Serum smooth muscle antibodies (SMA) react with different components of the cytoskeletal network (actin, tubulin, vimentin, desmin, cytokeratins). Their presence characterizes both autoimmune (autoimmune hepatitis, coeliac disease) and viral diseases (chronic hepatitis C, infectious mononucleosis). When detected at titers higher than 1:80, they are considered a sensitive marker for type 1 autoimmune hepatitis (AIH-1), being found in up to 80% of cases.

Selmi C, Muratori P, Podda M, Bianchi FB. (2006). Smooth Muscle Antibodies. ST. LOUIS : Elsevier.

Smooth Muscle Antibodies

MURATORI, PAOLO;BIANCHI, FRANCESCO BIANCO
2006

Abstract

Serum smooth muscle antibodies (SMA) react with different components of the cytoskeletal network (actin, tubulin, vimentin, desmin, cytokeratins). Their presence characterizes both autoimmune (autoimmune hepatitis, coeliac disease) and viral diseases (chronic hepatitis C, infectious mononucleosis). When detected at titers higher than 1:80, they are considered a sensitive marker for type 1 autoimmune hepatitis (AIH-1), being found in up to 80% of cases.
2006
AUTOANTIBODIES
487
491
Selmi C, Muratori P, Podda M, Bianchi FB. (2006). Smooth Muscle Antibodies. ST. LOUIS : Elsevier.
Selmi C; Muratori P; Podda M; Bianchi FB.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/69099
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