GASPARRE, GIUSEPPE
GASPARRE, GIUSEPPE
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Docenti di ruolo di Ia fascia
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism
2010-01-01 G. Romeo; G. Gasparre; A.M. Porcelli; M. Rugolo
A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype.
2014-01-01 Magini P;Pippucci T;Tsai IC;Coppola S;Stellacci E;Bartoletti-Stella A;Turchetti D;Graziano C;Cenacchi G;Neri I;Cordelli DM;Marchiani V;Bergamaschi R;Gasparre G;Neri G;Mazzanti L;Patrizi A;Franzoni E;Romeo G;Bordo D;Tartaglia M;Katsanis N;Seri M
Abstract LB-236: Self-renewal of CD133hi cells by IL6/Notch3 signaling regulates endocrine resistance in metastatic breast cancers
2016-01-01 Sansone, Pasquale; Claudio, Ceccarelli; Berishaj, Marjan; Chang, Qing; Vinagolu, Rajasekhar; Perna, Fabiana; Bowman, Robert; Vidone, Michele; Daly, Laura; Nnoli, Jennifer; Santini, Donatella; Mario, Taffurelli; Shih, Natalie; Feldman, Michael; Mao, Jun James; Colameco, Christopher; Chen, Jinbo; Demichele, Angela; Fabbri, Nicola; Healey, John; Cricca, Monica; Gasparre, Giuseppe; Lyden, David; Bonafe, Massimiliano; Bromberg, Jacqueline F.
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder
2012-01-01 Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M.
Analysis of Mitochondrial Proteome of Cybrid Cells Harbouring a Truncative Mitochondrial DNA Mutation in Respiratory Complex I
2014-01-01 Clara Musicco;Antonella Cormio;Maria Antonietta Calvaruso;Luisa Iommarini;Giuseppe Gasparre;Anna Maria Porcelli;Anna Maria Timperio;Lello Zolla;Maria Nicola Gadaleta
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I.
2008-01-01 Porcelli A.M.; Ghelli A.; Iommarini L.; Mariani E.; Hoque M.; Zanna C.; Gasparre G.; Rugolo M.
BRCA-Associated Ovarian Cancer: From Molecular Genetics to Risk Management
2014-01-01 Giulia Girolimetti;Anna Myriam Perrone;Donatella Santini;Elena Barbieri;Flora Guerra;Simona Ferrari;Claudio Zamagni;Pierandrea De Iaco;Giuseppe Gasparre;Daniela Turchetti
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in renal oncocytoma
2008-01-01 E. De Laplanche; G. Gasparre; E. Hervouet; F. Mege-Lechevallier; C. Godinot; G. Romeo; H. Simonnet
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma
2008-01-01 Gasparre G.; Hervouet E.; de Laplanche E.; Demont J.; Pennisi L.F.; Colombel M.; Mège-Lechevallier F.; Scoazec J.Y.; Bonora E.; Smeets R.; Smeitink J.; Lazar V.; Lespinasse J.; Giraud S.; Godinot C.; Romeo G.; Simonnet H.
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis
2021-01-01 Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana
Coenzyme Q10 depletion induces endogenous hypoxia in cultured cells
2018-01-01 Liparulo, Irene; Bergamini, Christian; Wenping, Wang; Masin, Luca; Rizzardi, Nicola; Kurelac, Ivana; Gasparre, Giuseppe; Bortolus, Marco; Romana, Fato
Complex I deficiency associated to mitochondrial DNA mutations in type I endometrial carcinoma
2012-01-01 Cormio A.; Guerra F.; Gasparre G.; Amati F.; Cormio G.; Selvaggi L.; Sardanelli A.M.; Gadaleta M.N.
Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes.
2013-01-01 Iommarini L.; Calvaruso M.A.; Kurelac I.; Gasparre G.; Porcelli A.M.
