Vasospastic angina is a form of ischemic heart disease caused by episodes of coronary artery increased focal vasomotor tone occurring typically at rest. Clinically episodes will manifest as angina at rest associated with ST-segment changes on the electrocardiogram (ECG) and promptly relieved by calcium channel antagonist (CCB) or short-acting nitrates. In recent years studies have demonstrated that coronary spasm can occur during physical or emotional stress and episodes could be associated with ST-segment depression on the ECG. Diffuse coronary artery spasm, characterizing vasotonic angina, is a manifestation of endothelial dysfunction involving the entire coronary tree and the coronary microcirculation is the major culprit. These patients will present with symptoms of stable and unstable angina and ST-segment depression on the ECG.
Cenko E., Bugiardini R. (2020). Vasospastic angina. Cham : Springer International Publishing [10.1007/978-3-030-28199-1_10].
Vasospastic angina
Cenko E.;Bugiardini R.
2020
Abstract
Vasospastic angina is a form of ischemic heart disease caused by episodes of coronary artery increased focal vasomotor tone occurring typically at rest. Clinically episodes will manifest as angina at rest associated with ST-segment changes on the electrocardiogram (ECG) and promptly relieved by calcium channel antagonist (CCB) or short-acting nitrates. In recent years studies have demonstrated that coronary spasm can occur during physical or emotional stress and episodes could be associated with ST-segment depression on the ECG. Diffuse coronary artery spasm, characterizing vasotonic angina, is a manifestation of endothelial dysfunction involving the entire coronary tree and the coronary microcirculation is the major culprit. These patients will present with symptoms of stable and unstable angina and ST-segment depression on the ECG.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
