Vasospastic angina is a form of ischemic heart disease caused by episodes of coronary artery increased focal vasomotor tone occurring typically at rest. Clinically episodes will manifest as angina at rest associated with ST-segment changes on the electrocardiogram (ECG) and promptly relieved by calcium channel antagonist (CCB) or short-acting nitrates. In recent years studies have demonstrated that coronary spasm can occur during physical or emotional stress and episodes could be associated with ST-segment depression on the ECG. Diffuse coronary artery spasm, characterizing vasotonic angina, is a manifestation of endothelial dysfunction involving the entire coronary tree and the coronary microcirculation is the major culprit. These patients will present with symptoms of stable and unstable angina and ST-segment depression on the ECG.

Vasospastic angina

Cenko E.;Bugiardini R.
2020

Abstract

Vasospastic angina is a form of ischemic heart disease caused by episodes of coronary artery increased focal vasomotor tone occurring typically at rest. Clinically episodes will manifest as angina at rest associated with ST-segment changes on the electrocardiogram (ECG) and promptly relieved by calcium channel antagonist (CCB) or short-acting nitrates. In recent years studies have demonstrated that coronary spasm can occur during physical or emotional stress and episodes could be associated with ST-segment depression on the ECG. Diffuse coronary artery spasm, characterizing vasotonic angina, is a manifestation of endothelial dysfunction involving the entire coronary tree and the coronary microcirculation is the major culprit. These patients will present with symptoms of stable and unstable angina and ST-segment depression on the ECG.
2020
Microcirculation: From Bench to Bedside
161
171
Cenko E.; Bugiardini R.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/767090
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