The literature up to July 2008 dealing with catalytic enantioselective FC alkylation of aromatic compounds with nitroalkenes has been reviewed. Both metal-mediated and organocatalysis have been employed leading to a vast array of enantiomerically pure compounds most of them of interest in medicinal chemistry. An insight into the mechanism of the various catalytic methodologies is provided aimed at providing a rationale for the reactions treated.

Nitroalkenes

BERNARDI, LUCA;RICCI, ALFREDO MARCO
2009

Abstract

The literature up to July 2008 dealing with catalytic enantioselective FC alkylation of aromatic compounds with nitroalkenes has been reviewed. Both metal-mediated and organocatalysis have been employed leading to a vast array of enantiomerically pure compounds most of them of interest in medicinal chemistry. An insight into the mechanism of the various catalytic methodologies is provided aimed at providing a rationale for the reactions treated.
Catalytic Asymmetric Friedel-Crafts Alkylations
67
99
L. Bernardi; A. Ricci
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/83112
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