GASPARRE, GIUSEPPE
GASPARRE, GIUSEPPE
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Docenti di ruolo di Ia fascia
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism
2010 G. Romeo; G. Gasparre; A.M. Porcelli; M. Rugolo
A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme
2015 Michele Vidone;Rosanna Clima;Mariangela Santorsola;Claudia Calabrese;Giulia Girolimetti;Ivana Kurelac;Laura Benedetta Amato;Luisa Iommarini;Elisa Trevisan;Marco Leone;Riccardo Soffietti;Isabella Morra;Giuliano Faccani;Marcella Attimonelli;Anna Maria Porcelli;Giuseppe Gasparre
A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma
2016 Calabrese, Francesco Maria; Clima, Rosanna; Pignataro, Piero; Lasorsa, Vito Alessandro; Hogarty, Michael D.; Castellano, Aurora; Conte, Massimo; Tonini, Gian Paolo; Iolascon, Achille; Gasparre, Giuseppe; Capasso, Mario
A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma
2019 Kurelac, Ivana; Abarrategi, Ander; Ragazzi, Moira; Iommarini, Luisa; Umesh Ganesh, Nikkitha; Snoeks, Thomas; Bonnet, Dominique; Porcelli, Anna Maria; Malanchi, Ilaria; Gasparre, Giuseppe
A multi-parametric workflow for the prioritization of mitochondrial DNA variants of clinical interest
2016 Santorsola, Mariangela; Calabrese, Claudia; Girolimetti, Giulia; Diroma, Maria Angela; Gasparre, Giuseppe; Attimonelli, Marcella
A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype.
2014 Magini P;Pippucci T;Tsai IC;Coppola S;Stellacci E;Bartoletti-Stella A;Turchetti D;Graziano C;Cenacchi G;Neri I;Cordelli DM;Marchiani V;Bergamaschi R;Gasparre G;Neri G;Mazzanti L;Patrizi A;Franzoni E;Romeo G;Bordo D;Tartaglia M;Katsanis N;Seri M
A mutation screening of oncogenes, tumor suppressor gene TP53 and nuclear encoded mitochondrial complex I genes in oncocytic thyroid tumors
2015 Cecilia Evangelisti;Dario de Biase;Ivana Kurelac;Claudio Ceccarelli;Holger Prokisch;Thomas Meitinger;Paola Caria;Roberta Vanni;Giovanni Romeo;Giovanni Tallini;Giuseppe Gasparre;Elena Bonora
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function
2011 Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM
A Nonsense Mitochondrial DNA Mutation Associates with Dysfunction of HIF1α in a Von Hippel-Lindau Renal Oncocytoma
2019 De Luise, Monica; Guarnieri, Vito; Ceccarelli, Claudio; D’Agruma, Leonardo; Porcelli, Anna Maria; Gasparre, Giuseppe
A novel deleterious PTEN mutation in a patient with early-onset bilateral breast cancer.
2014 Pradella LM;Evangelisti C;Ligorio C;Ceccarelli C;Neri I;Zuntini R;Amato LB;Ferrari S;Martelli AM;Gasparre G;Turchetti D
A platform independent RNA-Seq protocol for the detection of transcriptome complexity
2013 Claudia Calabrese;Marina Mangiulli;Caterina Manzari;Anna Paluscio;Mariano Caratozzolo;Flaviana Marzano;Ivana Kurelac;Anna D’Erchia;Domenica D’Elia;Flavio Licciulli;Sabino Liuni;Ernesto Picardi;Marcella Attimonelli;Giuseppe Gasparre;Anna Porcelli;Graziano Pesole;Elisabetta Sbisà;Apollonia Tullo
A unique combination of rare mitochondrial ribosomal RNA variants affects the kinetics of complex I assembly
2016 Porcelli, Anna Maria; Calvaruso, Maria Antonietta; Iommarini, Luisa; Kurelac, Ivana; Zuntini, Roberta; Ferrari, Simona; Gasparre, Giuseppe
Abstract LB-236: Self-renewal of CD133hi cells by IL6/Notch3 signaling regulates endocrine resistance in metastatic breast cancers
2016 Sansone, Pasquale; Claudio, Ceccarelli; Berishaj, Marjan; Chang, Qing; Vinagolu, Rajasekhar; Perna, Fabiana; Bowman, Robert; Vidone, Michele; Daly, Laura; Nnoli, Jennifer; Santini, Donatella; Mario, Taffurelli; Shih, Natalie; Feldman, Michael; Mao, Jun James; Colameco, Christopher; Chen, Jinbo; Demichele, Angela; Fabbri, Nicola; Healey, John; Cricca, Monica; Gasparre, Giuseppe; Lyden, David; Bonafe, Massimiliano; Bromberg, Jacqueline F.
