MANARA, MARIA CRISTINA
MANARA, MARIA CRISTINA
CENTRO DI INTERESSE STRATEGICO DI ATENEO ALMA MATER INSTITUTE ON HEALTHY PLANET
Personale esterno ed autonomi
Circulating IGF2BP3 enables risk stratification and predicts treatment response in Ewing sarcoma
2026 Mancarella, Caterina; De Feo, Alessandra; Dirignani, Irene; Simonetti, Elisa; Maioli, Margherita; Manara, Maria Cristina; Ferrari, Cristina; Costantino, Federica; Cesari, Marilena; Bazzocchi, Alberto; Ibrahim, Toni; Bianchi, Giuseppe; Gambarotti, Marco; Scotlandi, Katia
Talazoparib engages innate immune activation via PARP trapping–dependent cGAS/STING activation in Ewing Sarcoma
2026 Carrabotta, Marianna; Manara, Maria Cristina; Landuzzi, Lorena; Simonetti, Elisa; Nesca, Andrea; Pellegrini, Evelin; Maioli, Margherita; Avnet, Sofia; Ruzzi, Francesca; Salamanna, Francesca; Gambarotti, Marco; Lollini, Pier-Luigi; Scotlandi, Katia
Genomic profiling of a collection of patient-derived xenografts and cell lines identified ixabepilone as an active drug against chemo-resistant osteosarcoma
2025 Manara, Mc; Bruzzese, F; Formentini, L; Landuzzi, L; Pazzaglia, L; Laginestra, Ma; Carrabotta, M; Roca, Ms; Iannelli, F; Grumetti, L; Addi, L; Parra, A; Cristalli, C; Pasello, M; Bavelloni, A; Carreras, F; Ruzzi, F; Bianchi, G; Gambarotti, M; Righi, A; Budillon, A; Lollini, Pl; Scotlandi, K
CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1-targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape
2024 Pasello M.; Laginestra M.A.; Manara M.C.; Landuzzi L.; Ruzzi F.; Maioli M.; Pellegrini E.; De Feo A.; Lollini P.-L.; Scotlandi K.
Innovative Breakthroughs for the Treatment of Advanced and Metastatic Synovial Sarcoma
2023 Landuzzi L.; Manara M.C.; Pazzaglia L.; Lollini P.L.; Scotlandi K.
ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis
2022 Pasello, Michela; Giudice, Anna Maria; Cristalli, Camilla; Manara, Maria Cristina; Mancarella, Caterina; Parra, Alessandro; Serra, Massimo; Magagnoli, Giovanna; Cidre-Aranaz, Florencia; Grünewald, Thomas G P; Bini, Carla; Lollini, Pier-Luigi; Longhi, Alessandra; Donati, Davide Maria; Scotlandi, Katia
Bone Turnover Marker (BTM) Changes after Denosumab in Giant Cell Tumors of Bone (GCTB): A Phase II Trial Correlative Study
2022 Palmerini E.; Pazzaglia L.; Cevolani L.; Pratelli L.; Pierini M.; Quattrini I.; Carretta E.; Manara M.C.; Pasello M.; Frega G.; Paioli A.; Longhi A.; Cesari M.; Hakim R.; Ibrahim T.; Campanacci L.; Staals E.L.; Donati D.M.; Benassi M.S.; Scotlandi K.; Ferrari S.