A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme
2015-01-01 Michele Vidone;Rosanna Clima;Mariangela Santorsola;Claudia Calabrese;Giulia Girolimetti;Ivana Kurelac;Laura Benedetta Amato;Luisa Iommarini;Elisa Trevisan;Marco Leone;Riccardo Soffietti;Isabella Morra;Giuliano Faccani;Marcella Attimonelli;Anna Maria Porcelli;Giuseppe Gasparre
A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma
2016-01-01 Calabrese, Francesco Maria; Clima, Rosanna; Pignataro, Piero; Lasorsa, Vito Alessandro; Hogarty, Michael D.; Castellano, Aurora; Conte, Massimo; Tonini, Gian Paolo; Iolascon, Achille; Gasparre, Giuseppe; Capasso, Mario
Contribution of ultrarare variants in mTOR pathway genes to sporadic focal epilepsies
2019-01-01 Pippucci, Tommaso; Licchetta, Laura; Baldassari, Sara; Marconi, Caterina; De Luise, Monica; Myers, Candace; Nardi, Elena; Provini, Federica; Cameli, Cinzia; Minardi, Raffaella; Bacchelli, Elena; Giordano, Lucio; Crichiutti, Giovanni; d'Orsi, Giuseppe; Seri, Marco; Gasparre, Giuseppe; Mefford, Heather C.; Tinuper, Paolo; Bisulli, Francesca; Santucci, Margherita
Current methodologies to detect circulating tumor cells: a focus on ovarian cancer
2021-01-01 Lemma, Silvia; Perrone, Anna M; De Iaco, Pierandrea; Gasparre, Giuseppe; Kurelac, Ivana
Deep sequencing unearths Nuclear mitochondrial Sequences under Leber's hereditary optic neuropathy-associated false heteroplasmic mitochondrial DNA variants.
2012-01-01 Petruzzella V.; Carrozzo R.; Calabrese C.; Dell'aglio R.; Trentadue R.; Piredda R.; Artuso L.; Rizza T.; Bianchi M.; Porcelli A.M.; Guerriero S.; Gasparre G.; Attimonelli M.
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III
2006-01-01 BONORA E.; PORCELLI A.M.; GASPARRE G.; BIONDI A.; GHELLI A.; CARELLI V.; BARACCA A.; TALLINI G.; MARTINUZZI A.; LENAZ G.; RUGOLO M.; ROMEO G.
Detecting Variants in the NBN Gene While Testing for Hereditary Breast Cancer: What to Do Next?
2021-01-01 Zuntini, Roberta; Bonora, Elena; Pradella, Laura Maria; Amato, Laura Benedetta; Vidone, Michele; De Fanti, Sara; Catucci, Irene; Cortesi, Laura; Medici, Veronica; Ferrari, Simona; Gasparre, Giuseppe; Peterlongo, Paolo; Sazzini, Marco; Turchetti, Daniela
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A cellular model for cancer progression: Role of mitochondrial mutations and metabolism | G. Romeo; G. Gasparre; A.M. Porcelli; M. Rugolo | 2010-01-01 | JOURNAL OF BIOTECHNOLOGY | - | 4.02 Riassunto (Abstract) | - |
| A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype. | Magini P;Pippucci T;Tsai IC;Coppola S;Stellacci E;Bartoletti-Stella A;Turchetti D;Graziano C;Cenacchi G;Neri I;Cordelli DM;Marchiani V;Bergamaschi R;Gasparre G;Neri G;Mazzanti L;Patrizi A;Franzoni E;Romeo G;Bordo D;Tartaglia M;Katsanis N;Seri M | 2014-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Abstract LB-236: Self-renewal of CD133hi cells by IL6/Notch3 signaling regulates endocrine resistance in metastatic breast cancers | Sansone, Pasquale; Claudio, Ceccarelli; Berishaj, Marjan; Chang, Qing; Vinagolu, Rajasekhar; Perna, Fabiana; Bowman, Robert; Vidone, Michele; Daly, Laura; Nnoli, Jennifer; Santini, Donatella; Mario, Taffurelli; Shih, Natalie; Feldman, Michael; Mao, Jun James; Colameco, Christopher; Chen, Jinbo; Demichele, Angela; Fabbri, Nicola; Healey, John; Cricca, Monica; Gasparre, Giuseppe; Lyden, David; Bonafe, Massimiliano; Bromberg, Jacqueline F. | 2016-01-01 | CANCER RESEARCH | - | 1.06 Abstract in rivista | - |
| Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder | Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| Analysis of Mitochondrial Proteome of Cybrid Cells Harbouring a Truncative Mitochondrial DNA Mutation in Respiratory Complex I | Clara Musicco;Antonella Cormio;Maria Antonietta Calvaruso;Luisa Iommarini;Giuseppe Gasparre;Anna Maria Porcelli;Anna Maria Timperio;Lello Zolla;Maria Nicola Gadaleta | 2014-01-01 | MOLECULAR BIOSYSTEMS | - | 1.01 Articolo in rivista | - |
| The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. | Porcelli A.M.; Ghelli A.; Iommarini L.; Mariani E.; Hoque M.; Zanna C.; Gasparre G.; Rugolo M. | 2008-01-01 | CELLULAR AND MOLECULAR LIFE SCIENCES | - | 1.01 Articolo in rivista | - |
