The literature up to July 2008 dealing with catalytic enantioselective FC alkylation of aromatic compounds with nitroalkenes has been reviewed. Both metal-mediated and organocatalysis have been employed leading to a vast array of enantiomerically pure compounds most of them of interest in medicinal chemistry. An insight into the mechanism of the various catalytic methodologies is provided aimed at providing a rationale for the reactions treated.
L. Bernardi, A. Ricci (2009). Nitroalkenes. WEIHEIM : Wiley-VCH.
Nitroalkenes
BERNARDI, LUCA;RICCI, ALFREDO MARCO
2009
Abstract
The literature up to July 2008 dealing with catalytic enantioselective FC alkylation of aromatic compounds with nitroalkenes has been reviewed. Both metal-mediated and organocatalysis have been employed leading to a vast array of enantiomerically pure compounds most of them of interest in medicinal chemistry. An insight into the mechanism of the various catalytic methodologies is provided aimed at providing a rationale for the reactions treated.File in questo prodotto:
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