Correction to: ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis
2022 Pasello, Michela; Giudice, Anna Maria; Cristalli, Camilla; Manara, Maria Cristina; Mancarella, Caterina; Parra, Alessandro; Serra, Massimo; Magagnoli, Giovanna; Cidre-Aranaz, Florencia; Grünewald, Thomas G P; Bini, Carla; Lollini, Pier-Luigi; Longhi, Alessandra; Donati, Davide Maria; Scotlandi, Katia
Integrated molecular characterization of patient-derived models reveals therapeutic strategies for treating CIC-DUX4 sarcoma
2022 Carrabotta, Marianna; Laginestra, Maria Antonella; Durante, Giorgio; Mancarella, Caterina; Landuzzi, Lorena; Parra, Alessandro; Ruzzi, Francesca; Toracchio, Lisa; De Feo, Alessandra; Giusti, Veronica; Pasello, Michela; Righi, Alberto; Lollini, Pier-Luigi; Palmerini, Emanuela; Donati, Davide Maria; Manara, Maria Cristina; Scotlandi, Katia
Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
2022 Chiarini, Francesca; Paganelli, Francesca; Balestra, Tommaso; Capanni, Cristina; Fazio, Antonietta; Manara, Maria Cristina; Landuzzi, Lorena; Petrini, Stefania; Evangelisti, Camilla; Lollini, Pier-Luigi; Martelli, Alberto M.; Lattanzi, Giovanna; Scotlandi, Katia
Targeting CD99 compromises the oncogenic effects of the chimera EWS-FLI1 by inducing re-expression of zyxin and inhibition of Gli1 activity
2022 Balestra, Tommaso; Manara, Maria Cristina; Laginestra, Maria Antonella; Pasello, Michela; De Feo, Alessandra; Bassi, Cristian; Guerzoni, Clara; Landuzzi, Lorena; Lollini, Pier-Luigi; Donati, Davide Maria; Negrini, Massimo; Magnani, Mauro; Scotlandi, Katia
Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma
2021 Landuzzi, Lorena; Manara, Maria Cristina; Lollini, Pier-Luigi; Scotlandi, Katia
Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma
2020 Sciandra M.; De Feo A.; Parra A.; Landuzzi L.; Lollini P.-L.; Manara M.C.; Mattia G.; Pontecorvi G.; Baricordi C.; Guerzoni C.; Bazzocchi A.; Longhi A.; Scotlandi K.
Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis
2020 Caterina Mancarella , Giulia Caldoni, Irene Ribolsi, Alessandro Parra , Maria Cristina Manara , Arthur M Mercurio , Andrea Morrione , Katia Scotlandi
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations
2019 Nanni, Patrizia; Landuzzi, Lorena; Manara, Maria Cristina; Righi, Alberto; Nicoletti, Giordano; Cristalli, Camilla; Pasello, Michela; Parra, Alessandro; Carrabotta, Marianna; Ferracin, Manuela; Palladini, Arianna; Ianzano, Marianna L; Giusti, Veronica; Ruzzi, Francesca; Magnani, Mauro; Donati, Davide Maria; Picci, Piero; Lollini, Pier-Luigi; Scotlandi, Katia
ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity
2019 Zucchini, Cinzia; Manara, Maria Cristina; Cristalli, Camilla; Carrabotta, Marianna; Greco, Sara; Pinca, Rosa Simona; Ferrari, Cristina; Landuzzi, Lorena; Pasello, Michela; Lollini, Pier-Luigi; Gambarotti, Marco; Donati, Davide Maria; Scotlandi, Katia
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy
2018 Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia
The role of zyxin as a mediator between CD99 and EWS-FLI1
2018 Balestra T, Manara MC, Scotlandi K
The Sex Influence on Response to Tumor Necrosis Factor-α Inhibitors and Remission in Axial Spondyloarthritis.
2018 Lubrano, E; Perrotta, Fm; Manara, M; D'Angelo, S; Addimanda, O; Ramonda, R; Punzi, L; Olivieri, I; Salvarani, C; Marchesoni, A.
Zyxin in Ewing sarcoma: a novel role as mediator between CD99 and EWS-FLI1
2018 Balestra T, Manara MC, Scotlandi K
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Circulating IGF2BP3 enables risk stratification and predicts treatment response in Ewing sarcoma | Mancarella, Caterina; De Feo, Alessandra; Dirignani, Irene; Simonetti, Elisa; Maioli, Margherita;... Manara, Maria Cristina; Ferrari, Cristina; Costantino, Federica; Cesari, Marilena; Bazzocchi, Alberto; Ibrahim, Toni; Bianchi, Giuseppe; Gambarotti, Marco; Scotlandi, Katia | 2026-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | - |
| Talazoparib engages innate immune activation via PARP trapping–dependent cGAS/STING activation in Ewing Sarcoma | Carrabotta, Marianna; Manara, Maria Cristina; Landuzzi, Lorena; Simonetti, Elisa; Nesca, Andrea; ...Pellegrini, Evelin; Maioli, Margherita; Avnet, Sofia; Ruzzi, Francesca; Salamanna, Francesca; Gambarotti, Marco; Lollini, Pier-Luigi; Scotlandi, Katia | 2026-01-01 | CANCER LETTERS | - | 1.01 Articolo in rivista | 1-s2.0-S0304383526004684-main.zip; 1-s2.0-S0304383526004684-mmc1.zip |
| Genomic profiling of a collection of patient-derived xenografts and cell lines identified ixabepilone as an active drug against chemo-resistant osteosarcoma | Manara, Mc; Bruzzese, F; Formentini, L; Landuzzi, L; Pazzaglia, L; Laginestra, Ma; Carrabotta, M;... Roca, Ms; Iannelli, F; Grumetti, L; Addi, L; Parra, A; Cristalli, C; Pasello, M; Bavelloni, A; Carreras, F; Ruzzi, F; Bianchi, G; Gambarotti, M; Righi, A; Budillon, A; Lollini, Pl; Scotlandi, K | 2025-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | Ixabepilone JECC.pdf |
| CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1-targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape | Pasello M.; Laginestra M.A.; Manara M.C.; Landuzzi L.; Ruzzi F.; Maioli M.; Pellegrini E.; De Feo... A.; Lollini P.-L.; Scotlandi K. | 2024-01-01 | JOURNAL OF CELL COMMUNICATION AND SIGNALING | - | 1.01 Articolo in rivista | Journal of Cell Communication and Signaling - 2024 - Pasello - CD99 contributes to the EWS FLI1 transcriptome by.pdf |
| Innovative Breakthroughs for the Treatment of Advanced and Metastatic Synovial Sarcoma | Landuzzi L.; Manara M.C.; Pazzaglia L.; Lollini P.L.; Scotlandi K. | 2023-01-01 | CANCERS | - | 1.01 Articolo in rivista | Synovial review 2 cancers-15-03887-v3.pdf |
| ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis | Pasello, Michela; Giudice, Anna Maria; Cristalli, Camilla; Manara, Maria Cristina; Mancarella, Ca...terina; Parra, Alessandro; Serra, Massimo; Magagnoli, Giovanna; Cidre-Aranaz, Florencia; Grünewald, Thomas G P; Bini, Carla; Lollini, Pier-Luigi; Longhi, Alessandra; Donati, Davide Maria; Scotlandi, Katia | 2022-01-01 | CELLULAR ONCOLOGY | - | 1.01 Articolo in rivista | ABCA6 Cellular Oncology.pdf; 13402_2022_713_MOESM9_ESM.zip |
| Bone Turnover Marker (BTM) Changes after Denosumab in Giant Cell Tumors of Bone (GCTB): A Phase II Trial Correlative Study | Palmerini E.; Pazzaglia L.; Cevolani L.; Pratelli L.; Pierini M.; Quattrini I.; Carretta E.; Mana...ra M.C.; Pasello M.; Frega G.; Paioli A.; Longhi A.; Cesari M.; Hakim R.; Ibrahim T.; Campanacci L.; Staals E.L.; Donati D.M.; Benassi M.S.; Scotlandi K.; Ferrari S. | 2022-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-14-02863-v2 (1).pdf |
| Correction to: ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis | Pasello, Michela; Giudice, Anna Maria; Cristalli, Camilla; Manara, Maria Cristina; Mancarella, Ca...terina; Parra, Alessandro; Serra, Massimo; Magagnoli, Giovanna; Cidre-Aranaz, Florencia; Grünewald, Thomas G P; Bini, Carla; Lollini, Pier-Luigi; Longhi, Alessandra; Donati, Davide Maria; Scotlandi, Katia | 2022-01-01 | CELLULAR ONCOLOGY | - | 1.01 Articolo in rivista | s13402-022-00735-z.pdf |
