Development of a HPLC with colulometric detection methodology to measure olanzapine (OLA) and 4-N-desmethylolanzapine (DMO) levels in specific areas of rat brain after a single dose of OLA. Preliminary results are satisfactory in terms of sensitivity and selectivity.
Titolo: | Chromatographic analysis of atypical antipsychotic olanzapine and its main metabolite in rat plasma and brain samples after chronic administration. |
Autore/i: | SARACINO, MARIA ADDOLORATA; RIMONDINI GIORGINI, ROBERTO; GHEDINI, NADIA; RAGGI, MARIA AUGUSTA |
Autore/i Unibo: | |
Anno: | 2010 |
Titolo del libro: | XX National Meeting on Medicinal Chemistry |
Pagina iniziale: | 200 |
Pagina finale: | 200 |
Abstract: | Development of a HPLC with colulometric detection methodology to measure olanzapine (OLA) and 4-N-desmethylolanzapine (DMO) levels in specific areas of rat brain after a single dose of OLA. Preliminary results are satisfactory in terms of sensitivity and selectivity. |
Data prodotto definitivo in UGOV: | 17-dic-2010 |
Appare nelle tipologie: | 4.02 Riassunto (Abstract) |
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