Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin alpha and rifaximin beta, and a poorly crystalline form named rifaximin gamma, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.

PROCESSES FOR THE PRODUCTION OF POLYMORPHIC FORMS OF RIFAXIMIN

BRAGA, DARIO;RIGHI, PAOLO;ROSINI, GOFFREDO
2008

Abstract

Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin alpha and rifaximin beta, and a poorly crystalline form named rifaximin gamma, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
2008
US 2008262232
VISCOMI G. C.; CAMPANA M.; BRAGA D.; CONFORTINI D.; CANNATA V.; RIGHI P.; ROSINI G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/73245
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