Chromatography is a powerful separation technique that has become an important unit operation when high levels of purity are required. The selectivity of the separation process depends on the interactions between the stationary phase and the mobile phase components. This gives the process great flexibility, as several functionalities can be incorporated into the stationary phase and stationary phases of different types and formats are possible. The focus of this volume is on ion-exchange chromatography, which is the most widely used process chromatography technique, and in this chapter, we will focus on ion-exchange membrane chromatography. Transport phenomena in membrane chromatography are discussed in detail highlighting the differences from packed column resin chromatography. We will then present different ways of stacking membranes into units and the limitations of existing module designs, finally we will present membrane adsorbers currently on the market and conclude with some application examples.
Onesti R., Giancaterino S., Roselli M., Bandini S., Boi C. (2023). Ion-exchange membrane chromatography. Amsterdam : Elsevier [10.1016/B978-0-443-15369-3.00026-2].
Ion-exchange membrane chromatography
Onesti R.Primo
Writing – Original Draft Preparation
;Giancaterino S.Writing – Review & Editing
;Roselli M.Writing – Review & Editing
;Bandini S.Writing – Review & Editing
;Boi C.
Ultimo
Writing – Original Draft Preparation
2023
Abstract
Chromatography is a powerful separation technique that has become an important unit operation when high levels of purity are required. The selectivity of the separation process depends on the interactions between the stationary phase and the mobile phase components. This gives the process great flexibility, as several functionalities can be incorporated into the stationary phase and stationary phases of different types and formats are possible. The focus of this volume is on ion-exchange chromatography, which is the most widely used process chromatography technique, and in this chapter, we will focus on ion-exchange membrane chromatography. Transport phenomena in membrane chromatography are discussed in detail highlighting the differences from packed column resin chromatography. We will then present different ways of stacking membranes into units and the limitations of existing module designs, finally we will present membrane adsorbers currently on the market and conclude with some application examples.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
