Objectives: Fluoride increases the expansion and retards the setting time of F-doped calcium-silicate MTA cements. These cements may be successfully used as endodontic sealer. The assessment of the solubility of the endodontic cements allows to predict the loss of material from the surgical site, where they are in contact with physiological fluids (blood, tubular fluid). The aim of the study was to evaluate the solu- bility in deionized water (ISO 6876) or in simulated body fluid (DMEM) of designed F-doped calcium-silicate MTA cements with increasing amount of fluoride. Materials and methods: A calcium-silicate powder contain- ing di- and tricalcium-silicate, calcium sulphate and barium sulphate was prepared. An increasing percentage of fluo- ride (F0%, F1%, F5% and F10%) was added to the powder to obtain 4 cements. The cements were mixed with DPBS (liquid/powder ratio 0.22), placed into a mould (10 mm diam- eter; 2.21mm height) and stored at 37◦C and 98% relative humidity for the 75% of their own setting time. Each sam- ple (n=5 for each cement) was weighed (initial weight, IW) and immersed in 10mL of DMEM or deionized water keep- ing a vertical position. After 1 or 21 days the samples were dehydrated at 37 ◦ C and weighed (final weight, FW), then demoulded and the moulds weighed (mould weight, MW). The percentage of weight loss (solubility) was calculated as [(IW − FW)/(IW − MW)] × 100. Results: The solubility of all cements decrease over time (from 1 to 21 days) in both soaking solutions. High F concentra- tion increases the solubility of calcium-silicate MTA cements. The solubility in DMEM is lower than in water for all the cements; this difference is more evident at 21 days. Conclusions: The innovative MTA cement containing 1% of fluoride represents an interesting material for the endodon- tic surgery. The presence simulated body fluid solutions lows the solubility rate of endodontic MTA cements suggesting a reduced solubility in in vivo conditions.
A. Colin, C. Prati, G.A. Pelliccioni, M.G. Gandolfi (2010). Solubility in water or DMEM of F-doped MTA cements with increasing F-content. Oxford : Academic Press (Elsevier) [10.1016/j.dental.2010.08.152].
Solubility in water or DMEM of F-doped MTA cements with increasing F-content
PRATI, CARLO;PELLICCIONI, GIAN ANDREA;GANDOLFI, MARIA GIOVANNA
2010
Abstract
Objectives: Fluoride increases the expansion and retards the setting time of F-doped calcium-silicate MTA cements. These cements may be successfully used as endodontic sealer. The assessment of the solubility of the endodontic cements allows to predict the loss of material from the surgical site, where they are in contact with physiological fluids (blood, tubular fluid). The aim of the study was to evaluate the solu- bility in deionized water (ISO 6876) or in simulated body fluid (DMEM) of designed F-doped calcium-silicate MTA cements with increasing amount of fluoride. Materials and methods: A calcium-silicate powder contain- ing di- and tricalcium-silicate, calcium sulphate and barium sulphate was prepared. An increasing percentage of fluo- ride (F0%, F1%, F5% and F10%) was added to the powder to obtain 4 cements. The cements were mixed with DPBS (liquid/powder ratio 0.22), placed into a mould (10 mm diam- eter; 2.21mm height) and stored at 37◦C and 98% relative humidity for the 75% of their own setting time. Each sam- ple (n=5 for each cement) was weighed (initial weight, IW) and immersed in 10mL of DMEM or deionized water keep- ing a vertical position. After 1 or 21 days the samples were dehydrated at 37 ◦ C and weighed (final weight, FW), then demoulded and the moulds weighed (mould weight, MW). The percentage of weight loss (solubility) was calculated as [(IW − FW)/(IW − MW)] × 100. Results: The solubility of all cements decrease over time (from 1 to 21 days) in both soaking solutions. High F concentra- tion increases the solubility of calcium-silicate MTA cements. The solubility in DMEM is lower than in water for all the cements; this difference is more evident at 21 days. Conclusions: The innovative MTA cement containing 1% of fluoride represents an interesting material for the endodon- tic surgery. The presence simulated body fluid solutions lows the solubility rate of endodontic MTA cements suggesting a reduced solubility in in vivo conditions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