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder
2012 Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M.
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
2009 G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli.
Analysis of Mitochondrial Proteome of Cybrid Cells Harbouring a Truncative Mitochondrial DNA Mutation in Respiratory Complex I
2014 Clara Musicco;Antonella Cormio;Maria Antonietta Calvaruso;Luisa Iommarini;Giuseppe Gasparre;Anna Maria Porcelli;Anna Maria Timperio;Lello Zolla;Maria Nicola Gadaleta
BRCA-Associated Ovarian Cancer: From Molecular Genetics to Risk Management
2014 Giulia Girolimetti;Anna Myriam Perrone;Donatella Santini;Elena Barbieri;Flora Guerra;Simona Ferrari;Claudio Zamagni;Pierandrea De Iaco;Giuseppe Gasparre;Daniela Turchetti
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in renal oncocytoma
2008 E. De Laplanche; G. Gasparre; E. Hervouet; F. Mege-Lechevallier; C. Godinot; G. Romeo; H. Simonnet
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma
2008 Gasparre G.; Hervouet E.; de Laplanche E.; Demont J.; Pennisi L.F.; Colombel M.; Mège-Lechevallier F.; Scoazec J.Y.; Bonora E.; Smeets R.; Smeitink J.; Lazar V.; Lespinasse J.; Giraud S.; Godinot C.; Romeo G.; Simonnet H.
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis
2021 Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A cellular model for cancer progression: Role of mitochondrial mutations and metabolism | G. Romeo; G. Gasparre; A.M. Porcelli; M. Rugolo | 2010-01-01 | JOURNAL OF BIOTECHNOLOGY | - | 4.02 Riassunto (Abstract) | - |
| A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme | Michele Vidone;Rosanna Clima;Mariangela Santorsola;Claudia Calabrese;Giulia Girolimetti;Ivana Kur...elac;Laura Benedetta Amato;Luisa Iommarini;Elisa Trevisan;Marco Leone;Riccardo Soffietti;Isabella Morra;Giuliano Faccani;Marcella Attimonelli;Anna Maria Porcelli;Giuseppe Gasparre | 2015-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma | Calabrese, Francesco Maria; Clima, Rosanna; Pignataro, Piero; Lasorsa, Vito Alessandro; Hogarty, ...Michael D.; Castellano, Aurora; Conte, Massimo; Tonini, Gian Paolo; Iolascon, Achille; Gasparre, Giuseppe; Capasso, Mario | 2016-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma | Kurelac, Ivana; Abarrategi, Ander; Ragazzi, Moira; Iommarini, Luisa; Umesh Ganesh, Nikkitha; Snoe...ks, Thomas; Bonnet, Dominique; Porcelli, Anna Maria; Malanchi, Ilaria; Gasparre, Giuseppe | 2019-01-01 | JOURNAL OF CLINICAL MEDICINE | - | 1.01 Articolo in rivista | jcm-08-02184.pdf |
| A multi-parametric workflow for the prioritization of mitochondrial DNA variants of clinical interest | Santorsola, Mariangela; Calabrese, Claudia; Girolimetti, Giulia; Diroma, Maria Angela; Gasparre, ...Giuseppe; Attimonelli, Marcella | 2016-01-01 | HUMAN GENETICS | - | 1.01 Articolo in rivista | - |
| A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype. | Magini P;Pippucci T;Tsai IC;Coppola S;Stellacci E;Bartoletti-Stella A;Turchetti D;Graziano C;Cena...cchi G;Neri I;Cordelli DM;Marchiani V;Bergamaschi R;Gasparre G;Neri G;Mazzanti L;Patrizi A;Franzoni E;Romeo G;Bordo D;Tartaglia M;Katsanis N;Seri M | 2014-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| A mutation screening of oncogenes, tumor suppressor gene TP53 and nuclear encoded mitochondrial complex I genes in oncocytic thyroid tumors | Cecilia Evangelisti;Dario de Biase;Ivana Kurelac;Claudio Ceccarelli;Holger Prokisch;Thomas Meitin...ger;Paola Caria;Roberta Vanni;Giovanni Romeo;Giovanni Tallini;Giuseppe Gasparre;Elena Bonora | 2015-01-01 | BMC CANCER | - | 1.01 Articolo in rivista | 12885_2015_Article_1122.pdf |
| A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function | Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De ...Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM | 2011-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| A Nonsense Mitochondrial DNA Mutation Associates with Dysfunction of HIF1α in a Von Hippel-Lindau Renal Oncocytoma | De Luise, Monica; Guarnieri, Vito; Ceccarelli, Claudio; D’Agruma, Leonardo; Porcelli, Anna Maria;... Gasparre, Giuseppe | 2019-01-01 | OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | - | 1.01 Articolo in rivista | 8069583_c.pdf |