| BRCA-Associated Ovarian Cancer: From Molecular Genetics to Risk Management | Giulia Girolimetti;Anna Myriam Perrone;Donatella Santini;Elena Barbieri;Flora Guerra;Simona Ferrari;Claudio Zamagni;Pierandrea De Iaco;Giuseppe Gasparre;Daniela Turchetti | 2014-01-01 | BIOMED RESEARCH INTERNATIONAL | - | 1.01 Articolo in rivista | - |
| Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in renal oncocytoma | E. De Laplanche; G. Gasparre; E. Hervouet; F. Mege-Lechevallier; C. Godinot; G. Romeo; H. Simonnet | 2008-01-01 | BULLETIN DU CANCER | - | 4.02 Riassunto (Abstract) | - |
| Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma | Gasparre G.; Hervouet E.; de Laplanche E.; Demont J.; Pennisi L.F.; Colombel M.; Mège-Lechevallier F.; Scoazec J.Y.; Bonora E.; Smeets R.; Smeitink J.; Lazar V.; Lespinasse J.; Giraud S.; Godinot C.; Romeo G.; Simonnet H. | 2008-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis | Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana | 2021-01-01 | THE FEBS JOURNAL | - | 1.01 Articolo in rivista | - |
| Coenzyme Q10 depletion induces endogenous hypoxia in cultured cells | Liparulo, Irene; Bergamini, Christian; Wenping, Wang; Masin, Luca; Rizzardi, Nicola; Kurelac, Ivana; Gasparre, Giuseppe; Bortolus, Marco; Romana, Fato | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| Complex I deficiency associated to mitochondrial DNA mutations in type I endometrial carcinoma | Cormio A.; Guerra F.; Gasparre G.; Amati F.; Cormio G.; Selvaggi L.; Sardanelli A.M.; Gadaleta M.N. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes. | Iommarini L.; Calvaruso M.A.; Kurelac I.; Gasparre G.; Porcelli A.M. | 2013-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme | Michele Vidone;Rosanna Clima;Mariangela Santorsola;Claudia Calabrese;Giulia Girolimetti;Ivana Kurelac;Laura Benedetta Amato;Luisa Iommarini;Elisa Trevisan;Marco Leone;Riccardo Soffietti;Isabella Morra;Giuliano Faccani;Marcella Attimonelli;Anna Maria Porcelli;Giuseppe Gasparre | 2015-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma | Calabrese, Francesco Maria; Clima, Rosanna; Pignataro, Piero; Lasorsa, Vito Alessandro; Hogarty, Michael D.; Castellano, Aurora; Conte, Massimo; Tonini, Gian Paolo; Iolascon, Achille; Gasparre, Giuseppe; Capasso, Mario | 2016-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Contribution of ultrarare variants in mTOR pathway genes to sporadic focal epilepsies | Pippucci, Tommaso; Licchetta, Laura; Baldassari, Sara; Marconi, Caterina; De Luise, Monica; Myers, Candace; Nardi, Elena; Provini, Federica; Cameli, Cinzia; Minardi, Raffaella; Bacchelli, Elena; Giordano, Lucio; Crichiutti, Giovanni; d'Orsi, Giuseppe; Seri, Marco; Gasparre, Giuseppe; Mefford, Heather C.; Tinuper, Paolo; Bisulli, Francesca; Santucci, Margherita | 2019-01-01 | ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | - | 1.01 Articolo in rivista | acn3.722.pdf; acn3722-sup-0001-supinfo.docx |
| Current methodologies to detect circulating tumor cells: a focus on ovarian cancer | Lemma, Silvia; Perrone, Anna M; De Iaco, Pierandrea; Gasparre, Giuseppe; Kurelac, Ivana | 2021-01-01 | AMERICAN JOURNAL OF CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Deep sequencing unearths Nuclear mitochondrial Sequences under Leber's hereditary optic neuropathy-associated false heteroplasmic mitochondrial DNA variants. | Petruzzella V.; Carrozzo R.; Calabrese C.; Dell'aglio R.; Trentadue R.; Piredda R.; Artuso L.; Rizza T.; Bianchi M.; Porcelli A.M.; Guerriero S.; Gasparre G.; Attimonelli M. | 2012-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III | BONORA E.; PORCELLI A.M.; GASPARRE G.; BIONDI A.; GHELLI A.; CARELLI V.; BARACCA A.; TALLINI G.; MARTINUZZI A.; LENAZ G.; RUGOLO M.; ROMEO G. | 2006-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Detecting Variants in the NBN Gene While Testing for Hereditary Breast Cancer: What to Do Next? | Zuntini, Roberta; Bonora, Elena; Pradella, Laura Maria; Amato, Laura Benedetta; Vidone, Michele; De Fanti, Sara; Catucci, Irene; Cortesi, Laura; Medici, Veronica; Ferrari, Simona; Gasparre, Giuseppe; Peterlongo, Paolo; Sazzini, Marco; Turchetti, Daniela | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | - |