Sfoglia per Autore
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update
2008 V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer.
2008 V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases
2008 A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone
2008 V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre
Synthesis of monomeric derivatives to probe Memoquin bivalent interactions
2008 ML. Bolognesi; A. Minarini; M. Bartolini; A. Cavalli; F. Mancini; V. Andrisano; M. Rosini; V. Tumiatti; C. Melchiorre
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics
2008 A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosini; C. Melchiorre
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush
2008 M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Tarozzi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre
Alzheimer's disease: new approaches to drug discovery.
2009 Bolognesi M.L.; Matera R.; Minarini A.; Rosini M.; Melchiorre C.
Circular Dichroism: a Study of Reversible Binding HSA Binding of Lipocrine.
2009 A. De Simone; M. Pistolozzi; M. Rosini; C. Melchiorre; C. Bertucci
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond
2009 Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C.
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease
2009 M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action
2009 Bolognesi ML; Bartolini M; Rosini M; Andrisano V; Melchiorre C.
Polymethylene tetraamine backbone as template for the development of biologically active polyamines
2009 A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks
2009 Bolognesi ML; Cavalli A; Bergamini C; Fato R; Lenaz G; Rosini M; Bartolini M; Andrisano V; Melchiorre C.
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy
2010 Melchiorre C; Bolognesi ML; Minarini A; Rosini M ; Tumiatti V
Curcumin analogs as multi-target antioxidants: focus on mitochondria.
2010 E. Simoni; M. Rosini; C. Bergamini; R. Fato; M.L. Bolognesi; A. Cavalli; R. Motterlini; G. Lenaz; C. Melchiorre
Mitochondria-directed antioxidants in Alzheimer's disease.
2010 M. Rosini; E. Simoni; M. L. Bolognesi; C. Bergamini; R. Fato; G. Lenaz; C. Melchiorre
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities
2010 Bolognesi ML; Bartolini M ; Mancini F ; Chiriano G ; Ceccarini L; Rosini M; Milelli A; Tumiatti V; Andrisano V; Melchiorre C
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities
2010 ML Bolognesi; M. Bartolini; F. Mancini; G. Chiriano; L. Ceccarini; M. Rosini; A. Milelli; V. Tumiatti; V. Andrisano; C. Melchiorre
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents.
2010 Simoni E.; Bergamini C.; Fato R.; Tarozzi A.; Bains S.; Motterlini R.; Cavalli A.; Bolognesi M.L.; Minarini A.; Hrelia P.; Lenaz G.; Rosini M.; Melchiorre C.
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update | V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre | 2008-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. | V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bart...olini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases | A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone | V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bart...olini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre | 2008-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
Synthesis of monomeric derivatives to probe Memoquin bivalent interactions | ML. Bolognesi; A. Minarini; M. Bartolini; A. Cavalli; F. Mancini; V. Andrisano; M. Rosini; V. Tum...iatti; C. Melchiorre | 2008-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics | A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosi...ni; C. Melchiorre | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush | M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Taroz...zi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Alzheimer's disease: new approaches to drug discovery. | Bolognesi M.L.; Matera R.; Minarini A.; Rosini M.; Melchiorre C. | 2009-01-01 | CURRENT OPINION IN CHEMICAL BIOLOGY | - | 1.01 Articolo in rivista | - |
Circular Dichroism: a Study of Reversible Binding HSA Binding of Lipocrine. | A. De Simone; M. Pistolozzi; M. Rosini; C. Melchiorre; C. Bertucci | 2009-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond | Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C. | 2009-01-01 | CURRENT PHARMACEUTICAL DESIGN | - | 1.01 Articolo in rivista | - |
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease | M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatt...i; V. Andrisano; I. R. Mellor; C. Melchiorre | 2009-01-01 | DRUGS OF THE FUTURE | - | 4.02 Riassunto (Abstract) | - |
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action | Bolognesi ML; Bartolini M; Rosini M; Andrisano V; Melchiorre C. | 2009-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
Polymethylene tetraamine backbone as template for the development of biologically active polyamines | A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre | 2009-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks | Bolognesi ML; Cavalli A; Bergamini C; Fato R; Lenaz G; Rosini M; Bartolini M; Andrisano V; Melchi...orre C. | 2009-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy | Melchiorre C; Bolognesi ML; Minarini A; Rosini M ; Tumiatti V | 2010-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Curcumin analogs as multi-target antioxidants: focus on mitochondria. | E. Simoni; M. Rosini; C. Bergamini; R. Fato; M.L. Bolognesi; A. Cavalli; R. Motterlini; G. Lenaz;... C. Melchiorre | 2010-01-01 | - | s. n. | 4.02 Riassunto (Abstract) | - |
Mitochondria-directed antioxidants in Alzheimer's disease. | M. Rosini; E. Simoni; M. L. Bolognesi; C. Bergamini; R. Fato; G. Lenaz; C. Melchiorre | 2010-01-01 | - | s. n. | 4.02 Riassunto (Abstract) | - |
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities | Bolognesi ML; Bartolini M ; Mancini F ; Chiriano G ; Ceccarini L; Rosini M; Milelli A; Tumiatti V...; Andrisano V; Melchiorre C | 2010-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities | ML Bolognesi; M. Bartolini; F. Mancini; G. Chiriano; L. Ceccarini; M. Rosini; A. Milelli; V. Tumi...atti; V. Andrisano; C. Melchiorre | 2010-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. | Simoni E.; Bergamini C.; Fato R.; Tarozzi A.; Bains S.; Motterlini R.; Cavalli A.; Bolognesi M.L....; Minarini A.; Hrelia P.; Lenaz G.; Rosini M.; Melchiorre C. | 2010-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
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