It is disclosed a process for obtaining phenolic derivatives with high industrial interest in the pharmaceutical industry by using glycerol carbonate. Specifically, the process provides for a phenol substituted in position 2 to react with glycerol carbonate in the presence of a basic catalyst capable of activating the substituted phenol. The reaction can be carried out in the presence of a homogeneous catalyst or a heterogeneous catalyst, ensuring in any case good selectivity and high yields towards the desired product.
Process for obtaining phenolic derivatives by using glycerol carbonate
Tommaso Tabanelli;Fabrizio Cavani;
2018
Abstract
It is disclosed a process for obtaining phenolic derivatives with high industrial interest in the pharmaceutical industry by using glycerol carbonate. Specifically, the process provides for a phenol substituted in position 2 to react with glycerol carbonate in the presence of a basic catalyst capable of activating the substituted phenol. The reaction can be carried out in the presence of a homogeneous catalyst or a heterogeneous catalyst, ensuring in any case good selectivity and high yields towards the desired product.File in questo prodotto:
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