | 2024-01-01 | - | - | 4.03 Poster | - |
| New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives | Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; My...ers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea | 2024-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Structure-based approaches in synthetic lethality strategies | Rinaldi F., Girotto S. | 2024-01-01 | CURRENT OPINION IN STRUCTURAL BIOLOGY | - | 1.03 Recensione in rivista | - |
| A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer | Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di... Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli | 2023-01-01 | - | FEBS PRESS | 4.03 Poster | - |
| An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer | Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipan...i F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A. | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | 1-s2.0-S0223523423010814-mmc1.docx |
| Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics | Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A. | 2023-01-01 | - | - | 4.03 Poster | - |
| Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics | Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A. | 2023-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach | Rinaldi Francesco, Girotto Stefania, Cavalli Andrea | 2023-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Integration of computational and experimental biophysics reveals novel insights on the BRCA2 - RAD51 interaction | Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A. | 2023-01-01 | - | - | 4.03 Poster | - |
| Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer | Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi... M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A. | 2023-01-01 | ANGEWANDTE CHEMIE. INTERNATIONAL EDITION | - | 1.01 Articolo in rivista | Angew Chem Int Ed - 2023 - Rinaldi - Isolation and Characterization of Monomeric Human RAD51 A Novel Tool for-1.pdf |
| Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies | Balboni B.; Rinaldi F.; Previtali V.; Ciamarone A.; Girotto S.; Cavalli A. | 2023-01-01 | CANCERS | - | 1.01 Articolo in rivista | IRIS CRIS.pdf |
| Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach | Samuel Harry Myers , Viola Previtali, Laura Poppi, Francesco Rinaldi, Fabrizio Schipani, Jose Ant...onio Ortega, Francesca De Franco, Marina Veronesi, Roberto Pellicciari, Marinella Roberti, Stefania Girotto, Giuseppina Di Stefano, Andrea Cavalli | 2022-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer | Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Fran...co F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A. | 2022-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination | Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi,... Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea | 2022-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-23-08338-v3 (1).pdf |
| Unveiling the molecular mechanism of BRCA2-RAD51 interaction to tackle cancer onset | Rinaldi F., Schipani F., Scietti L., Girotto S, Cavalli A. | 2022-01-01 | - | - | 4.03 Poster | - |
| RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer | Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Gennari, Arianna; Rinaldi, Francesco; Ar...mirotti, Andrea; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Tirelli, Nicola; Girotto, Stefania; Cavalli, Andrea | 2021-01-01 | bioRxiv | - | 1.01 Articolo in rivista | - |
| Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia | Hutmacher C.; Volta L.; Rinaldi F.; Murer P.; Myburgh R.; Manz M.G.; Neri D. | 2019-01-01 | LEUKEMIA RESEARCH | - | 1.01 Articolo in rivista | - |