| A novel deleterious PTEN mutation in a patient with early-onset bilateral breast cancer. | Pradella LM;Evangelisti C;Ligorio C;Ceccarelli C;Neri I;Zuntini R;Amato LB;Ferrari S;Martelli AM;...Gasparre G;Turchetti D | 2014-01-01 | BMC CANCER | - | 1.01 Articolo in rivista | 1471-2407-14-70.pdf |
| A platform independent RNA-Seq protocol for the detection of transcriptome complexity | Claudia Calabrese;Marina Mangiulli;Caterina Manzari;Anna Paluscio;Mariano Caratozzolo;Flaviana Ma...rzano;Ivana Kurelac;Anna D’Erchia;Domenica D’Elia;Flavio Licciulli;Sabino Liuni;Ernesto Picardi;Marcella Attimonelli;Giuseppe Gasparre;Anna Porcelli;Graziano Pesole;Elisabetta Sbisà;Apollonia Tullo | 2013-01-01 | BMC GENOMICS | - | 1.01 Articolo in rivista | 1471-2164-14-855.pdf; 12864_2013_5558_MOESM1_ESM.doc; 12864_2013_5558_MOESM2_ESM.xls; 12864_2013_5558_MOESM3_ESM.doc |
| A unique combination of rare mitochondrial ribosomal RNA variants affects the kinetics of complex I assembly | Porcelli, Anna Maria; Calvaruso, Maria Antonietta; Iommarini, Luisa; Kurelac, Ivana; Zuntini, Rob...erta; Ferrari, Simona; Gasparre, Giuseppe | 2016-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| Abstract LB-236: Self-renewal of CD133hi cells by IL6/Notch3 signaling regulates endocrine resistance in metastatic breast cancers | Sansone, Pasquale; Claudio, Ceccarelli; Berishaj, Marjan; Chang, Qing; Vinagolu, Rajasekhar; Pern...a, Fabiana; Bowman, Robert; Vidone, Michele; Daly, Laura; Nnoli, Jennifer; Santini, Donatella; Mario, Taffurelli; Shih, Natalie; Feldman, Michael; Mao, Jun James; Colameco, Christopher; Chen, Jinbo; Demichele, Angela; Fabbri, Nicola; Healey, John; Cricca, Monica; Gasparre, Giuseppe; Lyden, David; Bonafe, Massimiliano; Bromberg, Jacqueline F. | 2016-01-01 | CANCER RESEARCH | - | 1.06 Abstract in rivista | - |
| Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder | Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; G...asparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. | G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi...; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli. | 2009-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| Analysis of Mitochondrial Proteome of Cybrid Cells Harbouring a Truncative Mitochondrial DNA Mutation in Respiratory Complex I | Clara Musicco;Antonella Cormio;Maria Antonietta Calvaruso;Luisa Iommarini;Giuseppe Gasparre;Anna ...Maria Porcelli;Anna Maria Timperio;Lello Zolla;Maria Nicola Gadaleta | 2014-01-01 | MOLECULAR BIOSYSTEMS | - | 1.01 Articolo in rivista | - |
| BRCA-Associated Ovarian Cancer: From Molecular Genetics to Risk Management | Giulia Girolimetti;Anna Myriam Perrone;Donatella Santini;Elena Barbieri;Flora Guerra;Simona Ferra...ri;Claudio Zamagni;Pierandrea De Iaco;Giuseppe Gasparre;Daniela Turchetti | 2014-01-01 | BIOMED RESEARCH INTERNATIONAL | - | 1.01 Articolo in rivista | - |
| Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in renal oncocytoma | E. De Laplanche; G. Gasparre; E. Hervouet; F. Mege-Lechevallier; C. Godinot; G. Romeo; H. Simonnet | 2008-01-01 | BULLETIN DU CANCER | - | 4.02 Riassunto (Abstract) | - |
| Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma | Gasparre G.; Hervouet E.; de Laplanche E.; Demont J.; Pennisi L.F.; Colombel M.; Mège-Lechevallie...r F.; Scoazec J.Y.; Bonora E.; Smeets R.; Smeitink J.; Lazar V.; Lespinasse J.; Giraud S.; Godinot C.; Romeo G.; Simonnet H. | 2008-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis | Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Ku...relac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana | 2021-01-01 | THE FEBS JOURNAL | - | 1.01 Articolo in rivista | - |