| Integrated molecular characterization of patient-derived models reveals therapeutic strategies for treating CIC-DUX4 sarcoma | Carrabotta, Marianna; Laginestra, Maria Antonella; Durante, Giorgio; Mancarella, Caterina; Landuz...zi, Lorena; Parra, Alessandro; Ruzzi, Francesca; Toracchio, Lisa; De Feo, Alessandra; Giusti, Veronica; Pasello, Michela; Righi, Alberto; Lollini, Pier-Luigi; Palmerini, Emanuela; Donati, Davide Maria; Manara, Maria Cristina; Scotlandi, Katia | 2022-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | CIC-DUX4 Cancer Res 2022.pdf; can-21-1222_supplementary_data_supp1-9.pdf; can-21-1222_supplementary_methods_and_figures_supp1-13.pdf |
| Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma | Chiarini, Francesca; Paganelli, Francesca; Balestra, Tommaso; Capanni, Cristina; Fazio, Antoniett...a; Manara, Maria Cristina; Landuzzi, Lorena; Petrini, Stefania; Evangelisti, Camilla; Lollini, Pier-Luigi; Martelli, Alberto M.; Lattanzi, Giovanna; Scotlandi, Katia | 2022-01-01 | CELL DEATH & DISEASE | - | 1.01 Articolo in rivista | Lamin Cell Death Dis.pdf; 41419_2022_4729_MOESM1_ESM.pdf |
| Targeting CD99 compromises the oncogenic effects of the chimera EWS-FLI1 by inducing re-expression of zyxin and inhibition of Gli1 activity | Balestra, Tommaso; Manara, Maria Cristina; Laginestra, Maria Antonella; Pasello, Michela; De Feo,... Alessandra; Bassi, Cristian; Guerzoni, Clara; Landuzzi, Lorena; Lollini, Pier-Luigi; Donati, Davide Maria; Negrini, Massimo; Magnani, Mauro; Scotlandi, Katia | 2022-01-01 | MOLECULAR CANCER THERAPEUTICS | - | 1.01 Articolo in rivista | - |
| Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma | Landuzzi, Lorena; Manara, Maria Cristina; Lollini, Pier-Luigi; Scotlandi, Katia | 2021-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-10-00416-v2.pdf |
| Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma | Sciandra M.; De Feo A.; Parra A.; Landuzzi L.; Lollini P.-L.; Manara M.C.; Mattia G.; Pontecorvi ...G.; Baricordi C.; Guerzoni C.; Bazzocchi A.; Longhi A.; Scotlandi K. | 2020-01-01 | JOURNAL OF CELL COMMUNICATION AND SIGNALING | - | 1.01 Articolo in rivista | - |
| Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis | Caterina Mancarella , Giulia Caldoni, Irene Ribolsi, Alessandro Parra , Maria Cristina Manara , A...rthur M Mercurio , Andrea Morrione , Katia Scotlandi | 2020-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-10-00994.pdf; file supplementari.zip |
| Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations | Nanni, Patrizia; Landuzzi, Lorena; Manara, Maria Cristina; Righi, Alberto; Nicoletti, Giordano; C...ristalli, Camilla; Pasello, Michela; Parra, Alessandro; Carrabotta, Marianna; Ferracin, Manuela; Palladini, Arianna; Ianzano, Marianna L; Giusti, Veronica; Ruzzi, Francesca; Magnani, Mauro; Donati, Davide Maria; Picci, Piero; Lollini, Pier-Luigi; Scotlandi, Katia | 2019-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | PDX bone Sci Rep.pdf |
| ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity | Zucchini, Cinzia; Manara, Maria Cristina; Cristalli, Camilla; Carrabotta, Marianna; Greco, Sara; ...Pinca, Rosa Simona; Ferrari, Cristina; Landuzzi, Lorena; Pasello, Michela; Lollini, Pier-Luigi; Gambarotti, Marco; Donati, Davide Maria; Scotlandi, Katia | 2019-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | ROCK2 JECCR 2019.pdf |
| A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy | Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Loren...a; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia | 2018-01-01 | MOLECULAR CANCER THERAPEUTICS | - | 1.01 Articolo in rivista | - |
| The role of zyxin as a mediator between CD99 and EWS-FLI1 | Balestra T, Manara MC, Scotlandi K | 2018-01-01 | - | - | 4.03 Poster | - |
| The Sex Influence on Response to Tumor Necrosis Factor-α Inhibitors and Remission in Axial Spondyloarthritis. | Lubrano, E; Perrotta, Fm; Manara, M; D'Angelo, S; Addimanda, O; Ramonda, R; Punzi, L; Olivieri, I...; Salvarani, C; Marchesoni, A. | 2018-01-01 | THE JOURNAL OF RHEUMATOLOGY | - | 1.01 Articolo in rivista | - |
| Zyxin in Ewing sarcoma: a novel role as mediator between CD99 and EWS-FLI1 | Balestra T, Manara MC, Scotlandi K | 2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |